Novel orthobunyavirus identified in the cerebrospinal fluid of a Ugandan child with severe encephalopathy

Arthur W. D. Edridge, Martin Deijs, Ruth Namazzi, Cosimo Cristella, Maarten F. Jebbink, Irma Maurer, Neeltje A. Kootstra, Linda R. Buluma, Job B. M. van Woensel, Menno D. de Jong, Richard Idro, Michael Boele van Hensbroek, Lia van der Hoek

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A Ugandan child with an unexplained encephalitis was investigated using viral metagenomics. Several sequences from all segments of a novel orthobunyavirus were found. The S-segment, used for typing, showed 41% amino acid diversity to its closest relative. The virus was named Ntwetwe virus, after the hometown of the patient.
Original languageEnglish
Pages (from-to)139-142
JournalClinical Infectious Diseases
Issue number1
Publication statusPublished - 1 Jan 2019

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