Sex-stratified Genome-wide Association Studies Including 270000 Individuals Show Sexual Dimorphism in Genetic Loci for Anthropometric Traits

J.C. Randall, T.W. Winkler, Z. Kutalik, S.I. Berndt, A.U. Jackson, K.L. Monda, T.O. Kilpeläinen, T. Esko, R. Mägi, S. Li, T. Workalemahu, M.F. Feitosa, D.C. Croteau-Chonka, F.R. Day, T. Fall, T. Ferreira, S. Gustafsson, A.E. Locke, I. Mathieson, A. ScheragS. Vedantam, A.R. Wood, L. Liang, V. Steinthorsdottir, G. Thorleifsson, E.T. Dermitzakis, A.S. Dimas, F. Karpe, J.L. Min, G. Nicholson, D.J. Clegg, T. Person, J.P. Krohn, S. Bauer, C. Buechler, K. Eisinger, A. Bonnefond, P. Froguel, J.J. Hottenga, I. Prokopenko, L.L. Waite, T.B. Harris, A.V. Smith, A.R. Shuldiner, W.L. McArdle, M.J. Caulfield, P.B. Munroe, H. Grönberg, Y.D. Chen, G. Li, J.S. Beckmann, T. Johnson, U. Thorsteinsdottir, M. Teder-Laving, K.T. Khaw, N.J. Wareham, J.H. Zhao, N. Amin, B.A. Oostra, A.T. Kraja, M.A. Province, L.A. Cupples, N.L. Heard-Costa, J. Kaprio, S. Ripatti, I. Surakka, F.S. Collins, J. Saramies, J. Tuomilehto, A. Jula, V. Salomaa, J. Erdmann, C. Hengstenberg, C. Loley, H. Schunkert, C. Lamina, H.E. Wichmann, E. Albrecht, C. Gieger, A.A. Hicks, A. Johansson, P.P. Pramstaller, S. Kathiresan, E.K. Speliotes, B.W.J.H. Penninx, A.L. Hartikainen, M.R. Järvelin, U. Gyllensten, D.I. Boomsma, H. Campbell, J.F. Wilson, S.J. Chanock, M. Farrall, A. Goel, C. Medina-Gomez, F. Rivadeneira, K. Estrada, A.G. Uitterlinden, A. Hofman, M.C. Zillikens, M. den Heijer, L.A. Kiemeney, A. Maschio, P. Hall, J. Tyrer, A. Teumer, H. Völzke, P. Kovacs, A. Tönjes, M. Mangino, T.D. Spector, C. Hayward, I. Rudan, A.S. Hall, N.J. Samani, A.P. Attwood, J.G. Sambrook, J. Hung, L.J. Palmer, M.L. Lokki, J. Sinisalo, G. Boucher, H.V. Huikuri, M. Lorentzon, C. Ohlsson, N. Eklund, J.G. Eriksson, C. Barlassina, C. Rivolta, I.M. Nolte, H. Snieder, M.M. van der Klauw, J.V. van Vliet-Ostaptchouk, P.V. Gejman, J. Shi, K.B. Jacobs, Z. Wang, S.J. Bakker, I. Mateo Leach, G. Navis, P. van der Harst, N.G. Martin, S.E. Medland, G.W. Montgomery, J. Yang, D.I. Chasman, P.M. Ridker, L.M. Rose, T. Lehtimäki, O. Raitakari, D. Absher, C. Iribarren, H. Basart, K.G. Hovingh, E. Hyppönen, C. Power, D. Anderson, J.P. Beilby, J. Hui, J. Jolley, H. Sager, S.R. Bornstein, P.E. Schwarz, K. Kristiansson, M. Perola, J. Lindström, A.J. Swift, M. Uusitupa, M. Atalay, T.A. Lakka, R. Rauramaa, J.L. Bolton, G. Fowkes, R.M. Fraser, J.F. Price, K. Fischer, K. Krjuta Kov, A. Metspalu, E. Mihailov, C. Langenberg, J. Luan, K.K. Ong, P.S. Chines, S. Keinanen-Kiukaanniemie, T.E. Saaristo, S. Edkins, P.W. Franks, G. Hallmans, D. Shungin, A.D. Morris, C.N.A. Palmer, R. Erbel, S. Moebus, M.M. Nöthen, S. Pechlivanis, K. Hveem, N. Narisu, A. Hamsten, S.E. Humphries, R.J. Strawbridge, E. Tremoli, H. Grallert, B. Thorand, T. Illig, W. Koenig, M. Müller-Nurasyid, A. Peters, B.O. Boehm, M.E. Kleber, W. März, B.R. Winkelmann, J. Kuusisto, M. Laakso, D. Arveiler, G. Cesana, K. Kuulasmaa, J. Virtamo, J.W. Yarnell, D Kuh, A. Wong, L. Lind, U. de Faire, B. Gigante, P.K.E. Magnusson, N.L. Pedersen, G. Dedoussis, M. Dimitriou, G. Kolovou, S. Kanoni, K. Stirrups, L.L. Bonnycastle, I. Njolstad, T. Wilsgaard, A. Ganna, E. Rehnberg, A.D. Hingorani, M. Kivimaki, M. Kumari, T.L. Assimes, I. Barroso, M. Boehnke, I.B. Borecki, P. Deloukas, C.S. Fox, T.M. Frayling, L.C. Groop, T. Haritunians, D. Hunter, E. Ingelsson, R. Kaplan, K.L. Mohlke, J.R. O'Connell, D. Schlessinger, D.P. Strachan, K. Stefansson, C.M. van Duijn, G.R. Abecasis, M.I. McCarthy, J.N. Hirschhorn, L. Qi, R.J. Loos, C.M. Lindgren, K.E. North, I.M. Heid

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Article numbere1003500
Pages (from-to)e1003500
JournalPLoS Genetics
Volume9
Issue number6
DOIs
Publication statusPublished - 2013

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Randall, J. C., Winkler, T. W., Kutalik, Z., Berndt, S. I., Jackson, A. U., Monda, K. L., ... Heid, I. M. (2013). Sex-stratified Genome-wide Association Studies Including 270000 Individuals Show Sexual Dimorphism in Genetic Loci for Anthropometric Traits. PLoS Genetics, 9(6), e1003500. [e1003500]. https://doi.org/10.1371/journal.pgen.1003500