Prenatal diagnosis of congenital human cytomegalovirus infection in amniotic fluid by nucleic acid sequence-based amplification assay

M Grazia Revello, Daniele Lilleri, Maurizio Zavattoni, Milena Furione, Jaap Middeldorp, Giuseppe Gerna

Research output: Contribution to journalArticleAcademicpeer-review


Nucleic acid sequence-based amplification assays for detection of human cytomegalovirus (HCMV) immediate-early and pp67 mRNA in 65 amniotic fluid samples tested for prenatal diagnosis of congenital HCMV infection showed sensitivity, specificity, and negative and positive predictive values >90%.

Original languageEnglish
Pages (from-to)1772-4
Number of pages3
JournalJournal of Clinical Microbiology
Issue number4
Publication statusPublished - Apr 2003

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