Prevalencia de deterioro cognitivo en personas mayores de 80 años: Estudio COGMANLLEU

Translated title of the contribution: Prevalence of cognitive deterioration in people over 80 years old: COGMANLLEU study

E. Bufill*, A. Bartés, A. Moral, T. Casadevall, M. Codinachs, E. Zapater, J. C. Rovira, R. Pérez, P. Roura, R. Blesa

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Introduction. We want to detect the prevalence of cognitive prevalence deterioration in the elderly population of 80 years old or older, their grade of deterioration and the causal pathogenic entity. Method. Design: a cross-sectional population study, including a first phase of screening and a second one of diagnosis confirmation. Study subjects: a total of 877 elderly people of 80 years old or older belonging to the basic health care area of Man- lleu (Osona, Catalonia midlands). In the first phase, relatives and/or caregivers were interviewed, and the participating subjects underwent a set of tests. Those who obtained 24 points or less on the Mini-Mental State Examination (MMSE) and/or an equal Global Deterioration Scale (GDS) or over 3 were admitted to the second phase. During the second phase, a general and a neurological examination were performed, along with blood tests, cranial computed tomography scan and a neuropsychological study. DSM-IV criteria were used for dementia diagnosis, NINCDS-ADRA criteria for Alzheimer's disease (AD) and NINCS- AIREN for vascular dementia. Results. Half of the people over 80 years old had cognitive deterioration. One-fourth had dementia. A total of 70.3% of these dementias corresponded to AD (47.2% AD without vascular lesions and 23.1% AD with vascular lesions) and 12% corresponded to vascular dementia. The percentage of other degenerative dementias was 17.6%. Age and gender were observed to be associated to dementia. Conclusions. The prevalence of dementia in the COGMANLLEU study is similar to other European studies. AE is the most frequent dementia.

Original languageSpanish
Pages (from-to)102-107
Number of pages6
JournalNeurologia
Volume24
Issue number2
Publication statusPublished - 1 Mar 2009

Cite this

Bufill, E., Bartés, A., Moral, A., Casadevall, T., Codinachs, M., Zapater, E., ... Blesa, R. (2009). Prevalencia de deterioro cognitivo en personas mayores de 80 años: Estudio COGMANLLEU. Neurologia, 24(2), 102-107.