Packaging RNA drugs into extracellular vesicles

Monique A J van Eijndhoven; S Rubina Baglio; D Michiel Pegtel

doi:10.1038/s41551-019-0514-0

Packaging RNA drugs into extracellular vesicles

Monique A J van Eijndhoven, S Rubina Baglio, D Michiel Pegtel

Research output: Contribution to journal › Comment/Letter to the editor › Academic

Abstract

The therapeutic dose of small interfering RNA can be reduced by endogenously expressing and packaging the RNA into extracellular vesicles through its integration with the backbone of a highly enriched pre-microRNA.

Original language	English
Pages (from-to)	6-8
Number of pages	3
Journal	Nature Biomedical Engineering
Volume	4
Issue number	6
DOIs	https://doi.org/10.1038/s41551-019-0514-0
Publication status	Published - Jan 2020

Access to Document

10.1038/s41551-019-0514-0

Link to publication in Scopus

Cite this

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title = "Packaging RNA drugs into extracellular vesicles",

abstract = "The therapeutic dose of small interfering RNA can be reduced by endogenously expressing and packaging the RNA into extracellular vesicles through its integration with the backbone of a highly enriched pre-microRNA.",

author = "{van Eijndhoven}, {Monique A J} and Baglio, {S Rubina} and Pegtel, {D Michiel}",

year = "2020",

month = jan,

doi = "10.1038/s41551-019-0514-0",

language = "English",

volume = "4",

pages = "6--8",

journal = "Nature Biomedical Engineering",

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AU - van Eijndhoven, Monique A J

AU - Baglio, S Rubina

AU - Pegtel, D Michiel

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N2 - The therapeutic dose of small interfering RNA can be reduced by endogenously expressing and packaging the RNA into extracellular vesicles through its integration with the backbone of a highly enriched pre-microRNA.

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DO - 10.1038/s41551-019-0514-0

M3 - Comment/Letter to the editor

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VL - 4

SP - 6

EP - 8

JO - Nature Biomedical Engineering

JF - Nature Biomedical Engineering

SN - 2157-846X

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