Small bowel obstruction, incisional hernia and survival after laparoscopic and open colonic resection (LAFA study)

S. A.L. Bartels, M. S. Vlug, M. W. Hollmann, M. G.W. Dijkgraaf, D. T. Ubbink, H. A. Cense, B. A. Van Wagensveld, A. F. Engel, M. F. Gerhards, W. A. Bemelman, LAFA Study Group

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Background Short-term advantages to laparoscopic surgery are well described. This study compared medium- to long-term outcomes of a randomized clinical trial comparing laparoscopic and open colonic resection for cancer. Methods The case notes of patients included in the LAFA study (perioperative strategy in colonic surgery; LAparoscopy and/or FAst track multimodal management versus standard care) were reviewed 2-5 years after randomization for incisional hernia, adhesional small bowel obstruction (SBO), overall survival, cancer recurrence and quality of life (QoL). The laparoscopic and open groups were compared irrespective of fast-track or standard perioperative care. Results Data on incisional hernias, SBO, survival and recurrence were available for 399 of 400 patients: 208 laparoscopic and 191 open resections. These outcomes were corrected for duration of follow-up. Median follow-up was 3·4 (i.q.r. 2·6-4·4) years. Multivariable regression analysis showed that open resection was a risk factor for incisional hernia (odds ratio (OR) 2·44, 95 per cent confidence interval (c.i.) 1·12 to 5·26; P = 0·022) and SBO (OR 3·70, 1·07 to 12·50; P = 0·039). There were no differences in overall survival (hazard ratio 1·10, 95 per cent c.i. 0·67 to 1·80; P = 0·730) or in cumulative incidence of recurrence (P = 0·514) between the laparoscopic and open groups. There were no measured differences in QoL in 281 respondents (P > 0·350 for all scales). Conclusion Laparoscopic colonic surgery led to fewer incisional hernia and adhesional SBO events. Registration number: NTR222 (http://www.trialregister.nl). Another score for laparoscopic surgery

Original languageEnglish
Pages (from-to)1153-1159
Number of pages7
JournalBritish Journal of Surgery
Volume101
Issue number9
DOIs
Publication statusPublished - 2014

Cite this

Bartels, S. A. L., Vlug, M. S., Hollmann, M. W., Dijkgraaf, M. G. W., Ubbink, D. T., Cense, H. A., ... LAFA Study Group (2014). Small bowel obstruction, incisional hernia and survival after laparoscopic and open colonic resection (LAFA study). British Journal of Surgery, 101(9), 1153-1159. https://doi.org/10.1002/bjs.9585
Bartels, S. A.L. ; Vlug, M. S. ; Hollmann, M. W. ; Dijkgraaf, M. G.W. ; Ubbink, D. T. ; Cense, H. A. ; Van Wagensveld, B. A. ; Engel, A. F. ; Gerhards, M. F. ; Bemelman, W. A. ; LAFA Study Group. / Small bowel obstruction, incisional hernia and survival after laparoscopic and open colonic resection (LAFA study). In: British Journal of Surgery. 2014 ; Vol. 101, No. 9. pp. 1153-1159.
@article{dd6c2b4b7ab74c00a1674c88ebb90c22,
title = "Small bowel obstruction, incisional hernia and survival after laparoscopic and open colonic resection (LAFA study)",
abstract = "Background Short-term advantages to laparoscopic surgery are well described. This study compared medium- to long-term outcomes of a randomized clinical trial comparing laparoscopic and open colonic resection for cancer. Methods The case notes of patients included in the LAFA study (perioperative strategy in colonic surgery; LAparoscopy and/or FAst track multimodal management versus standard care) were reviewed 2-5 years after randomization for incisional hernia, adhesional small bowel obstruction (SBO), overall survival, cancer recurrence and quality of life (QoL). The laparoscopic and open groups were compared irrespective of fast-track or standard perioperative care. Results Data on incisional hernias, SBO, survival and recurrence were available for 399 of 400 patients: 208 laparoscopic and 191 open resections. These outcomes were corrected for duration of follow-up. Median follow-up was 3·4 (i.q.r. 2·6-4·4) years. Multivariable regression analysis showed that open resection was a risk factor for incisional hernia (odds ratio (OR) 2·44, 95 per cent confidence interval (c.i.) 1·12 to 5·26; P = 0·022) and SBO (OR 3·70, 1·07 to 12·50; P = 0·039). There were no differences in overall survival (hazard ratio 1·10, 95 per cent c.i. 0·67 to 1·80; P = 0·730) or in cumulative incidence of recurrence (P = 0·514) between the laparoscopic and open groups. There were no measured differences in QoL in 281 respondents (P > 0·350 for all scales). Conclusion Laparoscopic colonic surgery led to fewer incisional hernia and adhesional SBO events. Registration number: NTR222 (http://www.trialregister.nl). Another score for laparoscopic surgery",
author = "Bartels, {S. A.L.} and Vlug, {M. S.} and Hollmann, {M. W.} and Dijkgraaf, {M. G.W.} and Ubbink, {D. T.} and Cense, {H. A.} and {Van Wagensveld}, {B. A.} and Engel, {A. F.} and Gerhards, {M. F.} and Bemelman, {W. A.} and Cuesta, {M. A.} and {Van Geloven}, {A. A.W.} and {Van Der Zaag}, {E. S.} and J. Wind and B. Preckel and P. Bossuyt and D. Gouma and M. Sprangers and {Van Berge Henegouwen}, {M. I.} and Tanis, {P. J.} and Buskens, {C. J.} and {Picard Van Lenthe}, I. and C. Bakker and DeJong, {C. H.} and {van Dam}, {Ronald M.} and {Van Der Peet}, D. and {Van Zalingen}, E. and A. Noordhuis and Goei, {T. H.} and {Van Tets}, W. and L. DeWit and W. Clevers and A. Bieleman and L. Coenen and E. Bonekamp and {Van Abeelen}, J. and {Van Iterson-De Jong}, D. and M. Krombeen and {LAFA Study Group}",
year = "2014",
doi = "10.1002/bjs.9585",
language = "English",
volume = "101",
pages = "1153--1159",
journal = "British Journal of Surgery",
issn = "0007-1323",
publisher = "John Wiley and Sons Ltd",
number = "9",

}

Bartels, SAL, Vlug, MS, Hollmann, MW, Dijkgraaf, MGW, Ubbink, DT, Cense, HA, Van Wagensveld, BA, Engel, AF, Gerhards, MF, Bemelman, WA & LAFA Study Group 2014, 'Small bowel obstruction, incisional hernia and survival after laparoscopic and open colonic resection (LAFA study)' British Journal of Surgery, vol. 101, no. 9, pp. 1153-1159. https://doi.org/10.1002/bjs.9585

Small bowel obstruction, incisional hernia and survival after laparoscopic and open colonic resection (LAFA study). / Bartels, S. A.L.; Vlug, M. S.; Hollmann, M. W.; Dijkgraaf, M. G.W.; Ubbink, D. T.; Cense, H. A.; Van Wagensveld, B. A.; Engel, A. F.; Gerhards, M. F.; Bemelman, W. A.; LAFA Study Group.

In: British Journal of Surgery, Vol. 101, No. 9, 2014, p. 1153-1159.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - Small bowel obstruction, incisional hernia and survival after laparoscopic and open colonic resection (LAFA study)

AU - Bartels, S. A.L.

AU - Vlug, M. S.

AU - Hollmann, M. W.

AU - Dijkgraaf, M. G.W.

AU - Ubbink, D. T.

AU - Cense, H. A.

AU - Van Wagensveld, B. A.

AU - Engel, A. F.

AU - Gerhards, M. F.

AU - Bemelman, W. A.

AU - Cuesta, M. A.

AU - Van Geloven, A. A.W.

AU - Van Der Zaag, E. S.

AU - Wind, J.

AU - Preckel, B.

AU - Bossuyt, P.

AU - Gouma, D.

AU - Sprangers, M.

AU - Van Berge Henegouwen, M. I.

AU - Tanis, P. J.

AU - Buskens, C. J.

AU - Picard Van Lenthe, I.

AU - Bakker, C.

AU - DeJong, C. H.

AU - van Dam, Ronald M.

AU - Van Der Peet, D.

AU - Van Zalingen, E.

AU - Noordhuis, A.

AU - Goei, T. H.

AU - Van Tets, W.

AU - DeWit, L.

AU - Clevers, W.

AU - Bieleman, A.

AU - Coenen, L.

AU - Bonekamp, E.

AU - Van Abeelen, J.

AU - Van Iterson-De Jong, D.

AU - Krombeen, M.

AU - LAFA Study Group

PY - 2014

Y1 - 2014

N2 - Background Short-term advantages to laparoscopic surgery are well described. This study compared medium- to long-term outcomes of a randomized clinical trial comparing laparoscopic and open colonic resection for cancer. Methods The case notes of patients included in the LAFA study (perioperative strategy in colonic surgery; LAparoscopy and/or FAst track multimodal management versus standard care) were reviewed 2-5 years after randomization for incisional hernia, adhesional small bowel obstruction (SBO), overall survival, cancer recurrence and quality of life (QoL). The laparoscopic and open groups were compared irrespective of fast-track or standard perioperative care. Results Data on incisional hernias, SBO, survival and recurrence were available for 399 of 400 patients: 208 laparoscopic and 191 open resections. These outcomes were corrected for duration of follow-up. Median follow-up was 3·4 (i.q.r. 2·6-4·4) years. Multivariable regression analysis showed that open resection was a risk factor for incisional hernia (odds ratio (OR) 2·44, 95 per cent confidence interval (c.i.) 1·12 to 5·26; P = 0·022) and SBO (OR 3·70, 1·07 to 12·50; P = 0·039). There were no differences in overall survival (hazard ratio 1·10, 95 per cent c.i. 0·67 to 1·80; P = 0·730) or in cumulative incidence of recurrence (P = 0·514) between the laparoscopic and open groups. There were no measured differences in QoL in 281 respondents (P > 0·350 for all scales). Conclusion Laparoscopic colonic surgery led to fewer incisional hernia and adhesional SBO events. Registration number: NTR222 (http://www.trialregister.nl). Another score for laparoscopic surgery

AB - Background Short-term advantages to laparoscopic surgery are well described. This study compared medium- to long-term outcomes of a randomized clinical trial comparing laparoscopic and open colonic resection for cancer. Methods The case notes of patients included in the LAFA study (perioperative strategy in colonic surgery; LAparoscopy and/or FAst track multimodal management versus standard care) were reviewed 2-5 years after randomization for incisional hernia, adhesional small bowel obstruction (SBO), overall survival, cancer recurrence and quality of life (QoL). The laparoscopic and open groups were compared irrespective of fast-track or standard perioperative care. Results Data on incisional hernias, SBO, survival and recurrence were available for 399 of 400 patients: 208 laparoscopic and 191 open resections. These outcomes were corrected for duration of follow-up. Median follow-up was 3·4 (i.q.r. 2·6-4·4) years. Multivariable regression analysis showed that open resection was a risk factor for incisional hernia (odds ratio (OR) 2·44, 95 per cent confidence interval (c.i.) 1·12 to 5·26; P = 0·022) and SBO (OR 3·70, 1·07 to 12·50; P = 0·039). There were no differences in overall survival (hazard ratio 1·10, 95 per cent c.i. 0·67 to 1·80; P = 0·730) or in cumulative incidence of recurrence (P = 0·514) between the laparoscopic and open groups. There were no measured differences in QoL in 281 respondents (P > 0·350 for all scales). Conclusion Laparoscopic colonic surgery led to fewer incisional hernia and adhesional SBO events. Registration number: NTR222 (http://www.trialregister.nl). Another score for laparoscopic surgery

UR - http://www.scopus.com/inward/record.url?scp=84904578628&partnerID=8YFLogxK

U2 - 10.1002/bjs.9585

DO - 10.1002/bjs.9585

M3 - Article

VL - 101

SP - 1153

EP - 1159

JO - British Journal of Surgery

JF - British Journal of Surgery

SN - 0007-1323

IS - 9

ER -