Probiotics for childhood functional gastrointestinal disorders: A systematic review and meta-analysis

Judith J. Korterink; Lize Ockeloen; Marc A. Benninga; Merit M. Tabbers; Mirrian Hilbink; Judith M. Deckers-Kocken

doi:10.1111/apa.12513

Probiotics for childhood functional gastrointestinal disorders: A systematic review and meta-analysis

Judith J. Korterink, Lize Ockeloen, Marc A. Benninga, Merit M. Tabbers, Mirrian Hilbink, Judith M. Deckers-Kocken

Research output: Contribution to journal › Review article › Academic › peer-review

Abstract

A systematic review and meta-analysis were performed to investigate the quantity and quality of the current evidence regarding the effect of different probiotic strains in the treatment of functional gastrointestinal disorders (FGID) in children and adolescents. Conclusion Probiotics are more effective than placebo in the treatment of patients with abdominal pain-related FGID, especially with respect to patients with irritable bowel syndrome. To date, however, probiotics have not proved effective for children with functional constipation. ©2013 Foundation Acta Pædiatrica. Published by John Wiley & Sons Ltd.

Original language	English
Pages (from-to)	365-372
Journal	Acta Paediatrica, International Journal of Paediatrics
Volume	103
Issue number	4
DOIs	https://doi.org/10.1111/apa.12513
Publication status	Published - 2014
Externally published	Yes

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10.1111/apa.12513

Cite this

Korterink, J. J., Ockeloen, L., Benninga, M. A., Tabbers, M. M., Hilbink, M., & Deckers-Kocken, J. M. (2014). Probiotics for childhood functional gastrointestinal disorders: A systematic review and meta-analysis. Acta Paediatrica, International Journal of Paediatrics, 103(4), 365-372. https://doi.org/10.1111/apa.12513

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abstract = "A systematic review and meta-analysis were performed to investigate the quantity and quality of the current evidence regarding the effect of different probiotic strains in the treatment of functional gastrointestinal disorders (FGID) in children and adolescents. Conclusion Probiotics are more effective than placebo in the treatment of patients with abdominal pain-related FGID, especially with respect to patients with irritable bowel syndrome. To date, however, probiotics have not proved effective for children with functional constipation. {\circledC}2013 Foundation Acta P{\ae}diatrica. Published by John Wiley & Sons Ltd.",

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Probiotics for childhood functional gastrointestinal disorders: A systematic review and meta-analysis. / Korterink, Judith J.; Ockeloen, Lize; Benninga, Marc A.; Tabbers, Merit M.; Hilbink, Mirrian; Deckers-Kocken, Judith M.

In: Acta Paediatrica, International Journal of Paediatrics, Vol. 103, No. 4, 2014, p. 365-372.

Research output: Contribution to journal › Review article › Academic › peer-review

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