Rapid brain death caused by a cerebellar abscess with Fusobacterium nucleatum in a young man with drug abuse: a case report

Gunnar T R Hischebeth, Vera C Keil, Katrin Gentil, Azize Boström, Klaus Kuchelmeister, Isabelle Bekeredjian-Ding

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

BACKGROUND: Fusobacterium nucleatum is a strict anaerobic microorganism that causes disease entities such as periodontal and soft tissue abscesses, pulmonary and intraabdominal infections and very rarely intracerebral infections.

CASE PRESENTATION: Here, we report the rare case of a previously healthy 25-year-old German man with a cerebellar abscess caused by Fusobacterium nucleatum that resulted in rapid brain death. Toxicological screening showed positivity for amphetamines and cannabis. The diagnosis was obtained by polymerase chain reaction amplification of bacterial deoxyribonucleic acid in cerebrospinal fluid.

CONCLUSIONS: In drug users clinicians should think about rare causes of brain abscesses/meningitis. Early diagnosis is necessary and justifies the use of molecular techniques.

Original languageEnglish
Pages (from-to)353
JournalBMC Research Notes
Volume7
DOIs
Publication statusPublished - 10 Jun 2014

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