Socially isolated individuals are more prone to have newly diagnosed and prevalent type 2 diabetes mellitus - The Maastricht study - The M

Stephanie Brinkhues, Nicole H.T.M. Dukers-Muijrers, Christian J.P.A. Hoebe, Carla J.H. Van Der Kallen, Pieter C. Dagnelie, Annemarie Koster, Ronald M.A. Henry, Simone J.S. Sep, Nicolaas C. Schaper, Coen D.A. Stehouwer, Hans Bosma, Paul H.M. Savelkoul, Miranda T. Schram

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Background: Social isolation is associated with type 2 diabetes (T2DM), but it is unclear which elements play a crucial role in this association. Therefore, we assessed the associations of a broad range of structural and functional social network characteristics with normal glucose metabolism, pre-diabetes, newly diagnosed T2DM and previously diagnosed T2DM. Methods: Participants originated from The Maastricht Study, a population-based cohort study (n = 2861, mean age 60.0 ± 8.2 years, 49% female, 28.8% T2DM (oversampled)). Social network characteristics were assessed through a name generator questionnaire. Diabetes status was determined by an oral glucose tolerance test. We used multinomial regression analyses to investigate the associations between social network characteristics and diabetes status, stratified by sex. Results: More socially isolated individuals (smaller social network size) more frequently had newly diagnosed and previously diagnosed T2DM, while this association was not observed with pre-diabetes. In women, proximity and the type of relationship was associated with newly diagnosed and previously diagnosed T2DM. A lack of social participation was associated with pre-diabetes as well as with previously diagnosed T2DM in women, and with previously diagnosed T2DM in men. Living alone was associated with higher odds of previously diagnosed T2DM in men, but not in women. Less emotional support related to important decisions, less practical support related to jobs, and less practical support for sickness were associated with newly diagnosed and previously diagnosed T2DM in men and women, but not in pre-diabetes. Conclusion: This study shows that several aspects of structural and functional characteristics of the social network were associated with newly and previously diagnosed T2DM, partially different for men and women. These results may provide useful targets for T2DM prevention efforts.

Original languageEnglish
Article number955
JournalBMC Public Health
Volume17
Issue number1
DOIs
Publication statusPublished - 19 Dec 2017

Cite this

Brinkhues, S., Dukers-Muijrers, N. H. T. M., Hoebe, C. J. P. A., Van Der Kallen, C. J. H., Dagnelie, P. C., Koster, A., ... Schram, M. T. (2017). Socially isolated individuals are more prone to have newly diagnosed and prevalent type 2 diabetes mellitus - The Maastricht study - The M. BMC Public Health, 17(1), [955]. https://doi.org/10.1186/s12889-017-4948-6
Brinkhues, Stephanie ; Dukers-Muijrers, Nicole H.T.M. ; Hoebe, Christian J.P.A. ; Van Der Kallen, Carla J.H. ; Dagnelie, Pieter C. ; Koster, Annemarie ; Henry, Ronald M.A. ; Sep, Simone J.S. ; Schaper, Nicolaas C. ; Stehouwer, Coen D.A. ; Bosma, Hans ; Savelkoul, Paul H.M. ; Schram, Miranda T. / Socially isolated individuals are more prone to have newly diagnosed and prevalent type 2 diabetes mellitus - The Maastricht study - The M. In: BMC Public Health. 2017 ; Vol. 17, No. 1.
@article{cea35302b0574e66b1a94927c4f5fbe9,
title = "Socially isolated individuals are more prone to have newly diagnosed and prevalent type 2 diabetes mellitus - The Maastricht study - The M",
abstract = "Background: Social isolation is associated with type 2 diabetes (T2DM), but it is unclear which elements play a crucial role in this association. Therefore, we assessed the associations of a broad range of structural and functional social network characteristics with normal glucose metabolism, pre-diabetes, newly diagnosed T2DM and previously diagnosed T2DM. Methods: Participants originated from The Maastricht Study, a population-based cohort study (n = 2861, mean age 60.0 ± 8.2 years, 49{\%} female, 28.8{\%} T2DM (oversampled)). Social network characteristics were assessed through a name generator questionnaire. Diabetes status was determined by an oral glucose tolerance test. We used multinomial regression analyses to investigate the associations between social network characteristics and diabetes status, stratified by sex. Results: More socially isolated individuals (smaller social network size) more frequently had newly diagnosed and previously diagnosed T2DM, while this association was not observed with pre-diabetes. In women, proximity and the type of relationship was associated with newly diagnosed and previously diagnosed T2DM. A lack of social participation was associated with pre-diabetes as well as with previously diagnosed T2DM in women, and with previously diagnosed T2DM in men. Living alone was associated with higher odds of previously diagnosed T2DM in men, but not in women. Less emotional support related to important decisions, less practical support related to jobs, and less practical support for sickness were associated with newly diagnosed and previously diagnosed T2DM in men and women, but not in pre-diabetes. Conclusion: This study shows that several aspects of structural and functional characteristics of the social network were associated with newly and previously diagnosed T2DM, partially different for men and women. These results may provide useful targets for T2DM prevention efforts.",
keywords = "Pre-diabetes, Prevention, Social network, Social support, Type 2 diabetes",
author = "Stephanie Brinkhues and Dukers-Muijrers, {Nicole H.T.M.} and Hoebe, {Christian J.P.A.} and {Van Der Kallen}, {Carla J.H.} and Dagnelie, {Pieter C.} and Annemarie Koster and Henry, {Ronald M.A.} and Sep, {Simone J.S.} and Schaper, {Nicolaas C.} and Stehouwer, {Coen D.A.} and Hans Bosma and Savelkoul, {Paul H.M.} and Schram, {Miranda T.}",
year = "2017",
month = "12",
day = "19",
doi = "10.1186/s12889-017-4948-6",
language = "English",
volume = "17",
journal = "BMC Public Health",
issn = "1471-2458",
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Brinkhues, S, Dukers-Muijrers, NHTM, Hoebe, CJPA, Van Der Kallen, CJH, Dagnelie, PC, Koster, A, Henry, RMA, Sep, SJS, Schaper, NC, Stehouwer, CDA, Bosma, H, Savelkoul, PHM & Schram, MT 2017, 'Socially isolated individuals are more prone to have newly diagnosed and prevalent type 2 diabetes mellitus - The Maastricht study - The M' BMC Public Health, vol. 17, no. 1, 955. https://doi.org/10.1186/s12889-017-4948-6

Socially isolated individuals are more prone to have newly diagnosed and prevalent type 2 diabetes mellitus - The Maastricht study - The M. / Brinkhues, Stephanie; Dukers-Muijrers, Nicole H.T.M.; Hoebe, Christian J.P.A.; Van Der Kallen, Carla J.H.; Dagnelie, Pieter C.; Koster, Annemarie; Henry, Ronald M.A.; Sep, Simone J.S.; Schaper, Nicolaas C.; Stehouwer, Coen D.A.; Bosma, Hans; Savelkoul, Paul H.M.; Schram, Miranda T.

In: BMC Public Health, Vol. 17, No. 1, 955, 19.12.2017.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - Socially isolated individuals are more prone to have newly diagnosed and prevalent type 2 diabetes mellitus - The Maastricht study - The M

AU - Brinkhues, Stephanie

AU - Dukers-Muijrers, Nicole H.T.M.

AU - Hoebe, Christian J.P.A.

AU - Van Der Kallen, Carla J.H.

AU - Dagnelie, Pieter C.

AU - Koster, Annemarie

AU - Henry, Ronald M.A.

AU - Sep, Simone J.S.

AU - Schaper, Nicolaas C.

AU - Stehouwer, Coen D.A.

AU - Bosma, Hans

AU - Savelkoul, Paul H.M.

AU - Schram, Miranda T.

PY - 2017/12/19

Y1 - 2017/12/19

N2 - Background: Social isolation is associated with type 2 diabetes (T2DM), but it is unclear which elements play a crucial role in this association. Therefore, we assessed the associations of a broad range of structural and functional social network characteristics with normal glucose metabolism, pre-diabetes, newly diagnosed T2DM and previously diagnosed T2DM. Methods: Participants originated from The Maastricht Study, a population-based cohort study (n = 2861, mean age 60.0 ± 8.2 years, 49% female, 28.8% T2DM (oversampled)). Social network characteristics were assessed through a name generator questionnaire. Diabetes status was determined by an oral glucose tolerance test. We used multinomial regression analyses to investigate the associations between social network characteristics and diabetes status, stratified by sex. Results: More socially isolated individuals (smaller social network size) more frequently had newly diagnosed and previously diagnosed T2DM, while this association was not observed with pre-diabetes. In women, proximity and the type of relationship was associated with newly diagnosed and previously diagnosed T2DM. A lack of social participation was associated with pre-diabetes as well as with previously diagnosed T2DM in women, and with previously diagnosed T2DM in men. Living alone was associated with higher odds of previously diagnosed T2DM in men, but not in women. Less emotional support related to important decisions, less practical support related to jobs, and less practical support for sickness were associated with newly diagnosed and previously diagnosed T2DM in men and women, but not in pre-diabetes. Conclusion: This study shows that several aspects of structural and functional characteristics of the social network were associated with newly and previously diagnosed T2DM, partially different for men and women. These results may provide useful targets for T2DM prevention efforts.

AB - Background: Social isolation is associated with type 2 diabetes (T2DM), but it is unclear which elements play a crucial role in this association. Therefore, we assessed the associations of a broad range of structural and functional social network characteristics with normal glucose metabolism, pre-diabetes, newly diagnosed T2DM and previously diagnosed T2DM. Methods: Participants originated from The Maastricht Study, a population-based cohort study (n = 2861, mean age 60.0 ± 8.2 years, 49% female, 28.8% T2DM (oversampled)). Social network characteristics were assessed through a name generator questionnaire. Diabetes status was determined by an oral glucose tolerance test. We used multinomial regression analyses to investigate the associations between social network characteristics and diabetes status, stratified by sex. Results: More socially isolated individuals (smaller social network size) more frequently had newly diagnosed and previously diagnosed T2DM, while this association was not observed with pre-diabetes. In women, proximity and the type of relationship was associated with newly diagnosed and previously diagnosed T2DM. A lack of social participation was associated with pre-diabetes as well as with previously diagnosed T2DM in women, and with previously diagnosed T2DM in men. Living alone was associated with higher odds of previously diagnosed T2DM in men, but not in women. Less emotional support related to important decisions, less practical support related to jobs, and less practical support for sickness were associated with newly diagnosed and previously diagnosed T2DM in men and women, but not in pre-diabetes. Conclusion: This study shows that several aspects of structural and functional characteristics of the social network were associated with newly and previously diagnosed T2DM, partially different for men and women. These results may provide useful targets for T2DM prevention efforts.

KW - Pre-diabetes

KW - Prevention

KW - Social network

KW - Social support

KW - Type 2 diabetes

UR - http://www.scopus.com/inward/record.url?scp=85038414750&partnerID=8YFLogxK

U2 - 10.1186/s12889-017-4948-6

DO - 10.1186/s12889-017-4948-6

M3 - Article

VL - 17

JO - BMC Public Health

JF - BMC Public Health

SN - 1471-2458

IS - 1

M1 - 955

ER -