Risk factors for chronic inflammatory demyelinating polyradiculoneuropathy (CIDP): antecedent events, lifestyle and dietary habits. Data from the Italian CIDP Database

P. E. Doneddu, E. Bianchi, D. Cocito, F. Manganelli, R. Fazio, M. Filosto, A. Mazzeo, G. Cosentino, A. Cortese, S. Jann, A. M. Clerici, G. Antonini, G. Siciliano, M. Luigetti, G. A. Marfia, C. Briani, G. Lauria, T. Rosso, G. Cavaletti, M. Carpo & 17 others L. Benedetti, E. Beghi, G. Liberatore, L. Santoro, E. Peci, S. Tronci, S. C. Piccinelli, A. Toscano, L. Piccolo, E. P. Verrengia, L. Leonardi, E. Schirinzi, G. Mataluni, M. Ruiz, P. Dacci, E. Nobile-Orazio, the Italian CIDP Database Study Group

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Background and purpose: The role of lifestyle and dietary habits and antecedent events has not been clearly identified in chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). Methods: Information was collected about modifiable environmental factors and antecedent infections and vaccinations in patients with CIDP included in an Italian CIDP Database. Only patients who reported not having changed their diet or the lifestyle habits investigated in the study after the appearance of CIDP were included. The partners of patients with CIDP were chosen as controls. Gender-matched analysis was performed with randomly selected controls with a 1:1 ratio of patients and controls. Results: Dietary and lifestyle data of 323 patients and 266 controls were available. A total of 195 cases and 195 sex-matched controls were used in the analysis. Patients eating rice at least three times per week or eating fish at least once per week appeared to be at decreased risk of acquiring CIDP. Data on antecedent events were collected in 411 patients. Antecedent events within 1–42 days before CIDP onset were reported by 15.5% of the patients, including infections in 12% and vaccinations in 1.5%. Patients with CIDP and antecedent infections more often had an acute onset of CIDP and cranial nerve involvement than those without these antecedent events. Conclusions: The results of this preliminary study seem to indicate that some dietary habits may influence the risk of CIDP and that antecedent infections may have an impact on the onset and clinical presentation of the disease.
Original languageEnglish
JournalEuropean Journal of Neurology
Volume27
DOIs
Publication statusPublished - 1 Jan 2020
Externally publishedYes

Cite this

Doneddu, P. E. ; Bianchi, E. ; Cocito, D. ; Manganelli, F. ; Fazio, R. ; Filosto, M. ; Mazzeo, A. ; Cosentino, G. ; Cortese, A. ; Jann, S. ; Clerici, A. M. ; Antonini, G. ; Siciliano, G. ; Luigetti, M. ; Marfia, G. A. ; Briani, C. ; Lauria, G. ; Rosso, T. ; Cavaletti, G. ; Carpo, M. ; Benedetti, L. ; Beghi, E. ; Liberatore, G. ; Santoro, L. ; Peci, E. ; Tronci, S. ; Piccinelli, S. C. ; Toscano, A. ; Piccolo, L. ; Verrengia, E. P. ; Leonardi, L. ; Schirinzi, E. ; Mataluni, G. ; Ruiz, M. ; Dacci, P. ; Nobile-Orazio, E. ; the Italian CIDP Database Study Group. / Risk factors for chronic inflammatory demyelinating polyradiculoneuropathy (CIDP): antecedent events, lifestyle and dietary habits. Data from the Italian CIDP Database. In: European Journal of Neurology. 2020 ; Vol. 27.
@article{3fd264e1fa14432a9517db931a58b051,
title = "Risk factors for chronic inflammatory demyelinating polyradiculoneuropathy (CIDP): antecedent events, lifestyle and dietary habits. Data from the Italian CIDP Database",
abstract = "Background and purpose: The role of lifestyle and dietary habits and antecedent events has not been clearly identified in chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). Methods: Information was collected about modifiable environmental factors and antecedent infections and vaccinations in patients with CIDP included in an Italian CIDP Database. Only patients who reported not having changed their diet or the lifestyle habits investigated in the study after the appearance of CIDP were included. The partners of patients with CIDP were chosen as controls. Gender-matched analysis was performed with randomly selected controls with a 1:1 ratio of patients and controls. Results: Dietary and lifestyle data of 323 patients and 266 controls were available. A total of 195 cases and 195 sex-matched controls were used in the analysis. Patients eating rice at least three times per week or eating fish at least once per week appeared to be at decreased risk of acquiring CIDP. Data on antecedent events were collected in 411 patients. Antecedent events within 1–42 days before CIDP onset were reported by 15.5{\%} of the patients, including infections in 12{\%} and vaccinations in 1.5{\%}. Patients with CIDP and antecedent infections more often had an acute onset of CIDP and cranial nerve involvement than those without these antecedent events. Conclusions: The results of this preliminary study seem to indicate that some dietary habits may influence the risk of CIDP and that antecedent infections may have an impact on the onset and clinical presentation of the disease.",
author = "Doneddu, {P. E.} and E. Bianchi and D. Cocito and F. Manganelli and R. Fazio and M. Filosto and A. Mazzeo and G. Cosentino and A. Cortese and S. Jann and Clerici, {A. M.} and G. Antonini and G. Siciliano and M. Luigetti and Marfia, {G. A.} and C. Briani and G. Lauria and T. Rosso and G. Cavaletti and M. Carpo and L. Benedetti and E. Beghi and G. Liberatore and L. Santoro and E. Peci and S. Tronci and Piccinelli, {S. C.} and A. Toscano and L. Piccolo and Verrengia, {E. P.} and L. Leonardi and E. Schirinzi and G. Mataluni and M. Ruiz and P. Dacci and E. Nobile-Orazio and {the Italian CIDP Database Study Group}",
year = "2020",
month = "1",
day = "1",
doi = "10.1111/ene.14044",
language = "English",
volume = "27",
journal = "European Journal of Neurology",
issn = "1351-5101",
publisher = "Wiley-Blackwell",

}

Doneddu, PE, Bianchi, E, Cocito, D, Manganelli, F, Fazio, R, Filosto, M, Mazzeo, A, Cosentino, G, Cortese, A, Jann, S, Clerici, AM, Antonini, G, Siciliano, G, Luigetti, M, Marfia, GA, Briani, C, Lauria, G, Rosso, T, Cavaletti, G, Carpo, M, Benedetti, L, Beghi, E, Liberatore, G, Santoro, L, Peci, E, Tronci, S, Piccinelli, SC, Toscano, A, Piccolo, L, Verrengia, EP, Leonardi, L, Schirinzi, E, Mataluni, G, Ruiz, M, Dacci, P, Nobile-Orazio, E & the Italian CIDP Database Study Group 2020, 'Risk factors for chronic inflammatory demyelinating polyradiculoneuropathy (CIDP): antecedent events, lifestyle and dietary habits. Data from the Italian CIDP Database' European Journal of Neurology, vol. 27. https://doi.org/10.1111/ene.14044

Risk factors for chronic inflammatory demyelinating polyradiculoneuropathy (CIDP): antecedent events, lifestyle and dietary habits. Data from the Italian CIDP Database. / Doneddu, P. E.; Bianchi, E.; Cocito, D.; Manganelli, F.; Fazio, R.; Filosto, M.; Mazzeo, A.; Cosentino, G.; Cortese, A.; Jann, S.; Clerici, A. M.; Antonini, G.; Siciliano, G.; Luigetti, M.; Marfia, G. A.; Briani, C.; Lauria, G.; Rosso, T.; Cavaletti, G.; Carpo, M.; Benedetti, L.; Beghi, E.; Liberatore, G.; Santoro, L.; Peci, E.; Tronci, S.; Piccinelli, S. C.; Toscano, A.; Piccolo, L.; Verrengia, E. P.; Leonardi, L.; Schirinzi, E.; Mataluni, G.; Ruiz, M.; Dacci, P.; Nobile-Orazio, E.; the Italian CIDP Database Study Group.

In: European Journal of Neurology, Vol. 27, 01.01.2020.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - Risk factors for chronic inflammatory demyelinating polyradiculoneuropathy (CIDP): antecedent events, lifestyle and dietary habits. Data from the Italian CIDP Database

AU - Doneddu, P. E.

AU - Bianchi, E.

AU - Cocito, D.

AU - Manganelli, F.

AU - Fazio, R.

AU - Filosto, M.

AU - Mazzeo, A.

AU - Cosentino, G.

AU - Cortese, A.

AU - Jann, S.

AU - Clerici, A. M.

AU - Antonini, G.

AU - Siciliano, G.

AU - Luigetti, M.

AU - Marfia, G. A.

AU - Briani, C.

AU - Lauria, G.

AU - Rosso, T.

AU - Cavaletti, G.

AU - Carpo, M.

AU - Benedetti, L.

AU - Beghi, E.

AU - Liberatore, G.

AU - Santoro, L.

AU - Peci, E.

AU - Tronci, S.

AU - Piccinelli, S. C.

AU - Toscano, A.

AU - Piccolo, L.

AU - Verrengia, E. P.

AU - Leonardi, L.

AU - Schirinzi, E.

AU - Mataluni, G.

AU - Ruiz, M.

AU - Dacci, P.

AU - Nobile-Orazio, E.

AU - the Italian CIDP Database Study Group

PY - 2020/1/1

Y1 - 2020/1/1

N2 - Background and purpose: The role of lifestyle and dietary habits and antecedent events has not been clearly identified in chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). Methods: Information was collected about modifiable environmental factors and antecedent infections and vaccinations in patients with CIDP included in an Italian CIDP Database. Only patients who reported not having changed their diet or the lifestyle habits investigated in the study after the appearance of CIDP were included. The partners of patients with CIDP were chosen as controls. Gender-matched analysis was performed with randomly selected controls with a 1:1 ratio of patients and controls. Results: Dietary and lifestyle data of 323 patients and 266 controls were available. A total of 195 cases and 195 sex-matched controls were used in the analysis. Patients eating rice at least three times per week or eating fish at least once per week appeared to be at decreased risk of acquiring CIDP. Data on antecedent events were collected in 411 patients. Antecedent events within 1–42 days before CIDP onset were reported by 15.5% of the patients, including infections in 12% and vaccinations in 1.5%. Patients with CIDP and antecedent infections more often had an acute onset of CIDP and cranial nerve involvement than those without these antecedent events. Conclusions: The results of this preliminary study seem to indicate that some dietary habits may influence the risk of CIDP and that antecedent infections may have an impact on the onset and clinical presentation of the disease.

AB - Background and purpose: The role of lifestyle and dietary habits and antecedent events has not been clearly identified in chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). Methods: Information was collected about modifiable environmental factors and antecedent infections and vaccinations in patients with CIDP included in an Italian CIDP Database. Only patients who reported not having changed their diet or the lifestyle habits investigated in the study after the appearance of CIDP were included. The partners of patients with CIDP were chosen as controls. Gender-matched analysis was performed with randomly selected controls with a 1:1 ratio of patients and controls. Results: Dietary and lifestyle data of 323 patients and 266 controls were available. A total of 195 cases and 195 sex-matched controls were used in the analysis. Patients eating rice at least three times per week or eating fish at least once per week appeared to be at decreased risk of acquiring CIDP. Data on antecedent events were collected in 411 patients. Antecedent events within 1–42 days before CIDP onset were reported by 15.5% of the patients, including infections in 12% and vaccinations in 1.5%. Patients with CIDP and antecedent infections more often had an acute onset of CIDP and cranial nerve involvement than those without these antecedent events. Conclusions: The results of this preliminary study seem to indicate that some dietary habits may influence the risk of CIDP and that antecedent infections may have an impact on the onset and clinical presentation of the disease.

UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85070298192&origin=inward

UR - https://www.ncbi.nlm.nih.gov/pubmed/31325350

U2 - 10.1111/ene.14044

DO - 10.1111/ene.14044

M3 - Article

VL - 27

JO - European Journal of Neurology

JF - European Journal of Neurology

SN - 1351-5101

ER -