Psychosocial development in survivors of childhood differentiated thyroid carcinoma: A cross-sectional study

Marloes Nies, Bernadette L. Dekker, Esther Sulkers, Gea A. Huizinga, Mariëlle S. Klein Hesselink, Heleen Maurice-Stam, Martha A. Grootenhuis, Adrienne H. Brouwers, Johannes G. M. Burgerhof, Eveline W. C. M. van Dam, Bas Havekes, Marry M. van den Heuvel-Eibrink, Eleonora P. M. Corssmit, Leontien C. M. Kremer, Romana T. Netea-Maier, Heleen J. H. van der Pal, Robin P. Peeters, John T. M. Plukker, C. cile M. Ronckers, Hanneke M. van Santen & 4 others Anouk N. A. van der Horst-Schrivers, Wim J. E. Tissing, Gianni Bocca, Thera P. Links

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Objective: The impact of childhood differentiated thyroid carcinoma (DTC) on psychosocial development has not yet been studied. The aim of this study was to evaluate the achievement of psychosocial developmental milestones in long-term survivors of childhood DTC. Design and methods: Survivors of childhood DTC diagnosed between 1970 and 2013 were included. Reasons for exclusion were age <18 or >35 years at follow-up, a follow-up period <5 years or diagnosis with DTC as a second malignant neoplasm. Survivors gathered peer controls of similar age and sex (n=30). A comparison group non-affected with cancer (n=508) and other childhood cancer survivors (CCS) were also used to compare psychosocial development. To assess the achievement of psychosocial milestones (social, autonomy and psychosexual development), the course of life questionnaire (CoLQ) was used. Results: We included 39 survivors of childhood DTC (response rate 83.0%, mean age at diagnosis 15.6 years, and mean age at evaluation 26.1 years). CoLQ scores did not significantly differ between survivors of childhood DTC and the two non-affected groups. CoLQ scores of childhood DTC survivors were compared to scores of other CCS diagnosed at similar ages (n= 76). DTC survivors scored significantly higher on social development than other CCS, but scores were similar on autonomy and psychosexual developmental scales. Conclusions: Survivors of childhood DTC showed similar development on social, autonomy, and psychosexual domains compared to non-affected individuals. Social development was slightly more favorable in DTC survivors than in other CCS, but was similar on autonomy and psychosexual domains.
Original languageEnglish
Pages (from-to)215-223
JournalEuropean Journal of Endocrinology
Volume178
Issue number3
DOIs
Publication statusPublished - 2018

Cite this

Nies, M., Dekker, B. L., Sulkers, E., Huizinga, G. A., Klein Hesselink, M. S., Maurice-Stam, H., ... Links, T. P. (2018). Psychosocial development in survivors of childhood differentiated thyroid carcinoma: A cross-sectional study. European Journal of Endocrinology, 178(3), 215-223. https://doi.org/10.1530/EJE-17-0741
Nies, Marloes ; Dekker, Bernadette L. ; Sulkers, Esther ; Huizinga, Gea A. ; Klein Hesselink, Mariëlle S. ; Maurice-Stam, Heleen ; Grootenhuis, Martha A. ; Brouwers, Adrienne H. ; Burgerhof, Johannes G. M. ; van Dam, Eveline W. C. M. ; Havekes, Bas ; van den Heuvel-Eibrink, Marry M. ; Corssmit, Eleonora P. M. ; Kremer, Leontien C. M. ; Netea-Maier, Romana T. ; van der Pal, Heleen J. H. ; Peeters, Robin P. ; Plukker, John T. M. ; Ronckers, C. cile M. ; van Santen, Hanneke M. ; van der Horst-Schrivers, Anouk N. A. ; Tissing, Wim J. E. ; Bocca, Gianni ; Links, Thera P. / Psychosocial development in survivors of childhood differentiated thyroid carcinoma: A cross-sectional study. In: European Journal of Endocrinology. 2018 ; Vol. 178, No. 3. pp. 215-223.
@article{1c9b980dcbe6487ebb48abe668615fb4,
title = "Psychosocial development in survivors of childhood differentiated thyroid carcinoma: A cross-sectional study",
abstract = "Objective: The impact of childhood differentiated thyroid carcinoma (DTC) on psychosocial development has not yet been studied. The aim of this study was to evaluate the achievement of psychosocial developmental milestones in long-term survivors of childhood DTC. Design and methods: Survivors of childhood DTC diagnosed between 1970 and 2013 were included. Reasons for exclusion were age <18 or >35 years at follow-up, a follow-up period <5 years or diagnosis with DTC as a second malignant neoplasm. Survivors gathered peer controls of similar age and sex (n=30). A comparison group non-affected with cancer (n=508) and other childhood cancer survivors (CCS) were also used to compare psychosocial development. To assess the achievement of psychosocial milestones (social, autonomy and psychosexual development), the course of life questionnaire (CoLQ) was used. Results: We included 39 survivors of childhood DTC (response rate 83.0{\%}, mean age at diagnosis 15.6 years, and mean age at evaluation 26.1 years). CoLQ scores did not significantly differ between survivors of childhood DTC and the two non-affected groups. CoLQ scores of childhood DTC survivors were compared to scores of other CCS diagnosed at similar ages (n= 76). DTC survivors scored significantly higher on social development than other CCS, but scores were similar on autonomy and psychosexual developmental scales. Conclusions: Survivors of childhood DTC showed similar development on social, autonomy, and psychosexual domains compared to non-affected individuals. Social development was slightly more favorable in DTC survivors than in other CCS, but was similar on autonomy and psychosexual domains.",
author = "Marloes Nies and Dekker, {Bernadette L.} and Esther Sulkers and Huizinga, {Gea A.} and {Klein Hesselink}, {Mari{\"e}lle S.} and Heleen Maurice-Stam and Grootenhuis, {Martha A.} and Brouwers, {Adrienne H.} and Burgerhof, {Johannes G. M.} and {van Dam}, {Eveline W. C. M.} and Bas Havekes and {van den Heuvel-Eibrink}, {Marry M.} and Corssmit, {Eleonora P. M.} and Kremer, {Leontien C. M.} and Netea-Maier, {Romana T.} and {van der Pal}, {Heleen J. H.} and Peeters, {Robin P.} and Plukker, {John T. M.} and Ronckers, {C. cile M.} and {van Santen}, {Hanneke M.} and {van der Horst-Schrivers}, {Anouk N. A.} and Tissing, {Wim J. E.} and Gianni Bocca and Links, {Thera P.}",
year = "2018",
doi = "10.1530/EJE-17-0741",
language = "English",
volume = "178",
pages = "215--223",
journal = "European Journal of Endocrinology",
issn = "0804-4643",
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number = "3",

}

Nies, M, Dekker, BL, Sulkers, E, Huizinga, GA, Klein Hesselink, MS, Maurice-Stam, H, Grootenhuis, MA, Brouwers, AH, Burgerhof, JGM, van Dam, EWCM, Havekes, B, van den Heuvel-Eibrink, MM, Corssmit, EPM, Kremer, LCM, Netea-Maier, RT, van der Pal, HJH, Peeters, RP, Plukker, JTM, Ronckers, CCM, van Santen, HM, van der Horst-Schrivers, ANA, Tissing, WJE, Bocca, G & Links, TP 2018, 'Psychosocial development in survivors of childhood differentiated thyroid carcinoma: A cross-sectional study' European Journal of Endocrinology, vol. 178, no. 3, pp. 215-223. https://doi.org/10.1530/EJE-17-0741

Psychosocial development in survivors of childhood differentiated thyroid carcinoma: A cross-sectional study. / Nies, Marloes; Dekker, Bernadette L.; Sulkers, Esther; Huizinga, Gea A.; Klein Hesselink, Mariëlle S.; Maurice-Stam, Heleen; Grootenhuis, Martha A.; Brouwers, Adrienne H.; Burgerhof, Johannes G. M.; van Dam, Eveline W. C. M.; Havekes, Bas; van den Heuvel-Eibrink, Marry M.; Corssmit, Eleonora P. M.; Kremer, Leontien C. M.; Netea-Maier, Romana T.; van der Pal, Heleen J. H.; Peeters, Robin P.; Plukker, John T. M.; Ronckers, C. cile M.; van Santen, Hanneke M.; van der Horst-Schrivers, Anouk N. A.; Tissing, Wim J. E.; Bocca, Gianni; Links, Thera P.

In: European Journal of Endocrinology, Vol. 178, No. 3, 2018, p. 215-223.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - Psychosocial development in survivors of childhood differentiated thyroid carcinoma: A cross-sectional study

AU - Nies, Marloes

AU - Dekker, Bernadette L.

AU - Sulkers, Esther

AU - Huizinga, Gea A.

AU - Klein Hesselink, Mariëlle S.

AU - Maurice-Stam, Heleen

AU - Grootenhuis, Martha A.

AU - Brouwers, Adrienne H.

AU - Burgerhof, Johannes G. M.

AU - van Dam, Eveline W. C. M.

AU - Havekes, Bas

AU - van den Heuvel-Eibrink, Marry M.

AU - Corssmit, Eleonora P. M.

AU - Kremer, Leontien C. M.

AU - Netea-Maier, Romana T.

AU - van der Pal, Heleen J. H.

AU - Peeters, Robin P.

AU - Plukker, John T. M.

AU - Ronckers, C. cile M.

AU - van Santen, Hanneke M.

AU - van der Horst-Schrivers, Anouk N. A.

AU - Tissing, Wim J. E.

AU - Bocca, Gianni

AU - Links, Thera P.

PY - 2018

Y1 - 2018

N2 - Objective: The impact of childhood differentiated thyroid carcinoma (DTC) on psychosocial development has not yet been studied. The aim of this study was to evaluate the achievement of psychosocial developmental milestones in long-term survivors of childhood DTC. Design and methods: Survivors of childhood DTC diagnosed between 1970 and 2013 were included. Reasons for exclusion were age <18 or >35 years at follow-up, a follow-up period <5 years or diagnosis with DTC as a second malignant neoplasm. Survivors gathered peer controls of similar age and sex (n=30). A comparison group non-affected with cancer (n=508) and other childhood cancer survivors (CCS) were also used to compare psychosocial development. To assess the achievement of psychosocial milestones (social, autonomy and psychosexual development), the course of life questionnaire (CoLQ) was used. Results: We included 39 survivors of childhood DTC (response rate 83.0%, mean age at diagnosis 15.6 years, and mean age at evaluation 26.1 years). CoLQ scores did not significantly differ between survivors of childhood DTC and the two non-affected groups. CoLQ scores of childhood DTC survivors were compared to scores of other CCS diagnosed at similar ages (n= 76). DTC survivors scored significantly higher on social development than other CCS, but scores were similar on autonomy and psychosexual developmental scales. Conclusions: Survivors of childhood DTC showed similar development on social, autonomy, and psychosexual domains compared to non-affected individuals. Social development was slightly more favorable in DTC survivors than in other CCS, but was similar on autonomy and psychosexual domains.

AB - Objective: The impact of childhood differentiated thyroid carcinoma (DTC) on psychosocial development has not yet been studied. The aim of this study was to evaluate the achievement of psychosocial developmental milestones in long-term survivors of childhood DTC. Design and methods: Survivors of childhood DTC diagnosed between 1970 and 2013 were included. Reasons for exclusion were age <18 or >35 years at follow-up, a follow-up period <5 years or diagnosis with DTC as a second malignant neoplasm. Survivors gathered peer controls of similar age and sex (n=30). A comparison group non-affected with cancer (n=508) and other childhood cancer survivors (CCS) were also used to compare psychosocial development. To assess the achievement of psychosocial milestones (social, autonomy and psychosexual development), the course of life questionnaire (CoLQ) was used. Results: We included 39 survivors of childhood DTC (response rate 83.0%, mean age at diagnosis 15.6 years, and mean age at evaluation 26.1 years). CoLQ scores did not significantly differ between survivors of childhood DTC and the two non-affected groups. CoLQ scores of childhood DTC survivors were compared to scores of other CCS diagnosed at similar ages (n= 76). DTC survivors scored significantly higher on social development than other CCS, but scores were similar on autonomy and psychosexual developmental scales. Conclusions: Survivors of childhood DTC showed similar development on social, autonomy, and psychosexual domains compared to non-affected individuals. Social development was slightly more favorable in DTC survivors than in other CCS, but was similar on autonomy and psychosexual domains.

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UR - https://www.ncbi.nlm.nih.gov/pubmed/29254931

U2 - 10.1530/EJE-17-0741

DO - 10.1530/EJE-17-0741

M3 - Article

VL - 178

SP - 215

EP - 223

JO - European Journal of Endocrinology

JF - European Journal of Endocrinology

SN - 0804-4643

IS - 3

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