Radiographic Axial Malalignment is Associated With Pretreatment Patient-Reported Health-Related Quality of Life Measures in Adult Degenerative Scoliosis: Implementation of a Novel Radiographic Software Tool

European Spine Study Group

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Study Design: Retrospective study of prospectively collected data. Objectives: The purpose of this study was to evaluate the relationship between apical vertebral axial rotation and pretreatment patient-reported health-related quality of life (HRQOL), disability, and pain in patients with adult degenerative scoliosis (ADS) using a novel radiographic software tool. Summary of Background Data: Recent studies have demonstrated that in ADS, sagittal and coronal plane deformity are weakly to moderately associated with HRQOL, disability, and pain. However, as ADS is a three-dimensional spinal deformity, the impact of axial malalignment on HRQOL is yet to be determined. Methods: A total of 74 ADS patients were enrolled. HRQOL measures included the Short Form-36v2 (SF-36v2) and Scoliosis Research Society questionnaire (SRS-22r). Disability and pain measures included the Oswestry Disability Index (ODI) and numeric rating scale back and leg pain. Radiographic measures included Cobb angle (CA), sagittal spinopelvic parameters, lateral and anteroposterior (AP) translation of the apical vertebra. The amount of apical vertebral axial rotation was measured on digital AP radiograph images using a novel software technology. Subjects were stratified into four clinical groups based on the degree of apical vertebral axial rotation. Results: Apical vertebral axial rotation showed no association with lateral (r = 0.21; p =.15) and AP (r = 0.08, p =.80) translation of the apical vertebra. A significant moderate association was found between apical vertebral axial rotation and Cobb angle (r = 0.57; p <.05). Patients in the group with the highest degree of apical vertebral axial rotation reported significantly worse ODI and SRS-22r Subtotal and Pain scores (p <.05), irrespective of sagittal spinopelvic parameters. Conclusions: This is the first study that reports on the association between apical vertebral axial rotation and pretreatment HRQOL, disability, and pain in ADS. This study suggests that increased apical vertebral axial rotation is associated with suboptimal pretreatment health status scores. Level of Evidence: Level III.
Original languageEnglish
Pages (from-to)745-752
JournalSpine Deformity
Volume6
Issue number6
DOIs
Publication statusPublished - 2018

Cite this

@article{95b7dbb7c4a245fbbb89bf7daa87de7d,
title = "Radiographic Axial Malalignment is Associated With Pretreatment Patient-Reported Health-Related Quality of Life Measures in Adult Degenerative Scoliosis: Implementation of a Novel Radiographic Software Tool",
abstract = "Study Design: Retrospective study of prospectively collected data. Objectives: The purpose of this study was to evaluate the relationship between apical vertebral axial rotation and pretreatment patient-reported health-related quality of life (HRQOL), disability, and pain in patients with adult degenerative scoliosis (ADS) using a novel radiographic software tool. Summary of Background Data: Recent studies have demonstrated that in ADS, sagittal and coronal plane deformity are weakly to moderately associated with HRQOL, disability, and pain. However, as ADS is a three-dimensional spinal deformity, the impact of axial malalignment on HRQOL is yet to be determined. Methods: A total of 74 ADS patients were enrolled. HRQOL measures included the Short Form-36v2 (SF-36v2) and Scoliosis Research Society questionnaire (SRS-22r). Disability and pain measures included the Oswestry Disability Index (ODI) and numeric rating scale back and leg pain. Radiographic measures included Cobb angle (CA), sagittal spinopelvic parameters, lateral and anteroposterior (AP) translation of the apical vertebra. The amount of apical vertebral axial rotation was measured on digital AP radiograph images using a novel software technology. Subjects were stratified into four clinical groups based on the degree of apical vertebral axial rotation. Results: Apical vertebral axial rotation showed no association with lateral (r = 0.21; p =.15) and AP (r = 0.08, p =.80) translation of the apical vertebra. A significant moderate association was found between apical vertebral axial rotation and Cobb angle (r = 0.57; p <.05). Patients in the group with the highest degree of apical vertebral axial rotation reported significantly worse ODI and SRS-22r Subtotal and Pain scores (p <.05), irrespective of sagittal spinopelvic parameters. Conclusions: This is the first study that reports on the association between apical vertebral axial rotation and pretreatment HRQOL, disability, and pain in ADS. This study suggests that increased apical vertebral axial rotation is associated with suboptimal pretreatment health status scores. Level of Evidence: Level III.",
author = "{European Spine Study Group} and Faraj, {Sayf S. A.} and Boselie, {Toon F. M.} and Alba Vila-Casademunt and {de Kleuver}, Marinus and Holewijn, {Roderick M.} and Ibrahim Obeid and Emre Acaroglu and Ahmet Alanay and Frank Kleinst{\"u}ck and P{\'e}rez-Grueso, {Francisco S.} and Ferran Pellis{\'e}",
year = "2018",
doi = "10.1016/j.jspd.2018.03.011",
language = "English",
volume = "6",
pages = "745--752",
journal = "Spine Deformity",
issn = "2212-134X",
publisher = "Elsevier BV",
number = "6",

}

Radiographic Axial Malalignment is Associated With Pretreatment Patient-Reported Health-Related Quality of Life Measures in Adult Degenerative Scoliosis: Implementation of a Novel Radiographic Software Tool. / European Spine Study Group.

In: Spine Deformity, Vol. 6, No. 6, 2018, p. 745-752.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - Radiographic Axial Malalignment is Associated With Pretreatment Patient-Reported Health-Related Quality of Life Measures in Adult Degenerative Scoliosis: Implementation of a Novel Radiographic Software Tool

AU - European Spine Study Group

AU - Faraj, Sayf S. A.

AU - Boselie, Toon F. M.

AU - Vila-Casademunt, Alba

AU - de Kleuver, Marinus

AU - Holewijn, Roderick M.

AU - Obeid, Ibrahim

AU - Acaroglu, Emre

AU - Alanay, Ahmet

AU - Kleinstück, Frank

AU - Pérez-Grueso, Francisco S.

AU - Pellisé, Ferran

PY - 2018

Y1 - 2018

N2 - Study Design: Retrospective study of prospectively collected data. Objectives: The purpose of this study was to evaluate the relationship between apical vertebral axial rotation and pretreatment patient-reported health-related quality of life (HRQOL), disability, and pain in patients with adult degenerative scoliosis (ADS) using a novel radiographic software tool. Summary of Background Data: Recent studies have demonstrated that in ADS, sagittal and coronal plane deformity are weakly to moderately associated with HRQOL, disability, and pain. However, as ADS is a three-dimensional spinal deformity, the impact of axial malalignment on HRQOL is yet to be determined. Methods: A total of 74 ADS patients were enrolled. HRQOL measures included the Short Form-36v2 (SF-36v2) and Scoliosis Research Society questionnaire (SRS-22r). Disability and pain measures included the Oswestry Disability Index (ODI) and numeric rating scale back and leg pain. Radiographic measures included Cobb angle (CA), sagittal spinopelvic parameters, lateral and anteroposterior (AP) translation of the apical vertebra. The amount of apical vertebral axial rotation was measured on digital AP radiograph images using a novel software technology. Subjects were stratified into four clinical groups based on the degree of apical vertebral axial rotation. Results: Apical vertebral axial rotation showed no association with lateral (r = 0.21; p =.15) and AP (r = 0.08, p =.80) translation of the apical vertebra. A significant moderate association was found between apical vertebral axial rotation and Cobb angle (r = 0.57; p <.05). Patients in the group with the highest degree of apical vertebral axial rotation reported significantly worse ODI and SRS-22r Subtotal and Pain scores (p <.05), irrespective of sagittal spinopelvic parameters. Conclusions: This is the first study that reports on the association between apical vertebral axial rotation and pretreatment HRQOL, disability, and pain in ADS. This study suggests that increased apical vertebral axial rotation is associated with suboptimal pretreatment health status scores. Level of Evidence: Level III.

AB - Study Design: Retrospective study of prospectively collected data. Objectives: The purpose of this study was to evaluate the relationship between apical vertebral axial rotation and pretreatment patient-reported health-related quality of life (HRQOL), disability, and pain in patients with adult degenerative scoliosis (ADS) using a novel radiographic software tool. Summary of Background Data: Recent studies have demonstrated that in ADS, sagittal and coronal plane deformity are weakly to moderately associated with HRQOL, disability, and pain. However, as ADS is a three-dimensional spinal deformity, the impact of axial malalignment on HRQOL is yet to be determined. Methods: A total of 74 ADS patients were enrolled. HRQOL measures included the Short Form-36v2 (SF-36v2) and Scoliosis Research Society questionnaire (SRS-22r). Disability and pain measures included the Oswestry Disability Index (ODI) and numeric rating scale back and leg pain. Radiographic measures included Cobb angle (CA), sagittal spinopelvic parameters, lateral and anteroposterior (AP) translation of the apical vertebra. The amount of apical vertebral axial rotation was measured on digital AP radiograph images using a novel software technology. Subjects were stratified into four clinical groups based on the degree of apical vertebral axial rotation. Results: Apical vertebral axial rotation showed no association with lateral (r = 0.21; p =.15) and AP (r = 0.08, p =.80) translation of the apical vertebra. A significant moderate association was found between apical vertebral axial rotation and Cobb angle (r = 0.57; p <.05). Patients in the group with the highest degree of apical vertebral axial rotation reported significantly worse ODI and SRS-22r Subtotal and Pain scores (p <.05), irrespective of sagittal spinopelvic parameters. Conclusions: This is the first study that reports on the association between apical vertebral axial rotation and pretreatment HRQOL, disability, and pain in ADS. This study suggests that increased apical vertebral axial rotation is associated with suboptimal pretreatment health status scores. Level of Evidence: Level III.

UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85046686110&origin=inward

UR - https://www.ncbi.nlm.nih.gov/pubmed/30348354

U2 - 10.1016/j.jspd.2018.03.011

DO - 10.1016/j.jspd.2018.03.011

M3 - Article

VL - 6

SP - 745

EP - 752

JO - Spine Deformity

JF - Spine Deformity

SN - 2212-134X

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ER -