Quality of life and psychosocial outcomes in children with severe acute asthma and their parents

Shelley A. Boeschoten*, Karolijn Dulfer, Annemie L.M. Boehmer, Peter J.F.M. Merkus, Joost van Rosmalen, Johan C. de Jongste, Matthijs de Hoog, Corinne M.P. Buysse, Sabien Heisterkamp, Job van Woensel, Eric Haarman, Berber Kapitein, Roelie Wösten-van Asperen, Martin Kneyber, Joris Lemson, Stan Hartman, Dick van Waardenburg, Heleen Bunker, Carole Brouwer, Bart van EwijkAnneke Landstra, Mariel Verwaal, Anja Vaessen-Verberne, Sanne Hammer, the Dutch collaborative PICU research network (SKIC)

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Objectives: To prospectively evaluate quality of life (QoL) and psychosocial outcomes in children with severe acute asthma (SAA) after pediatric intensive care (PICU) admission compared to children with SAA who were admitted to a general ward (GW). In addition, we assessed posttraumatic stress (PTS) and asthma-related QoL in the parents. Methods: A preplanned follow-up of 3 to 9 months of our nationwide prospective multicenter study, in which children with SAA admitted to a Dutch PICU (n = 110) or GW (n = 111) were enrolled between 2016 and 2018. Asthma-related QoL, PTS symptoms, emotional and behavioral problems, and social impact in children and/or parents were assessed with validated web-based questionnaires. Results: We included 100 children after PICU and 103 after GW admission, with a response rate of 50% for the questionnaires. Median time to follow-up was 5 months (range: 1-12 months). Time to reach full schooldays after admission was significantly longer in the PICU group (mean of 10 vs 4 days, P =.001). Parents in the PICU group reported more PTS symptoms (intrusion P =.01, avoidance P =.01, arousal P =.02) compared to the GW group. Conclusion: No significant differences were found between PICU and GW children on self-reported outcome domains, except for the time to reach full schooldays. PICU parents reported PTS symptoms more often than the GW group. Therefore, monitoring asthma symptoms and psychosocial screening of children and parents after PICU admission should both be part of standard care after SAA. This should identify those who are at risk for developing PTSD, to timely provide appropriate interventions.

Original languageEnglish
Pages (from-to)2883-2892
Number of pages10
JournalPediatric Pulmonology
Volume55
Issue number11
DOIs
Publication statusPublished - 1 Nov 2020

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