Aim: To evaluate the efficacy of carbon dioxide laser microsurgery for the treatment of carcinoma of the mobile tongue. Method: All patients with squamous cell carcinoma of the mobile tongue treated between 1986 and 1997 at the ENT Department of the University of Gottingen were retrospectively evaluated. Eighty-one previously untreated patients who had primary laser microsurgery for the treatment of the primary tumour were included in the analysis (27 patients stage 1,21 stage 2, 19 stage 3 and 14 stage 4). Results: The carcinomas were mainly localized on the side of the tongue (81.5%). Seventy percent of the patients underwent a (uni- or bilateral), mainly selective neck dissection. Nodal metastases were found in 28.4% of the patients. Twenty-eight percent had post-operative radiotherapy. Median follow-up interval was 49.3 months. The Kaplan-Meier 5-year local control rate was 78%. Eighteen (22.2%) patients died of TNM-related deaths, 16 (19.8%) of intercurrent disease and 9 (11.1%) due to a second primary tumour. The Kaplan-Meier 5-year overall survival rate was 64% for stage I and II and 40% for stage III and IV. The Kaplan-Meier 5-year recurrence-free survival rate was 68% and 55%, respectively. No invalidating articulation problems and major swallowing problems occurred postoperative. Conclusion: The results with carbon dioxide laser microsurgery in cancer of the mobile tongue are comparable with those of conventional surgery and radiotherapy with respect to local control and survival. Because of low morbidity and quick post-operative recovery carbon dioxide laser microsurgery is regarded the treatment of choice in these patients.
|Issue number||SUPPL. 1|
|Publication status||Published - 2001|