Nutritional interventions or exposures in infants and children aged up to 3 years and their effects on subsequent risk of overweight, obesity and body fat: a systematic review of systematic reviews

Bernadeta Patro-Golab, Bartomiej M. Zalewski, M. Kolodziej, S. Kouwenhoven, L. Poston, K.M. Godfrey, B. Koletzko, J. B. van Goudoever, H. Szajewska

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

This study, performed as part of the international EarlyNutrition research project (http://www.project-earlynutrition.eu), provides a systematic review of systematic reviews on the effects of nutritional interventions or exposures in children (up to 3 years of age) on the subsequent risk of obesity, overweight and adiposity. Electronic databases (including MEDLINE, Embase and Cochrane Library) were searched up until September 2015. Forty systematic reviews were included. A consistent association of breastfeeding with a modest reduction in the risk of later overweight and obesity in childhood and adulthood was found (the odds decreased by 13% based on high-quality studies), but residual confounding cannot be excluded. Lowering the protein content of infant formula is a promising intervention to reduce the risk of later overweight and obesity in children. There is no consistent evidence of an association of the age of introducing complementary foods, sugar-sweetened beverage or energy intake in early childhood with later overweight/obesity, but there are some indications of an association of protein intake during the complementary feeding period with later overweight/obesity. There was inadequate evidence to determine the effects of other nutritional interventions or exposures, including modifications of infant formula composition, fat intake or consumption of different food groups.
Original languageEnglish
Pages (from-to)1245-1257
Number of pages13
JournalObesity Reviews
Volume17
DOIs
Publication statusPublished - 2016

Cite this

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title = "Nutritional interventions or exposures in infants and children aged up to 3 years and their effects on subsequent risk of overweight, obesity and body fat: a systematic review of systematic reviews",
abstract = "This study, performed as part of the international EarlyNutrition research project (http://www.project-earlynutrition.eu), provides a systematic review of systematic reviews on the effects of nutritional interventions or exposures in children (up to 3 years of age) on the subsequent risk of obesity, overweight and adiposity. Electronic databases (including MEDLINE, Embase and Cochrane Library) were searched up until September 2015. Forty systematic reviews were included. A consistent association of breastfeeding with a modest reduction in the risk of later overweight and obesity in childhood and adulthood was found (the odds decreased by 13{\%} based on high-quality studies), but residual confounding cannot be excluded. Lowering the protein content of infant formula is a promising intervention to reduce the risk of later overweight and obesity in children. There is no consistent evidence of an association of the age of introducing complementary foods, sugar-sweetened beverage or energy intake in early childhood with later overweight/obesity, but there are some indications of an association of protein intake during the complementary feeding period with later overweight/obesity. There was inadequate evidence to determine the effects of other nutritional interventions or exposures, including modifications of infant formula composition, fat intake or consumption of different food groups.",
author = "Bernadeta Patro-Golab and Zalewski, {Bartomiej M.} and M. Kolodziej and S. Kouwenhoven and L. Poston and K.M. Godfrey and B. Koletzko and {van Goudoever}, {J. B.} and H. Szajewska",
note = "M1 - 12 ISI Document Delivery No.: ED8TW Times Cited: 0 Cited Reference Count: 61 Patro-Golab, B. Zalewski, B. M. Kolodziej, M. Kouwenhoven, S. Poston, L. Godfrey, K. M. Koletzko, B. van Goudoever, J. B. Szajewska, H. Godfrey, Keith/0000-0002-4643-0618 European Union [289346, 613977]; National Institute for Health Research through the NIHR Southampton Biomedical Research Centre; UK by Tommy's Charity; National Institute for Health Research through the NIHR Biomedical Research Centre at King's College London; Guys and St. Thomas' NHS Foundation Trust The research leading to these results has received funding from the European Union's Seventh Framework Programme (FP7/2007-2013), project EarlyNutrition under grant agreement no. 289346. K. M. G. was supported by the National Institute for Health Research through the NIHR Southampton Biomedical Research Centre and by the European Union's Seventh Framework Programme (FP7/2007-2013), projects EarlyNutrition and ODIN under grant agreement numbers 289346 and 613977. L. P. was supported in the UK by Tommy's Charity, the National Institute for Health Research through the NIHR Biomedical Research Centre at King's College London and Guys and St. Thomas' NHS Foundation Trust and by the European Union's Seventh Framework Programme (FP7/2007-2013), project EarlyNutrition under grant agreement no. 289346. 0 15 WILEY-BLACKWELL HOBOKEN OBES REV",
year = "2016",
doi = "10.1111/obr.12476",
language = "English",
volume = "17",
pages = "1245--1257",
journal = "Obesity Reviews",
issn = "1467-7881",
publisher = "Wiley-Blackwell",

}

Nutritional interventions or exposures in infants and children aged up to 3 years and their effects on subsequent risk of overweight, obesity and body fat: a systematic review of systematic reviews. / Patro-Golab, Bernadeta; Zalewski, Bartomiej M.; Kolodziej, M.; Kouwenhoven, S.; Poston, L.; Godfrey, K.M.; Koletzko, B.; van Goudoever, J. B.; Szajewska, H.

In: Obesity Reviews, Vol. 17, 2016, p. 1245-1257.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - Nutritional interventions or exposures in infants and children aged up to 3 years and their effects on subsequent risk of overweight, obesity and body fat: a systematic review of systematic reviews

AU - Patro-Golab, Bernadeta

AU - Zalewski, Bartomiej M.

AU - Kolodziej, M.

AU - Kouwenhoven, S.

AU - Poston, L.

AU - Godfrey, K.M.

AU - Koletzko, B.

AU - van Goudoever, J. B.

AU - Szajewska, H.

N1 - M1 - 12 ISI Document Delivery No.: ED8TW Times Cited: 0 Cited Reference Count: 61 Patro-Golab, B. Zalewski, B. M. Kolodziej, M. Kouwenhoven, S. Poston, L. Godfrey, K. M. Koletzko, B. van Goudoever, J. B. Szajewska, H. Godfrey, Keith/0000-0002-4643-0618 European Union [289346, 613977]; National Institute for Health Research through the NIHR Southampton Biomedical Research Centre; UK by Tommy's Charity; National Institute for Health Research through the NIHR Biomedical Research Centre at King's College London; Guys and St. Thomas' NHS Foundation Trust The research leading to these results has received funding from the European Union's Seventh Framework Programme (FP7/2007-2013), project EarlyNutrition under grant agreement no. 289346. K. M. G. was supported by the National Institute for Health Research through the NIHR Southampton Biomedical Research Centre and by the European Union's Seventh Framework Programme (FP7/2007-2013), projects EarlyNutrition and ODIN under grant agreement numbers 289346 and 613977. L. P. was supported in the UK by Tommy's Charity, the National Institute for Health Research through the NIHR Biomedical Research Centre at King's College London and Guys and St. Thomas' NHS Foundation Trust and by the European Union's Seventh Framework Programme (FP7/2007-2013), project EarlyNutrition under grant agreement no. 289346. 0 15 WILEY-BLACKWELL HOBOKEN OBES REV

PY - 2016

Y1 - 2016

N2 - This study, performed as part of the international EarlyNutrition research project (http://www.project-earlynutrition.eu), provides a systematic review of systematic reviews on the effects of nutritional interventions or exposures in children (up to 3 years of age) on the subsequent risk of obesity, overweight and adiposity. Electronic databases (including MEDLINE, Embase and Cochrane Library) were searched up until September 2015. Forty systematic reviews were included. A consistent association of breastfeeding with a modest reduction in the risk of later overweight and obesity in childhood and adulthood was found (the odds decreased by 13% based on high-quality studies), but residual confounding cannot be excluded. Lowering the protein content of infant formula is a promising intervention to reduce the risk of later overweight and obesity in children. There is no consistent evidence of an association of the age of introducing complementary foods, sugar-sweetened beverage or energy intake in early childhood with later overweight/obesity, but there are some indications of an association of protein intake during the complementary feeding period with later overweight/obesity. There was inadequate evidence to determine the effects of other nutritional interventions or exposures, including modifications of infant formula composition, fat intake or consumption of different food groups.

AB - This study, performed as part of the international EarlyNutrition research project (http://www.project-earlynutrition.eu), provides a systematic review of systematic reviews on the effects of nutritional interventions or exposures in children (up to 3 years of age) on the subsequent risk of obesity, overweight and adiposity. Electronic databases (including MEDLINE, Embase and Cochrane Library) were searched up until September 2015. Forty systematic reviews were included. A consistent association of breastfeeding with a modest reduction in the risk of later overweight and obesity in childhood and adulthood was found (the odds decreased by 13% based on high-quality studies), but residual confounding cannot be excluded. Lowering the protein content of infant formula is a promising intervention to reduce the risk of later overweight and obesity in children. There is no consistent evidence of an association of the age of introducing complementary foods, sugar-sweetened beverage or energy intake in early childhood with later overweight/obesity, but there are some indications of an association of protein intake during the complementary feeding period with later overweight/obesity. There was inadequate evidence to determine the effects of other nutritional interventions or exposures, including modifications of infant formula composition, fat intake or consumption of different food groups.

U2 - 10.1111/obr.12476

DO - 10.1111/obr.12476

M3 - Article

VL - 17

SP - 1245

EP - 1257

JO - Obesity Reviews

JF - Obesity Reviews

SN - 1467-7881

ER -