Short-term patterns of pulsatile luteinizing hormone secretion do not differ between male-to-female transsexuals and heterosexual men

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

This study tested whether there is a difference in the pulsatile LH secretion between male-to-female transsexuals and eugonadal heterosexual men. The mean serum LH concentrations, the LH pulse frequency, and the LH pulse amplitude were compared between a group of eight male-to-female transsexuals and a group of 22 heterosexual men. Blood samples for LH determinations were collected every 10 min for seven hours. 17-β-estradiol and testosterone were measured at the beginning of each test. There were no significant differences between the heterosexual and transsexual group in LH pulse frequency (3.9±1.3 vs. 3.9±1.7), LH pulse amplitude (3.7±1.3 U/l vs. 3.0±0.5 U/l), mean serum LH concentration (5.2±1.4 U/l vs. 5.4±1.1 U/l), 17-β-estradiol (0.07±0.01 nmol/l vs. 0.08±0.02 nmol/l), or testosterone (22.9±3.7 nmol/l vs. 21.8±8.0 nmol/l). We conclude that the pulsatile release characteristics of LH do not allow a distinction between eugonadal heterosexual men and eugonadal male-to-female transsexuals.

Original languageEnglish
Pages (from-to)279-283
Number of pages5
JournalPsychoneuroendocrinology
Volume13
Issue number3
DOIs
Publication statusPublished - 1 Jan 1988

Cite this

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title = "Short-term patterns of pulsatile luteinizing hormone secretion do not differ between male-to-female transsexuals and heterosexual men",
abstract = "This study tested whether there is a difference in the pulsatile LH secretion between male-to-female transsexuals and eugonadal heterosexual men. The mean serum LH concentrations, the LH pulse frequency, and the LH pulse amplitude were compared between a group of eight male-to-female transsexuals and a group of 22 heterosexual men. Blood samples for LH determinations were collected every 10 min for seven hours. 17-β-estradiol and testosterone were measured at the beginning of each test. There were no significant differences between the heterosexual and transsexual group in LH pulse frequency (3.9±1.3 vs. 3.9±1.7), LH pulse amplitude (3.7±1.3 U/l vs. 3.0±0.5 U/l), mean serum LH concentration (5.2±1.4 U/l vs. 5.4±1.1 U/l), 17-β-estradiol (0.07±0.01 nmol/l vs. 0.08±0.02 nmol/l), or testosterone (22.9±3.7 nmol/l vs. 21.8±8.0 nmol/l). We conclude that the pulsatile release characteristics of LH do not allow a distinction between eugonadal heterosexual men and eugonadal male-to-female transsexuals.",
author = "Spijkstra, {J. J.} and T. Spinder and Gooren, {L. J.G.}",
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Short-term patterns of pulsatile luteinizing hormone secretion do not differ between male-to-female transsexuals and heterosexual men. / Spijkstra, J. J.; Spinder, T.; Gooren, L. J.G.

In: Psychoneuroendocrinology, Vol. 13, No. 3, 01.01.1988, p. 279-283.

Research output: Contribution to journalArticleAcademicpeer-review

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