Predictive value of sperm morphology and progressively motile sperm count for pregnancy outcomes in intrauterine insemination: Fertility and Sterility

L. Lemmens, Snjezana Kos, C. Beijer, J. W. Brinkman, F.A.L. van der Horst, L. van den Hoven, D. C. Kieslinger, N. J. van Trooyen-van Vrouwerff, A. Wolthuis, J. C. M. Hendriks, A. M. M. Wetzels, Quality Semen Section Dutch Fdn

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Abstract

Objective: To investigate the value of sperm parameters to predict an ongoing pregnancy outcome in couples treated with intrauterine insemination (IUI), during a methodologically stable period of time. Design: Retrospective, observational study with logistic regression analyses. Setting: University hospital. Patient(s): A total of 1,166 couples visiting the fertility laboratory for their first IUI episode, including 4,251 IUI cycles. Intervention(s): None. Main Outcome Measure(s): Sperm morphology, total progressively motile sperm count (TPMSC), and number of inseminated progressively motile spermatozoa (NIPMS); odds ratios (ORs) of the sperm parameters after the first IUI cycle and the first finished IUI episode; discriminatory accuracy of the multivariable model. Result(s): None of the sperm parameters was of predictive value for pregnancy after the first IUI cycle. In the first finished IUI episode, a positive relationship was found for
Original languageEnglish
Pages (from-to)1462-1468
Number of pages7
JournalFertility and Sterility
Volume105
DOIs
Publication statusPublished - 2016

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