TY - JOUR
T1 - Severe complications of perianal sepsis in patients with human immunodeficiency virus
AU - Consten, E. C.J.
AU - Slors, J. F.M.
AU - Danner, S. A.
AU - Sars, P. R.A.
AU - Obertop, H.
AU - Van Lanschot, J. J.B.
PY - 1996
Y1 - 1996
N2 - Fifty human immunodeficiency virus (HIV)-infected patients with perianal sepsis were studied. Seven (14 per cent) had serious septic complications, four patients with severe necrotizing gangrene, and three with abscesses in the mediastinum, liver and brain respectively. CD4+ lymphocyte counts were significantly lower in patients with severe septic complications as compared with those with uncomplicated perianal sepsis (P < 0.05). In patients with HIV presenting with rare (metastatic) abscesses, perianal sepsis must always be kept in mind as a possible focus. Although HIV-infected patients have a limited life expectancy perianal fistulas and abscesses should be aggressively treated, because of the high risk of severe complications.
AB - Fifty human immunodeficiency virus (HIV)-infected patients with perianal sepsis were studied. Seven (14 per cent) had serious septic complications, four patients with severe necrotizing gangrene, and three with abscesses in the mediastinum, liver and brain respectively. CD4+ lymphocyte counts were significantly lower in patients with severe septic complications as compared with those with uncomplicated perianal sepsis (P < 0.05). In patients with HIV presenting with rare (metastatic) abscesses, perianal sepsis must always be kept in mind as a possible focus. Although HIV-infected patients have a limited life expectancy perianal fistulas and abscesses should be aggressively treated, because of the high risk of severe complications.
UR - http://www.scopus.com/inward/record.url?scp=0030029721&partnerID=8YFLogxK
U2 - 10.1002/bjs.1800830616
DO - 10.1002/bjs.1800830616
M3 - Article
C2 - 8696738
AN - SCOPUS:0030029721
VL - 83
SP - 778
EP - 780
JO - British Journal of Surgery
JF - British Journal of Surgery
SN - 0007-1323
IS - 6
ER -