Nieuwe therapeutische benadering van amyloïdose: Vooralsnog geen implicaties voor patiënten met de ziekte van Alzheimer

Translated title of the contribution: Novel therapeutic approach to amyloidosis: No implications as yet for patients with Alzheimer's disease

A. W. Lemstra*, P. Eikelenboom, E. W. Meijer, W. A. Van Gool

*Corresponding author for this work

Research output: Contribution to journalReview articleAcademicpeer-review


Many disorders, such as Alzheimer's disease and diabetes, are characterised by the misfolding and aggregation of proteins. Pepys et al. described a new approach of destabilising these aggregates by removing an associated protein, serum amyloid P. This offers opportunities for treating amyloidosis and possibly other protein folding diseases. Understanding the mechanism of this unique disease process and the different elements involved is necessary for future drug development.

Original languageDutch
Pages (from-to)1720-1723
Number of pages4
JournalNederlands Tijdschrift voor Geneeskunde
Issue number37
Publication statusPublished - 14 Sep 2002
Externally publishedYes

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