Radiotherapy-induced cerebral abnormalities in patients with low-grade glioma

T. J. Postma, M. Klein, C. C.P. Verstappen, J. E.C. Bromberg, M. Swennen, J. A. Langendijk, M. J.B. Taphoorn, P. Scheltens, B. J. Slotman, H. M. Van der Ploeg, N. K. Aaronson, J. J. Heimans

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Abnormalities on CT or MRI and neuropsychological performance in patients with low-grade glioma, with (n = 23) or without (n = 16) prior cerebral radiotherapy, were evaluated. Cerebral atrophy was observed in 14 of 23 patients (61%) treated with prior radiotherapy, and in 1 of 16 patients (6%) without prior radiotherapy. White matter abnormalities were observed in six patients, all of whom were treated with prior radiotherapy. These radiologic cerebral abnormalities correlated with cognitive performance.
Original languageEnglish
Pages (from-to)121-123
Number of pages3
JournalNeurology
Volume59
Issue number1
DOIs
Publication statusPublished - 9 Jul 2002

Cite this

Postma, T. J., Klein, M., Verstappen, C. C. P., Bromberg, J. E. C., Swennen, M., Langendijk, J. A., ... Heimans, J. J. (2002). Radiotherapy-induced cerebral abnormalities in patients with low-grade glioma. Neurology, 59(1), 121-123. https://doi.org/10.1212/WNL.59.1.121
Postma, T. J. ; Klein, M. ; Verstappen, C. C.P. ; Bromberg, J. E.C. ; Swennen, M. ; Langendijk, J. A. ; Taphoorn, M. J.B. ; Scheltens, P. ; Slotman, B. J. ; Van der Ploeg, H. M. ; Aaronson, N. K. ; Heimans, J. J. / Radiotherapy-induced cerebral abnormalities in patients with low-grade glioma. In: Neurology. 2002 ; Vol. 59, No. 1. pp. 121-123.
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title = "Radiotherapy-induced cerebral abnormalities in patients with low-grade glioma",
abstract = "Abnormalities on CT or MRI and neuropsychological performance in patients with low-grade glioma, with (n = 23) or without (n = 16) prior cerebral radiotherapy, were evaluated. Cerebral atrophy was observed in 14 of 23 patients (61{\%}) treated with prior radiotherapy, and in 1 of 16 patients (6{\%}) without prior radiotherapy. White matter abnormalities were observed in six patients, all of whom were treated with prior radiotherapy. These radiologic cerebral abnormalities correlated with cognitive performance.",
author = "Postma, {T. J.} and M. Klein and Verstappen, {C. C.P.} and Bromberg, {J. E.C.} and M. Swennen and Langendijk, {J. A.} and Taphoorn, {M. J.B.} and P. Scheltens and Slotman, {B. J.} and {Van der Ploeg}, {H. M.} and Aaronson, {N. K.} and Heimans, {J. J.}",
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Postma, TJ, Klein, M, Verstappen, CCP, Bromberg, JEC, Swennen, M, Langendijk, JA, Taphoorn, MJB, Scheltens, P, Slotman, BJ, Van der Ploeg, HM, Aaronson, NK & Heimans, JJ 2002, 'Radiotherapy-induced cerebral abnormalities in patients with low-grade glioma' Neurology, vol. 59, no. 1, pp. 121-123. https://doi.org/10.1212/WNL.59.1.121

Radiotherapy-induced cerebral abnormalities in patients with low-grade glioma. / Postma, T. J.; Klein, M.; Verstappen, C. C.P.; Bromberg, J. E.C.; Swennen, M.; Langendijk, J. A.; Taphoorn, M. J.B.; Scheltens, P.; Slotman, B. J.; Van der Ploeg, H. M.; Aaronson, N. K.; Heimans, J. J.

In: Neurology, Vol. 59, No. 1, 09.07.2002, p. 121-123.

Research output: Contribution to journalArticleAcademicpeer-review

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T1 - Radiotherapy-induced cerebral abnormalities in patients with low-grade glioma

AU - Postma, T. J.

AU - Klein, M.

AU - Verstappen, C. C.P.

AU - Bromberg, J. E.C.

AU - Swennen, M.

AU - Langendijk, J. A.

AU - Taphoorn, M. J.B.

AU - Scheltens, P.

AU - Slotman, B. J.

AU - Van der Ploeg, H. M.

AU - Aaronson, N. K.

AU - Heimans, J. J.

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AB - Abnormalities on CT or MRI and neuropsychological performance in patients with low-grade glioma, with (n = 23) or without (n = 16) prior cerebral radiotherapy, were evaluated. Cerebral atrophy was observed in 14 of 23 patients (61%) treated with prior radiotherapy, and in 1 of 16 patients (6%) without prior radiotherapy. White matter abnormalities were observed in six patients, all of whom were treated with prior radiotherapy. These radiologic cerebral abnormalities correlated with cognitive performance.

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Postma TJ, Klein M, Verstappen CCP, Bromberg JEC, Swennen M, Langendijk JA et al. Radiotherapy-induced cerebral abnormalities in patients with low-grade glioma. Neurology. 2002 Jul 9;59(1):121-123. https://doi.org/10.1212/WNL.59.1.121