Safety and efficacy of losartan for the reduction of brain atrophy in clinically diagnosed Alzheimer's disease (the RADAR trial): a double-blind, randomised, placebo-controlled, phase 2 trial

Patrick Gavin Kehoe; Nicholas Turner; Beth Howden; Lina Jarutyte; Shona Louise Clegg; Ian Brian Malone; Josephine Barnes; Casper Nielsen; Carole Helene Sudre; Aileen Wilson; Ngoc Jade Thai; Peter Sinclair Blair; Elizabeth Coulthard; Janet Athene Lane; Peter Passmore; Jodi Taylor; Henk-Jan Mutsaerts; David Lee Thomas; Nick Charles Fox; Ian Wilkinson; Yoav Ben-Shlomo

Safety and efficacy of losartan for the reduction of brain atrophy in clinically diagnosed Alzheimer's disease (the RADAR trial): a double-blind, randomised, placebo-controlled, phase 2 trial

Patrick Gavin Kehoe, Nicholas Turner, Beth Howden, Lina Jarutyte, Shona Louise Clegg, Ian Brian Malone, Josephine Barnes, Casper Nielsen, Carole Helene Sudre, Aileen Wilson, Ngoc Jade Thai, Peter Sinclair Blair, Elizabeth Coulthard, Janet Athene Lane, Peter Passmore, Jodi Taylor, Henk-Jan Mutsaerts, David Lee Thomas, Nick Charles Fox, Ian WilkinsonYoav Ben-Shlomo

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	895-906
Journal	Lancet Neurology
Volume	20
Issue number	11
Publication status	Published - Nov 2021

Cite this

Kehoe, P. G., Turner, N., Howden, B., Jarutyte, L., Clegg, S. L., Malone, I. B., Barnes, J., Nielsen, C., Sudre, C. H., Wilson, A., Thai, N. J., Blair, P. S., Coulthard, E., Lane, J. A., Passmore, P., Taylor, J., Mutsaerts, H-J., Thomas, D. L., Fox, N. C., ... Ben-Shlomo, Y. (2021). Safety and efficacy of losartan for the reduction of brain atrophy in clinically diagnosed Alzheimer's disease (the RADAR trial): a double-blind, randomised, placebo-controlled, phase 2 trial. Lancet Neurology, 20(11), 895-906.

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title = "Safety and efficacy of losartan for the reduction of brain atrophy in clinically diagnosed Alzheimer's disease (the RADAR trial): a double-blind, randomised, placebo-controlled, phase 2 trial",

author = "Kehoe, {Patrick Gavin} and Nicholas Turner and Beth Howden and Lina Jarutyte and Clegg, {Shona Louise} and Malone, {Ian Brian} and Josephine Barnes and Casper Nielsen and Sudre, {Carole Helene} and Aileen Wilson and Thai, {Ngoc Jade} and Blair, {Peter Sinclair} and Elizabeth Coulthard and Lane, {Janet Athene} and Peter Passmore and Jodi Taylor and Henk-Jan Mutsaerts and Thomas, {David Lee} and Fox, {Nick Charles} and Ian Wilkinson and Yoav Ben-Shlomo",

year = "2021",

month = nov,

language = "English",

volume = "20",

pages = "895--906",

journal = "Lancet Neurology",

issn = "1474-4422",

publisher = "Lancet Publishing Group",

number = "11",

}

Kehoe, PG, Turner, N, Howden, B, Jarutyte, L, Clegg, SL, Malone, IB, Barnes, J, Nielsen, C, Sudre, CH, Wilson, A, Thai, NJ, Blair, PS, Coulthard, E, Lane, JA, Passmore, P, Taylor, J, Mutsaerts, H-J, Thomas, DL, Fox, NC, Wilkinson, I & Ben-Shlomo, Y 2021, 'Safety and efficacy of losartan for the reduction of brain atrophy in clinically diagnosed Alzheimer's disease (the RADAR trial): a double-blind, randomised, placebo-controlled, phase 2 trial', Lancet Neurology, vol. 20, no. 11, pp. 895-906.

Safety and efficacy of losartan for the reduction of brain atrophy in clinically diagnosed Alzheimer's disease (the RADAR trial): a double-blind, randomised, placebo-controlled, phase 2 trial. / Kehoe, Patrick Gavin; Turner, Nicholas; Howden, Beth et al.

In: Lancet Neurology, Vol. 20, No. 11, 11.2021, p. 895-906.

Research output: Contribution to journal › Article › Academic › peer-review

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T1 - Safety and efficacy of losartan for the reduction of brain atrophy in clinically diagnosed Alzheimer's disease (the RADAR trial): a double-blind, randomised, placebo-controlled, phase 2 trial

AU - Kehoe, Patrick Gavin

AU - Turner, Nicholas

AU - Howden, Beth

AU - Jarutyte, Lina

AU - Clegg, Shona Louise

AU - Malone, Ian Brian

AU - Barnes, Josephine

AU - Nielsen, Casper

AU - Sudre, Carole Helene

AU - Wilson, Aileen

AU - Thai, Ngoc Jade

AU - Blair, Peter Sinclair

AU - Coulthard, Elizabeth

AU - Lane, Janet Athene

AU - Passmore, Peter

AU - Taylor, Jodi

AU - Mutsaerts, Henk-Jan

AU - Thomas, David Lee

AU - Fox, Nick Charles

AU - Wilkinson, Ian

AU - Ben-Shlomo, Yoav

PY - 2021/11

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M3 - Article

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VL - 20

SP - 895

EP - 906

JO - Lancet Neurology

JF - Lancet Neurology

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