Reliability of the mixing ability test testing masticatory performance in patients with head and neck cancer and healthy controls

Jorine A. Vermaire, Florine M. Weinberg, Cornelis P.J. Raaijmakers, Irma M. Verdonck-de Leeuw, Chris H.J. Terhaard, Caroline M. Speksnijder*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review


Background: Treatment of patients with head and neck cancer can result in disrupted mastication. To measure masticatory performance in people with compromised mastication, the mixing ability test (MAT) was developed. Objective: In this study, the reliability of the MAT was evaluated in patients with head and neck cancer and healthy controls. Methods: Thirty-four patients with head and neck cancer and 42 healthy controls performed the MAT twice on the same day. To assess reliability, the intra-class correlation coefficient (ICC2,1), standard error of measurement (SEM), smallest detectable change (SDC) and limits of agreement (LoA) were calculated. Results: A good (ICC = 0.886) and moderate correlation (ICC = 0.525) were found for patients and healthy controls, respectively. Patients had a worse mixing ability (mean = 19.12, SD = 4.56) in comparison with healthy controls (mean = 16.42, SD = 2.04). The SEM was 0.76 in patients and 1.45 in healthy controls, with a SDC of 2.12 and 4.02, respectively. The LoA was −4.46 to 4.42 in patients and −3.65 to 4.59 in healthy controls. Conclusion: The MAT has a good reliability in patients with head and neck cancer and a moderate reliability in healthy controls.

Original languageEnglish
Pages (from-to)961-966
Number of pages6
JournalJournal of Oral Rehabilitation
Issue number8
Publication statusPublished - 1 Aug 2020

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