Quantitative Issues in Response Measurement by PET

Research output: Contribution to journalReview articleAcademicpeer-review

Abstract

Monitoring response to anticancer therapy requires a (semi)quantitative PET approach. In this review, several instrumentation and analysis issues that have an impact on quantification are discussed. These issues are divided into the following steps: data acquisition, image reconstruction, image analysis, and data analysis. Although the focus of this review is on FDG, most issues presented apply to all tracers (ie, to PET quantification in general).

Original languageEnglish
Pages (from-to)5-11
Number of pages7
JournalPET Clinics
Volume3
Issue number1
DOIs
Publication statusPublished - 1 Jan 2008

Cite this

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title = "Quantitative Issues in Response Measurement by PET",
abstract = "Monitoring response to anticancer therapy requires a (semi)quantitative PET approach. In this review, several instrumentation and analysis issues that have an impact on quantification are discussed. These issues are divided into the following steps: data acquisition, image reconstruction, image analysis, and data analysis. Although the focus of this review is on FDG, most issues presented apply to all tracers (ie, to PET quantification in general).",
keywords = "FDG, PET, Quantification, Response monitoring, Tracer kinetic modeling",
author = "Lammertsma, {Adriaan A.} and Ronald Boellaard and Hoekstra, {Otto S.}",
year = "2008",
month = "1",
day = "1",
doi = "10.1016/j.cpet.2008.08.003",
language = "English",
volume = "3",
pages = "5--11",
journal = "Clinics in Geriatric Medicine",
issn = "0749-0690",
publisher = "W.B. Saunders Ltd",
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}

Quantitative Issues in Response Measurement by PET. / Lammertsma, Adriaan A.; Boellaard, Ronald; Hoekstra, Otto S.

In: PET Clinics, Vol. 3, No. 1, 01.01.2008, p. 5-11.

Research output: Contribution to journalReview articleAcademicpeer-review

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AU - Lammertsma, Adriaan A.

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AU - Hoekstra, Otto S.

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AB - Monitoring response to anticancer therapy requires a (semi)quantitative PET approach. In this review, several instrumentation and analysis issues that have an impact on quantification are discussed. These issues are divided into the following steps: data acquisition, image reconstruction, image analysis, and data analysis. Although the focus of this review is on FDG, most issues presented apply to all tracers (ie, to PET quantification in general).

KW - FDG

KW - PET

KW - Quantification

KW - Response monitoring

KW - Tracer kinetic modeling

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