Research Gaps in Diet and Nutrition in Inflammatory Bowel Disease. A Topical Review by D-ECCO Working Group [Dietitians of ECCO]

Rotem Sigall-Boneh, Arie Levine, Miranda Lomer, Nicolette Wierdsma, Philip Allan, Gionata Fiorino, Simona Gatti, Daisy Jonkers, Jaroslaw Kierkus, Konstantinos H Katsanos, Silvia Melgar, Elif Saritas Yuksel, Kevin Whelan, Eytan Wine, Konstantinos Gerasimidis

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Although the current doctrine of IBD pathogenesis proposes an interaction between environmental factors and gut microbiota in genetically susceptible individuals, dietary exposures have attracted recent interest and are, at least in part, likely to explain the rapid rise in disease incidence and prevalence. The D-ECCO working group along with other ECCO experts with expertise in nutrition, microbiology, physiology, and medicine reviewed the evidence investigating the role of diet and nutritional therapy in the onset, perpetuation, and management of IBD. A narrative topical review is presented where evidence pertinent to the topic is summarised collectively under three main thematic domains: i] the role of diet as an environmental factor in IBD aetiology; ii] the role of diet as induction and maintenance therapy in IBD; and iii] assessment of nutritional status and supportive nutritional therapy in IBD. A summary of research gaps for each of these thematic domains is proposed, which is anticipated to be agenda-setting for future research in the area of diet and nutrition in IBD.

Original languageEnglish
Pages (from-to)1407-1419
Number of pages13
JournalJournal of Crohn's & colitis
Volume11
Issue number12
DOIs
Publication statusPublished - 4 Dec 2017

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