TY - JOUR
T1 - Reliability and validity of a new dexterity questionnaire (DextQ-24) in Parkinson's disease
AU - Vanbellingen, Tim
AU - Nyffeler, Thomas
AU - Nef, Tobias
AU - Kwakkel, Gert
AU - Bohlhalter, Stephan
AU - van Wegen, Erwin E H
N1 - Copyright © 2016 Elsevier Ltd. All rights reserved.
PY - 2016/12/1
Y1 - 2016/12/1
N2 - BACKGROUND: Patients with Parkinson's disease exhibit disturbed dexterity. Validated self-reported outcomes for dexterity in Parkinson's disease are lacking. The aim of this study was to investigate the reliability, content and construct validity of a new Dexterity Questionnaire 24.METHODS: One hundred and three patients with Parkinson's disease completed the Dexterity Questionnaire 24 (score range 24-96), at baseline and four weeks later. The internal consistency was determined. Test-retest reliability was assessed in a subgroup (N = 44). Standard error of measurements and the minimal detectable change were defined. The construct validity was examined in the whole group (N = 103). Floor and ceiling effects were investigated.RESULTS: The internal consistency of the Dexterity Questionnaire 24 was high (α = 0.91). High test-retest reliability was found (Intra Class Correlation Coefficient = 0.91, Confidence interval: 0.84-0.95). Standard error of measurement was 2.9 and minimal detectable change was 8 points. (i.e., 11%). Good structural, convergent and divergent validity of the Dexterity questionnaire 24 was found (r = 0.73 with Activities of Daily Living-subscale of the Parkinson's Disease Questionnaire-39, and r = 0.66, and r = 0.50, p-values all < 0.0001, respectively with the subscales II and III of the Movement Disorders Society-Unified Parkinson Disease Rating Scale). Low not significant correlations were found between the Dexterity Questionnaire 24 and the subscales stigma and social support (r = 0.20, and r = 0.14 respectively). No floor or ceiling effects were found for the total Dexterity Questionnaire 24.CONCLUSION: The Dexterity Questionnaire 24 is valid and reliable for evaluating dexterity in patients with Parkinson's disease.
AB - BACKGROUND: Patients with Parkinson's disease exhibit disturbed dexterity. Validated self-reported outcomes for dexterity in Parkinson's disease are lacking. The aim of this study was to investigate the reliability, content and construct validity of a new Dexterity Questionnaire 24.METHODS: One hundred and three patients with Parkinson's disease completed the Dexterity Questionnaire 24 (score range 24-96), at baseline and four weeks later. The internal consistency was determined. Test-retest reliability was assessed in a subgroup (N = 44). Standard error of measurements and the minimal detectable change were defined. The construct validity was examined in the whole group (N = 103). Floor and ceiling effects were investigated.RESULTS: The internal consistency of the Dexterity Questionnaire 24 was high (α = 0.91). High test-retest reliability was found (Intra Class Correlation Coefficient = 0.91, Confidence interval: 0.84-0.95). Standard error of measurement was 2.9 and minimal detectable change was 8 points. (i.e., 11%). Good structural, convergent and divergent validity of the Dexterity questionnaire 24 was found (r = 0.73 with Activities of Daily Living-subscale of the Parkinson's Disease Questionnaire-39, and r = 0.66, and r = 0.50, p-values all < 0.0001, respectively with the subscales II and III of the Movement Disorders Society-Unified Parkinson Disease Rating Scale). Low not significant correlations were found between the Dexterity Questionnaire 24 and the subscales stigma and social support (r = 0.20, and r = 0.14 respectively). No floor or ceiling effects were found for the total Dexterity Questionnaire 24.CONCLUSION: The Dexterity Questionnaire 24 is valid and reliable for evaluating dexterity in patients with Parkinson's disease.
KW - Dexterity
KW - Parkinson's disease
KW - Patient reported questionnaire
KW - Reliability
KW - Validity
UR - http://www.scopus.com/inward/record.url?scp=84994691395&partnerID=8YFLogxK
U2 - 10.1016/j.parkreldis.2016.09.015
DO - 10.1016/j.parkreldis.2016.09.015
M3 - Article
C2 - 27663063
AN - SCOPUS:84994691395
VL - 33
SP - 78
EP - 83
JO - Parkinsonism and Related Disorders
JF - Parkinsonism and Related Disorders
SN - 1353-8020
ER -