Abstract
Right ventricular (RV) volume
measurements with cardiovascular
magnetic resonance (CMR) is
considered the gold standard, but
acquisition and analysis remain timeconsuming.
The aim of our study was
therefore to investigate the accuracy
and performance of a semi-quantitative
assessment of RV function in
CMR, compared to the standard
quantitative approach. Seventy-five
subjects with pulmonary hypertension
(15), anterior myocardial infarction
(15), inferior myocardial infarction
(15), Brugada syndrome (15)
and normal subjects (15) underwent
cine CMR. RV end-systolic and enddiastolic
volumes were determined to
calculate RV ejection fraction (EF).
Four-chamber cine images were used
to measure tricuspid annular plane
systolic excursion (TAPSE). RV fractional
shortening (RVFS) was calculated
by dividing TAPSE by the RV
end-diastolic length. RV EF correlated
significantly with TAPSE (r = 0.62,
p < 0.01) and RVFS (r = 0.67, p < 0.01).
Sensitivity to predict RV dysfunction
was comparable between TAPSE and
RVFS, with higher specificity for
RVFS, but comparable areas under the
ROC curve. Intra- and inter-observer
variability of RV EF was better than
TAPSE (3%/4% versus 7%/15%,
respectively). For routine screening in
clinical practice, TAPSE and RVFS
seem reliable and easy methods to
identify patients with RV dysfunction.
The 3D volumetric approach is preferred
to assess RV function for
research purposes or to evaluate
treatment response.
Original language | English |
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Journal | European Radiology |
Publication status | Published - 2008 |