Aangepast preventiebeleid bij patiënten met hyposplenie of asplenie

Translated title of the contribution: Revised prevention strategies for persons with (functional) hypo- or asplenie

Imke Schreuder, Frank P Kroon, Edgar J G Peters, Elisabeth A M Sanders, Joanne G Wildenbeest, Jolanda A J Lammers

Research output: Contribution to journalArticleProfessional

Abstract

The Dutch guideline for the preventions of infections in persons with (functional) hypo- or asplenie has been revised, recommending adjustments for the use of vaccinations and antibiotics. The spleen has an important function in the defence against infections. Around 1,000 splenectomies are performed in the Netherlands every year. Three different groups of patients are distinguished: (a) persons with a partially or completely removed spleen after surgery or embolization; (b) persons with congenital asplenia; and (c) a heterogeneous group of patients, who may have functional hyposplenie or asplenia due to an underlying condition or specific treatments. Patients with asplenia have an increased risk of severe infections by encapsulated bacteria, including in particular Streptococcus pneumoniae, but also Haemophilus influenzae type b and Neisseria meningitides may lead to an increased risk S.pneumoniae causes up to 90% of the infections, which makes it the most important infectious agent in patients with asplenia. A number of preventive measures are recommended to prevent infections in patients with hypo- or asplenie, including the use of vaccinations and antibiotics and patient counselling.

Original languageDutch
JournalNederlands Tijdschrift voor Geneeskunde
Volume163
Publication statusPublished - 4 Apr 2019

Cite this

Schreuder, I., Kroon, F. P., Peters, E. J. G., Sanders, E. A. M., Wildenbeest, J. G., & Lammers, J. A. J. (2019). Aangepast preventiebeleid bij patiënten met hyposplenie of asplenie. Nederlands Tijdschrift voor Geneeskunde, 163.