Psychosocial risk factors and the metabolic syndrome in elderly persons: Findings from the health, aging and body composition study

Nicole Vogelzangs, Aartjan T.F. Beekman, Stephen B. Kritchevsky, Anne B. Newman, Marco Pahor, Kristine Yaffe, Susan M. Rubin, Tamara B. Harris, Suzanne Satterfield, Eleanor M. Simonsick, Brenda W.J.H. Penninx

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Background. Psychosocial factors have been associated with metabolic abnormalities that increase the risk of cardiovascular disease and diabetes. This study investigated the cross-sectional relationship between psychosocial risk factors and the metabolic syndrome in a community-based sample of older persons. Methods. Participants were 2917 persons aged 70-79 years enrolled in the Health, Aging and Body Composition study. Depressive and anxiety symptoms, negative life events, and inadequate emotional support were assessed, and a summary psychosocial risk index was calculated. Metabolic syndrome was defined as three or more of the following criteria: abdominal obesity, high triglycerides, low high-density lipoprotein (HDL) cholesterol, high fasting glucose, and high blood pressure. Results. Negative life events and inadequate emotional support increased the odds of having metabolic syndrome after adjustment for demographic and lifestyle variables (odds ratio [OR] per life event = 1.13, 95% confidence interval [CI] = 1.05-1.22; OR = 1.35, 95% CI = 1.10-1.66, respectively). The relationship between depressive symptoms and metabolic syndrome was only found in white (OR per standard deviation [SD]= 1.11, 95% CI = 1.01-1.23), but not in black (OR per SD = 0.97, 95% CI = 0.86-1.11) persons. Anxiety symptoms were significantly associated with metabolic syndrome in men (OR per SD = 1.13, 95% CI = 1.00-1.28), but not in women (OR per SD = 0.98, 95% CI = 0.89-1.08). Moreover, a higher score on the psychosocial risk index was associated with an increased probability of having the metabolic syndrome (OR = 1.30, 95% CI = 1.12-1.52). Conclusions. In the elderly population, different psychosocial risk factors are associated with a higher prevalence of the metabolic syndrome. Whether reduction or better management of psychosocial risk factors can improve the metabolic profile remains to be demonstrated.

Original languageEnglish
Pages (from-to)563-569
Number of pages7
JournalJournals of Gerontology - Series A Biological Sciences and Medical Sciences
Volume62
Issue number5
DOIs
Publication statusPublished - 1 Jan 2007

Cite this

Vogelzangs, Nicole ; Beekman, Aartjan T.F. ; Kritchevsky, Stephen B. ; Newman, Anne B. ; Pahor, Marco ; Yaffe, Kristine ; Rubin, Susan M. ; Harris, Tamara B. ; Satterfield, Suzanne ; Simonsick, Eleanor M. ; Penninx, Brenda W.J.H. / Psychosocial risk factors and the metabolic syndrome in elderly persons : Findings from the health, aging and body composition study. In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 2007 ; Vol. 62, No. 5. pp. 563-569.
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title = "Psychosocial risk factors and the metabolic syndrome in elderly persons: Findings from the health, aging and body composition study",
abstract = "Background. Psychosocial factors have been associated with metabolic abnormalities that increase the risk of cardiovascular disease and diabetes. This study investigated the cross-sectional relationship between psychosocial risk factors and the metabolic syndrome in a community-based sample of older persons. Methods. Participants were 2917 persons aged 70-79 years enrolled in the Health, Aging and Body Composition study. Depressive and anxiety symptoms, negative life events, and inadequate emotional support were assessed, and a summary psychosocial risk index was calculated. Metabolic syndrome was defined as three or more of the following criteria: abdominal obesity, high triglycerides, low high-density lipoprotein (HDL) cholesterol, high fasting glucose, and high blood pressure. Results. Negative life events and inadequate emotional support increased the odds of having metabolic syndrome after adjustment for demographic and lifestyle variables (odds ratio [OR] per life event = 1.13, 95{\%} confidence interval [CI] = 1.05-1.22; OR = 1.35, 95{\%} CI = 1.10-1.66, respectively). The relationship between depressive symptoms and metabolic syndrome was only found in white (OR per standard deviation [SD]= 1.11, 95{\%} CI = 1.01-1.23), but not in black (OR per SD = 0.97, 95{\%} CI = 0.86-1.11) persons. Anxiety symptoms were significantly associated with metabolic syndrome in men (OR per SD = 1.13, 95{\%} CI = 1.00-1.28), but not in women (OR per SD = 0.98, 95{\%} CI = 0.89-1.08). Moreover, a higher score on the psychosocial risk index was associated with an increased probability of having the metabolic syndrome (OR = 1.30, 95{\%} CI = 1.12-1.52). Conclusions. In the elderly population, different psychosocial risk factors are associated with a higher prevalence of the metabolic syndrome. Whether reduction or better management of psychosocial risk factors can improve the metabolic profile remains to be demonstrated.",
author = "Nicole Vogelzangs and Beekman, {Aartjan T.F.} and Kritchevsky, {Stephen B.} and Newman, {Anne B.} and Marco Pahor and Kristine Yaffe and Rubin, {Susan M.} and Harris, {Tamara B.} and Suzanne Satterfield and Simonsick, {Eleanor M.} and Penninx, {Brenda W.J.H.}",
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Psychosocial risk factors and the metabolic syndrome in elderly persons : Findings from the health, aging and body composition study. / Vogelzangs, Nicole; Beekman, Aartjan T.F.; Kritchevsky, Stephen B.; Newman, Anne B.; Pahor, Marco; Yaffe, Kristine; Rubin, Susan M.; Harris, Tamara B.; Satterfield, Suzanne; Simonsick, Eleanor M.; Penninx, Brenda W.J.H.

In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences, Vol. 62, No. 5, 01.01.2007, p. 563-569.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - Psychosocial risk factors and the metabolic syndrome in elderly persons

T2 - Findings from the health, aging and body composition study

AU - Vogelzangs, Nicole

AU - Beekman, Aartjan T.F.

AU - Kritchevsky, Stephen B.

AU - Newman, Anne B.

AU - Pahor, Marco

AU - Yaffe, Kristine

AU - Rubin, Susan M.

AU - Harris, Tamara B.

AU - Satterfield, Suzanne

AU - Simonsick, Eleanor M.

AU - Penninx, Brenda W.J.H.

PY - 2007/1/1

Y1 - 2007/1/1

N2 - Background. Psychosocial factors have been associated with metabolic abnormalities that increase the risk of cardiovascular disease and diabetes. This study investigated the cross-sectional relationship between psychosocial risk factors and the metabolic syndrome in a community-based sample of older persons. Methods. Participants were 2917 persons aged 70-79 years enrolled in the Health, Aging and Body Composition study. Depressive and anxiety symptoms, negative life events, and inadequate emotional support were assessed, and a summary psychosocial risk index was calculated. Metabolic syndrome was defined as three or more of the following criteria: abdominal obesity, high triglycerides, low high-density lipoprotein (HDL) cholesterol, high fasting glucose, and high blood pressure. Results. Negative life events and inadequate emotional support increased the odds of having metabolic syndrome after adjustment for demographic and lifestyle variables (odds ratio [OR] per life event = 1.13, 95% confidence interval [CI] = 1.05-1.22; OR = 1.35, 95% CI = 1.10-1.66, respectively). The relationship between depressive symptoms and metabolic syndrome was only found in white (OR per standard deviation [SD]= 1.11, 95% CI = 1.01-1.23), but not in black (OR per SD = 0.97, 95% CI = 0.86-1.11) persons. Anxiety symptoms were significantly associated with metabolic syndrome in men (OR per SD = 1.13, 95% CI = 1.00-1.28), but not in women (OR per SD = 0.98, 95% CI = 0.89-1.08). Moreover, a higher score on the psychosocial risk index was associated with an increased probability of having the metabolic syndrome (OR = 1.30, 95% CI = 1.12-1.52). Conclusions. In the elderly population, different psychosocial risk factors are associated with a higher prevalence of the metabolic syndrome. Whether reduction or better management of psychosocial risk factors can improve the metabolic profile remains to be demonstrated.

AB - Background. Psychosocial factors have been associated with metabolic abnormalities that increase the risk of cardiovascular disease and diabetes. This study investigated the cross-sectional relationship between psychosocial risk factors and the metabolic syndrome in a community-based sample of older persons. Methods. Participants were 2917 persons aged 70-79 years enrolled in the Health, Aging and Body Composition study. Depressive and anxiety symptoms, negative life events, and inadequate emotional support were assessed, and a summary psychosocial risk index was calculated. Metabolic syndrome was defined as three or more of the following criteria: abdominal obesity, high triglycerides, low high-density lipoprotein (HDL) cholesterol, high fasting glucose, and high blood pressure. Results. Negative life events and inadequate emotional support increased the odds of having metabolic syndrome after adjustment for demographic and lifestyle variables (odds ratio [OR] per life event = 1.13, 95% confidence interval [CI] = 1.05-1.22; OR = 1.35, 95% CI = 1.10-1.66, respectively). The relationship between depressive symptoms and metabolic syndrome was only found in white (OR per standard deviation [SD]= 1.11, 95% CI = 1.01-1.23), but not in black (OR per SD = 0.97, 95% CI = 0.86-1.11) persons. Anxiety symptoms were significantly associated with metabolic syndrome in men (OR per SD = 1.13, 95% CI = 1.00-1.28), but not in women (OR per SD = 0.98, 95% CI = 0.89-1.08). Moreover, a higher score on the psychosocial risk index was associated with an increased probability of having the metabolic syndrome (OR = 1.30, 95% CI = 1.12-1.52). Conclusions. In the elderly population, different psychosocial risk factors are associated with a higher prevalence of the metabolic syndrome. Whether reduction or better management of psychosocial risk factors can improve the metabolic profile remains to be demonstrated.

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U2 - 10.1093/gerona/62.5.563

DO - 10.1093/gerona/62.5.563

M3 - Article

VL - 62

SP - 563

EP - 569

JO - Journals of Gerontology. Series A: Biological Sciences & Medical Sciences

JF - Journals of Gerontology. Series A: Biological Sciences & Medical Sciences

SN - 1079-5006

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