Quantitative Issues in Response Measurement by PET

Adriaan A. Lammertsma; Ronald Boellaard; Otto S. Hoekstra

doi:10.1016/j.cpet.2008.08.003

Quantitative Issues in Response Measurement by PET

Adriaan A. Lammertsma^*, Ronald Boellaard, Otto S. Hoekstra

^*Corresponding author for this work

Radiology and nuclear medicine

Research output: Contribution to journal › Review article › Academic › peer-review

Abstract

Monitoring response to anticancer therapy requires a (semi)quantitative PET approach. In this review, several instrumentation and analysis issues that have an impact on quantification are discussed. These issues are divided into the following steps: data acquisition, image reconstruction, image analysis, and data analysis. Although the focus of this review is on FDG, most issues presented apply to all tracers (ie, to PET quantification in general).

Original language	English
Pages (from-to)	5-11
Number of pages	7
Journal	PET Clinics
Volume	3
Issue number	1
DOIs	https://doi.org/10.1016/j.cpet.2008.08.003
Publication status	Published - 1 Jan 2008

Access to Document

10.1016/j.cpet.2008.08.003

Cite this

@article{97ca91162a324361bd11533d68d21d10,

title = "Quantitative Issues in Response Measurement by PET",

abstract = "Monitoring response to anticancer therapy requires a (semi)quantitative PET approach. In this review, several instrumentation and analysis issues that have an impact on quantification are discussed. These issues are divided into the following steps: data acquisition, image reconstruction, image analysis, and data analysis. Although the focus of this review is on FDG, most issues presented apply to all tracers (ie, to PET quantification in general).",

keywords = "FDG, PET, Quantification, Response monitoring, Tracer kinetic modeling",

author = "Lammertsma, {Adriaan A.} and Ronald Boellaard and Hoekstra, {Otto S.}",

year = "2008",

month = jan,

day = "1",

doi = "10.1016/j.cpet.2008.08.003",

language = "English",

volume = "3",

pages = "5--11",

journal = "Clinics in Geriatric Medicine",

issn = "0749-0690",

publisher = "W.B. Saunders Ltd",

number = "1",

}

TY - JOUR

T1 - Quantitative Issues in Response Measurement by PET

AU - Lammertsma, Adriaan A.

AU - Boellaard, Ronald

AU - Hoekstra, Otto S.

PY - 2008/1/1

Y1 - 2008/1/1

N2 - Monitoring response to anticancer therapy requires a (semi)quantitative PET approach. In this review, several instrumentation and analysis issues that have an impact on quantification are discussed. These issues are divided into the following steps: data acquisition, image reconstruction, image analysis, and data analysis. Although the focus of this review is on FDG, most issues presented apply to all tracers (ie, to PET quantification in general).

AB - Monitoring response to anticancer therapy requires a (semi)quantitative PET approach. In this review, several instrumentation and analysis issues that have an impact on quantification are discussed. These issues are divided into the following steps: data acquisition, image reconstruction, image analysis, and data analysis. Although the focus of this review is on FDG, most issues presented apply to all tracers (ie, to PET quantification in general).

KW - FDG

KW - PET

KW - Quantification

KW - Response monitoring

KW - Tracer kinetic modeling

UR - http://www.scopus.com/inward/record.url?scp=64749110672&partnerID=8YFLogxK

U2 - 10.1016/j.cpet.2008.08.003

DO - 10.1016/j.cpet.2008.08.003

M3 - Review article

AN - SCOPUS:64749110672

SN - 0749-0690

VL - 3

SP - 5

EP - 11

JO - Clinics in Geriatric Medicine

JF - Clinics in Geriatric Medicine

IS - 1

ER -

Quantitative Issues in Response Measurement by PET

Abstract

Access to Document

Other files and links

Cite this