Off-label gebruik van medicatie voor de behandeling van deliri

Translated title of the contribution: Off-label use of medication for the treatment of delirium and behavioral disorders in the elderly

Rob Van Marum*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review


The prescription of off-label medication, as is portrayed in the cases of Koopmans and Borst, can have benevolent effects on the patients. However, it is important to realize that these cases relate to a specific selection of patients and that extrapolation to the larger population of nursing home residents requires great caution. In case of serious adverse drug events, the prescription of off-label medication, for which little evidence of efficacy exists, can have major legal consequences for the prescribing physician. The prescription of the newer off-label medication like memantine or the cholinesterase inhibitors can therefore only be justified when pharmaceutical interventions advised by generally accepted guidelines have failed due to lack of effect or unacceptable adverse reactions.

Original languageDutch
Pages (from-to)26-27
Number of pages2
JournalTijdschrift voor Verpleeghuisgeneeskunde
Issue number3
Publication statusPublished - 1 Nov 2004

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