Pearly penile papules: still no reason for uneasiness

Cornelis J A Hogewoning, Maaike C G Bleeker, Adriaan J C van den Brule, Feja J Voorhorst, Rick E van Andel, Elle K Risse, Theo M Starink, Chris J L M Meijer

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

BACKGROUND: Penile lesions and pearly penile papules (PPP) are frequently found in male sexual partners of women with cervical intraepithelial neoplasia (CIN). The former have been associated with human papillomavirus (HPV).

OBJECTIVES: We estimated the prevalence of PPP in male sexual partners of women with CIN, and investigated the association between PPP and flat and papular penile lesions found in these men. We further evaluated a possible association between PPP and HPV, age, and CIN grade of the female partner.

METHODS: We evaluated by penoscopy the presence of HPV-associated penile lesions and PPP in 226 male sexual partners of women with CIN. HPV was tested by polymerase chain reaction-enzyme immunoassay and in situ hybridization.

RESULTS: The prevalence of PPP was 34% and was not associated with the presence of penile lesions or a positive HPV test. Age and CIN grade of the female partner were not related to the presence of PPP.

CONCLUSION: The prevalence of PPP in male sexual partners of women with CIN is comparable with the prevalence described in men of more diverse populations. Our data do not support a causative role for HPV in the genesis of PPP.

Original languageEnglish
Pages (from-to)50-4
Number of pages5
JournalJournal of the American Academy of Dermatology
Volume49
Issue number1
DOIs
Publication statusPublished - Jul 2003

Cite this

Hogewoning, C. J. A., Bleeker, M. C. G., van den Brule, A. J. C., Voorhorst, F. J., van Andel, R. E., Risse, E. K., ... Meijer, C. J. L. M. (2003). Pearly penile papules: still no reason for uneasiness. Journal of the American Academy of Dermatology, 49(1), 50-4. https://doi.org/10.1067/mjd.2003.420
Hogewoning, Cornelis J A ; Bleeker, Maaike C G ; van den Brule, Adriaan J C ; Voorhorst, Feja J ; van Andel, Rick E ; Risse, Elle K ; Starink, Theo M ; Meijer, Chris J L M. / Pearly penile papules : still no reason for uneasiness. In: Journal of the American Academy of Dermatology. 2003 ; Vol. 49, No. 1. pp. 50-4.
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abstract = "BACKGROUND: Penile lesions and pearly penile papules (PPP) are frequently found in male sexual partners of women with cervical intraepithelial neoplasia (CIN). The former have been associated with human papillomavirus (HPV).OBJECTIVES: We estimated the prevalence of PPP in male sexual partners of women with CIN, and investigated the association between PPP and flat and papular penile lesions found in these men. We further evaluated a possible association between PPP and HPV, age, and CIN grade of the female partner.METHODS: We evaluated by penoscopy the presence of HPV-associated penile lesions and PPP in 226 male sexual partners of women with CIN. HPV was tested by polymerase chain reaction-enzyme immunoassay and in situ hybridization.RESULTS: The prevalence of PPP was 34{\%} and was not associated with the presence of penile lesions or a positive HPV test. Age and CIN grade of the female partner were not related to the presence of PPP.CONCLUSION: The prevalence of PPP in male sexual partners of women with CIN is comparable with the prevalence described in men of more diverse populations. Our data do not support a causative role for HPV in the genesis of PPP.",
keywords = "Adult, Cervical Intraepithelial Neoplasia, Female, Humans, Male, Middle Aged, Papillomaviridae, Penile Diseases, Sexual Partners, Uterine Cervical Neoplasms, Journal Article, Research Support, Non-U.S. Gov't",
author = "Hogewoning, {Cornelis J A} and Bleeker, {Maaike C G} and {van den Brule}, {Adriaan J C} and Voorhorst, {Feja J} and {van Andel}, {Rick E} and Risse, {Elle K} and Starink, {Theo M} and Meijer, {Chris J L M}",
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Pearly penile papules : still no reason for uneasiness. / Hogewoning, Cornelis J A; Bleeker, Maaike C G; van den Brule, Adriaan J C; Voorhorst, Feja J; van Andel, Rick E; Risse, Elle K; Starink, Theo M; Meijer, Chris J L M.

In: Journal of the American Academy of Dermatology, Vol. 49, No. 1, 07.2003, p. 50-4.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - Pearly penile papules

T2 - still no reason for uneasiness

AU - Hogewoning, Cornelis J A

AU - Bleeker, Maaike C G

AU - van den Brule, Adriaan J C

AU - Voorhorst, Feja J

AU - van Andel, Rick E

AU - Risse, Elle K

AU - Starink, Theo M

AU - Meijer, Chris J L M

PY - 2003/7

Y1 - 2003/7

N2 - BACKGROUND: Penile lesions and pearly penile papules (PPP) are frequently found in male sexual partners of women with cervical intraepithelial neoplasia (CIN). The former have been associated with human papillomavirus (HPV).OBJECTIVES: We estimated the prevalence of PPP in male sexual partners of women with CIN, and investigated the association between PPP and flat and papular penile lesions found in these men. We further evaluated a possible association between PPP and HPV, age, and CIN grade of the female partner.METHODS: We evaluated by penoscopy the presence of HPV-associated penile lesions and PPP in 226 male sexual partners of women with CIN. HPV was tested by polymerase chain reaction-enzyme immunoassay and in situ hybridization.RESULTS: The prevalence of PPP was 34% and was not associated with the presence of penile lesions or a positive HPV test. Age and CIN grade of the female partner were not related to the presence of PPP.CONCLUSION: The prevalence of PPP in male sexual partners of women with CIN is comparable with the prevalence described in men of more diverse populations. Our data do not support a causative role for HPV in the genesis of PPP.

AB - BACKGROUND: Penile lesions and pearly penile papules (PPP) are frequently found in male sexual partners of women with cervical intraepithelial neoplasia (CIN). The former have been associated with human papillomavirus (HPV).OBJECTIVES: We estimated the prevalence of PPP in male sexual partners of women with CIN, and investigated the association between PPP and flat and papular penile lesions found in these men. We further evaluated a possible association between PPP and HPV, age, and CIN grade of the female partner.METHODS: We evaluated by penoscopy the presence of HPV-associated penile lesions and PPP in 226 male sexual partners of women with CIN. HPV was tested by polymerase chain reaction-enzyme immunoassay and in situ hybridization.RESULTS: The prevalence of PPP was 34% and was not associated with the presence of penile lesions or a positive HPV test. Age and CIN grade of the female partner were not related to the presence of PPP.CONCLUSION: The prevalence of PPP in male sexual partners of women with CIN is comparable with the prevalence described in men of more diverse populations. Our data do not support a causative role for HPV in the genesis of PPP.

KW - Adult

KW - Cervical Intraepithelial Neoplasia

KW - Female

KW - Humans

KW - Male

KW - Middle Aged

KW - Papillomaviridae

KW - Penile Diseases

KW - Sexual Partners

KW - Uterine Cervical Neoplasms

KW - Journal Article

KW - Research Support, Non-U.S. Gov't

U2 - 10.1067/mjd.2003.420

DO - 10.1067/mjd.2003.420

M3 - Article

VL - 49

SP - 50

EP - 54

JO - Journal of the American Academy of Dermatology

JF - Journal of the American Academy of Dermatology

SN - 0190-9622

IS - 1

ER -

Hogewoning CJA, Bleeker MCG, van den Brule AJC, Voorhorst FJ, van Andel RE, Risse EK et al. Pearly penile papules: still no reason for uneasiness. Journal of the American Academy of Dermatology. 2003 Jul;49(1):50-4. https://doi.org/10.1067/mjd.2003.420