RF Heating of Pancreatic Tumours Guided by Hyperthermia Treatment Planning and Limited Thermometry

H. P. Kok, R. de Kroon-Oldenhof, L. Korshuize van Straten, C. E. de Jong, A. Bakker, R. Zweije, J. Sijbrands, G. van Tienhoven, J. Crezee

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

Abstract

Hyperthermia (i.e. heating tumour tissue to 39-43°C) is an oncological treatment to enhance the effect of radiotherapy and chemotherapy. RF heating of deep-seated tumours is performed using phased array systems. Antenna settings are usually determined based on clinical experience, assisted by E-field and temperature measurements in natural body cavities (e.g. cervix, bladder, rectum) adjacent to the tumour. When the tumour is not in the direct vicinity of a natural body cavity, e.g. pancreatic tumours, these probes cannot be positioned easily and adequate thermometry is very limited. Treatment planning can be helpful in addition to the limited thermometry available. The usefulness of treatment guidance by hyperthermia treatment planning and limited thermometry was evaluated for RF heating of two pancreatic cancer patients. Median temperatures measured in the duodenum were above 40°C for patient 1 and above 39°C for patient 2. This demonstrates that treatment planning is helpful to determine antenna settings for adequate hyperthermia treatments with limited thermometry.
Original languageEnglish
Title of host publication2018 48th European Microwave Conference, EuMC 2018
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages332-335
ISBN (Electronic)9782874870514
DOIs
Publication statusPublished - 2018
Externally publishedYes
Event48th European Microwave Conference, EuMC 2018 - Madrid, Spain
Duration: 25 Sep 201827 Sep 2018

Publication series

Name2018 48th European Microwave Conference, EuMC 2018

Conference

Conference48th European Microwave Conference, EuMC 2018
CountrySpain
CityMadrid
Period25/09/201827/09/2018

Cite this

Kok, H. P., de Kroon-Oldenhof, R., van Straten, L. K., de Jong, C. E., Bakker, A., Zweije, R., ... Crezee, J. (2018). RF Heating of Pancreatic Tumours Guided by Hyperthermia Treatment Planning and Limited Thermometry. In 2018 48th European Microwave Conference, EuMC 2018 (pp. 332-335). (2018 48th European Microwave Conference, EuMC 2018). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.23919/EuMC.2018.8541606