EDTA plasma samples are optimal for accurate quantification of the ratio Abeta1-42/Abeta1-40. After collection, centrifugation conditions higher than 270xg, followed by a minimal delayed storage time is advised, omitting freeze-thaw cycles.
|Publication status||Published - 2019|
Teunissen, C. E., Verberk, I. M. W., Thijssen, E., Koelewijn, A., Flier, W. V. D., Stoops, E., & Vanderstichele, H. M. (2019). Pre-analytical sample handling effects on blood Amyloid beta1-42 and Amyloid beta1-40, measured by the novel SIMOA Amyblood assays.