Predictive value of sperm morphology and progressively motile sperm count for pregnancy outcomes in intrauterine insemination: Fertility and Sterility

L. Lemmens, Snjezana Kos, C. Beijer, J. W. Brinkman, F.A.L. van der Horst, L. van den Hoven, D. C. Kieslinger, N. J. van Trooyen-van Vrouwerff, A. Wolthuis, J. C. M. Hendriks, A. M. M. Wetzels, Quality Semen Section Dutch Fdn

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Abstract

Objective: To investigate the value of sperm parameters to predict an ongoing pregnancy outcome in couples treated with intrauterine insemination (IUI), during a methodologically stable period of time. Design: Retrospective, observational study with logistic regression analyses. Setting: University hospital. Patient(s): A total of 1,166 couples visiting the fertility laboratory for their first IUI episode, including 4,251 IUI cycles. Intervention(s): None. Main Outcome Measure(s): Sperm morphology, total progressively motile sperm count (TPMSC), and number of inseminated progressively motile spermatozoa (NIPMS); odds ratios (ORs) of the sperm parameters after the first IUI cycle and the first finished IUI episode; discriminatory accuracy of the multivariable model. Result(s): None of the sperm parameters was of predictive value for pregnancy after the first IUI cycle. In the first finished IUI episode, a positive relationship was found for
Original languageEnglish
Pages (from-to)1462-1468
Number of pages7
JournalFertility and Sterility
Volume105
DOIs
Publication statusPublished - 2016

Cite this

Lemmens, L., Kos, S., Beijer, C., Brinkman, J. W., van der Horst, F. A. L., van den Hoven, L., ... Semen Section Dutch Fdn, Q. (2016). Predictive value of sperm morphology and progressively motile sperm count for pregnancy outcomes in intrauterine insemination: Fertility and Sterility. Fertility and Sterility, 105, 1462-1468. https://doi.org/10.1016/j.fertnstert.2016.02.012