Prevalence of insomnia (symptoms) in T2D and association with metabolic parameters and glycemic control: meta-analysis

Anitra D M Koopman, Joline W Beulens, Tine Dijkstra, Frans Pouwer, Marijke A Bremmer, Annemieke van Straten, Femke Rutters

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OBJECTIVE: We aimed to determine the prevalence of insomnia and insomnia symptoms and its association with metabolic parameters and glycemic control in people with T2D in a systematic review and meta-analysis. DATASOURCES: A systematic literature search was conducted in Pubmed/Embase until March, 2018. STUDYSELECTION: Included studies described prevalence of insomnia or insomnia symptoms and/or its association with metabolic parameters or glycemic control in adults with T2D. DATAEXTRACTION: Data extraction was performed independently by two reviewers, on a standardized, pre-piloted form. An adaptation of Quality Assessment Tool for Quantitative Studies was used to assess the methodological quality of the included studies. DATASYNTHESIS: When possible, results were meta-analyzed using random-effects analysis and rated using GRADE. RESULTS: A total of 11.329 titles/abstracts were screened and 224 were read full text in duplicate, of which 78 studies were included. The pooled prevalence of insomnia (symptoms) in people with T2D was 39% (95%CI:34-44) with I 2 statistic of 100% (P
Original languageEnglish
Article numberdgz065
JournalJournal of Clinical Endocrinology and Metabolism
Issue number3
Early online date11 Oct 2019
Publication statusPublished - 1 Mar 2020

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