Abstract
A reliable overview of data on the prevalence of Chlamydia trachomatis (CT) in Russia is lacking and needed. All the available data on CT prevalence were analyzed in a systematic literature review on CT prevalence in Russia, strengthened with data from the multicenter study among 1263 people in the second-largest Russian megalopolis, St. Petersburg, testing for CT DNA in urethral, anal, cervical and prostate samples. A total of 10 articles met the inclusion criteria. The overall average prevalence of genital CT infections in Russian populations ranged from 2.9% to 33%. Risk factors included being symptomatic (P = 0.004; in men P < 0.001), being younger than 30 years (P = 0.001) and being a man who has sex with men (MSM) (P = 0.0084). Main limitations included the lack of studies in MSM. CT prevalence was higher in the groups where urethral and prostate secretion samples were pooled (5.2%-7.3% vs 3.2% in the urethra only). The data on CT prevalence in a range of Russian populations are analyzed and reported. Prostate secretions represent an additional sampling material for the study of CT infection in men. CT detection in some settings in St. Petersburg yielded levels of reliability comparable with internationally available tests. The initiation of screening programs for Chlamydia infections in Russia should be considered.
| Original language | English |
|---|---|
| Article number | ftx081 |
| Journal | Pathogens and Disease |
| Volume | 75 |
| Issue number | 7 |
| DOIs | |
| Publication status | Published - 1 Oct 2017 |
Cite this
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Prevalence of genital Chlamydia trachomatis infections in Russia : Systematic literature review and multicenter study. / Smelov, Vitaly; Thomas, Pierre; Ouburg, Sander; Morré, Servaas A.
In: Pathogens and Disease, Vol. 75, No. 7, ftx081, 01.10.2017.Research output: Contribution to journal › Short survey › Academic › peer-review
TY - JOUR
T1 - Prevalence of genital Chlamydia trachomatis infections in Russia
T2 - Systematic literature review and multicenter study
AU - Smelov, Vitaly
AU - Thomas, Pierre
AU - Ouburg, Sander
AU - Morré, Servaas A.
PY - 2017/10/1
Y1 - 2017/10/1
N2 - A reliable overview of data on the prevalence of Chlamydia trachomatis (CT) in Russia is lacking and needed. All the available data on CT prevalence were analyzed in a systematic literature review on CT prevalence in Russia, strengthened with data from the multicenter study among 1263 people in the second-largest Russian megalopolis, St. Petersburg, testing for CT DNA in urethral, anal, cervical and prostate samples. A total of 10 articles met the inclusion criteria. The overall average prevalence of genital CT infections in Russian populations ranged from 2.9% to 33%. Risk factors included being symptomatic (P = 0.004; in men P < 0.001), being younger than 30 years (P = 0.001) and being a man who has sex with men (MSM) (P = 0.0084). Main limitations included the lack of studies in MSM. CT prevalence was higher in the groups where urethral and prostate secretion samples were pooled (5.2%-7.3% vs 3.2% in the urethra only). The data on CT prevalence in a range of Russian populations are analyzed and reported. Prostate secretions represent an additional sampling material for the study of CT infection in men. CT detection in some settings in St. Petersburg yielded levels of reliability comparable with internationally available tests. The initiation of screening programs for Chlamydia infections in Russia should be considered.
AB - A reliable overview of data on the prevalence of Chlamydia trachomatis (CT) in Russia is lacking and needed. All the available data on CT prevalence were analyzed in a systematic literature review on CT prevalence in Russia, strengthened with data from the multicenter study among 1263 people in the second-largest Russian megalopolis, St. Petersburg, testing for CT DNA in urethral, anal, cervical and prostate samples. A total of 10 articles met the inclusion criteria. The overall average prevalence of genital CT infections in Russian populations ranged from 2.9% to 33%. Risk factors included being symptomatic (P = 0.004; in men P < 0.001), being younger than 30 years (P = 0.001) and being a man who has sex with men (MSM) (P = 0.0084). Main limitations included the lack of studies in MSM. CT prevalence was higher in the groups where urethral and prostate secretion samples were pooled (5.2%-7.3% vs 3.2% in the urethra only). The data on CT prevalence in a range of Russian populations are analyzed and reported. Prostate secretions represent an additional sampling material for the study of CT infection in men. CT detection in some settings in St. Petersburg yielded levels of reliability comparable with internationally available tests. The initiation of screening programs for Chlamydia infections in Russia should be considered.
KW - Chlamydia infections in MSM in Russia
KW - Chlamydia prevalence in Russia
KW - Chlamydia trachomatis in prostate secretion
KW - Genital Chlamydia trachomatis
KW - Russian NAATs
UR - http://www.scopus.com/inward/record.url?scp=85037031528&partnerID=8YFLogxK
U2 - 10.1093/femspd/ftx081
DO - 10.1093/femspd/ftx081
M3 - Short survey
VL - 75
JO - Pathogens and Disease
JF - Pathogens and Disease
SN - 2049-632X
IS - 7
M1 - ftx081
ER -