Abstract

Objectives: Standing desks and stability balls are increasingly popular to increase muscle activity and thereby prevent potential adverse cardiometabolic effects of prolonged sitting. The present study examined the effects of (1) sitting on a stability ball (‘active sitting’) and (2) hourly 10-min standing interruptions during prolonged sitting on postprandial cardiometabolic biomarkers. Design: Experimental crossover study. Methods: Twenty healthy-weight males (19.2 ± 0.6 years) participated randomly in three 5-h conditions: (1) sitting on an office chair (SIT), (2) sitting on a stability ball (SIT-ACTIVE) and (3) sitting with hourly 10-min standing interruptions (SIT-STAND). In each condition, participants consumed a standardized mixed meal at baseline. Hourly blood samples and pre/post saliva samples were collected and analyzed for levels of insulin, glucose and cortisol. Pre/post hemodynamic monitoring (middle finger; Nexfin-monitoring) was conducted; heart rate was measured continuously (Polar) and muscle activity (leg and lower-back, Portilab) was measured during periods of sitting (on an office chair and on a stability ball) and standing. Results: Muscle activity and heart rate during standing periods were significantly higher than during sitting (both SIT and SIT-ACTIVE). Generalized estimating equations revealed no significant difference in any of the biomarkers between the three experimental conditions. Systolic blood pressure was lower during SIT-STAND, while stroke volume was lower during SIT-ACTIVE than during SIT. Although significant, these differences were small, approximating the day-to-day variability in blood pressure and stroke volume. Conclusions: We conclude that hourly standing interruptions during 5 h prolonged sitting or continuously sitting on a stability ball do not significantly affect postprandial cardiometabolic biomarkers in healthy young men. Trial registration: This trial is registered in the NTR trial register (NTRcode 5723).

LanguageEnglish
JournalJournal of Science and Medicine in Sport
DOIs
Publication statusAccepted/In press - 1 Jan 2019

Cite this

@article{ef6622b94f434e0387d36943e3ef2414,
title = "Standing is not enough: A randomized crossover study on the acute cardiometabolic effects of variations in sitting in healthy young men",
abstract = "Objectives: Standing desks and stability balls are increasingly popular to increase muscle activity and thereby prevent potential adverse cardiometabolic effects of prolonged sitting. The present study examined the effects of (1) sitting on a stability ball (‘active sitting’) and (2) hourly 10-min standing interruptions during prolonged sitting on postprandial cardiometabolic biomarkers. Design: Experimental crossover study. Methods: Twenty healthy-weight males (19.2 ± 0.6 years) participated randomly in three 5-h conditions: (1) sitting on an office chair (SIT), (2) sitting on a stability ball (SIT-ACTIVE) and (3) sitting with hourly 10-min standing interruptions (SIT-STAND). In each condition, participants consumed a standardized mixed meal at baseline. Hourly blood samples and pre/post saliva samples were collected and analyzed for levels of insulin, glucose and cortisol. Pre/post hemodynamic monitoring (middle finger; Nexfin-monitoring) was conducted; heart rate was measured continuously (Polar) and muscle activity (leg and lower-back, Portilab) was measured during periods of sitting (on an office chair and on a stability ball) and standing. Results: Muscle activity and heart rate during standing periods were significantly higher than during sitting (both SIT and SIT-ACTIVE). Generalized estimating equations revealed no significant difference in any of the biomarkers between the three experimental conditions. Systolic blood pressure was lower during SIT-STAND, while stroke volume was lower during SIT-ACTIVE than during SIT. Although significant, these differences were small, approximating the day-to-day variability in blood pressure and stroke volume. Conclusions: We conclude that hourly standing interruptions during 5 h prolonged sitting or continuously sitting on a stability ball do not significantly affect postprandial cardiometabolic biomarkers in healthy young men. Trial registration: This trial is registered in the NTR trial register (NTRcode 5723).",
keywords = "Active sitting, Cortisol, Glucose, Insulin, Postprandial, Sedentary",
author = "Altenburg, {Teatske M.} and Joost Rotteveel and Sern{\'e}, {Erik H.} and Chinapaw, {Mai J.M.}",
year = "2019",
month = "1",
day = "1",
doi = "10.1016/j.jsams.2018.12.016",
language = "English",
journal = "Journal of Science and Medicine in Sport",
issn = "1440-2440",
publisher = "Elsevier BV",

}

TY - JOUR

T1 - Standing is not enough

T2 - Journal of Science and Medicine in Sport

AU - Altenburg, Teatske M.

AU - Rotteveel, Joost

AU - Serné, Erik H.

AU - Chinapaw, Mai J.M.

PY - 2019/1/1

Y1 - 2019/1/1

N2 - Objectives: Standing desks and stability balls are increasingly popular to increase muscle activity and thereby prevent potential adverse cardiometabolic effects of prolonged sitting. The present study examined the effects of (1) sitting on a stability ball (‘active sitting’) and (2) hourly 10-min standing interruptions during prolonged sitting on postprandial cardiometabolic biomarkers. Design: Experimental crossover study. Methods: Twenty healthy-weight males (19.2 ± 0.6 years) participated randomly in three 5-h conditions: (1) sitting on an office chair (SIT), (2) sitting on a stability ball (SIT-ACTIVE) and (3) sitting with hourly 10-min standing interruptions (SIT-STAND). In each condition, participants consumed a standardized mixed meal at baseline. Hourly blood samples and pre/post saliva samples were collected and analyzed for levels of insulin, glucose and cortisol. Pre/post hemodynamic monitoring (middle finger; Nexfin-monitoring) was conducted; heart rate was measured continuously (Polar) and muscle activity (leg and lower-back, Portilab) was measured during periods of sitting (on an office chair and on a stability ball) and standing. Results: Muscle activity and heart rate during standing periods were significantly higher than during sitting (both SIT and SIT-ACTIVE). Generalized estimating equations revealed no significant difference in any of the biomarkers between the three experimental conditions. Systolic blood pressure was lower during SIT-STAND, while stroke volume was lower during SIT-ACTIVE than during SIT. Although significant, these differences were small, approximating the day-to-day variability in blood pressure and stroke volume. Conclusions: We conclude that hourly standing interruptions during 5 h prolonged sitting or continuously sitting on a stability ball do not significantly affect postprandial cardiometabolic biomarkers in healthy young men. Trial registration: This trial is registered in the NTR trial register (NTRcode 5723).

AB - Objectives: Standing desks and stability balls are increasingly popular to increase muscle activity and thereby prevent potential adverse cardiometabolic effects of prolonged sitting. The present study examined the effects of (1) sitting on a stability ball (‘active sitting’) and (2) hourly 10-min standing interruptions during prolonged sitting on postprandial cardiometabolic biomarkers. Design: Experimental crossover study. Methods: Twenty healthy-weight males (19.2 ± 0.6 years) participated randomly in three 5-h conditions: (1) sitting on an office chair (SIT), (2) sitting on a stability ball (SIT-ACTIVE) and (3) sitting with hourly 10-min standing interruptions (SIT-STAND). In each condition, participants consumed a standardized mixed meal at baseline. Hourly blood samples and pre/post saliva samples were collected and analyzed for levels of insulin, glucose and cortisol. Pre/post hemodynamic monitoring (middle finger; Nexfin-monitoring) was conducted; heart rate was measured continuously (Polar) and muscle activity (leg and lower-back, Portilab) was measured during periods of sitting (on an office chair and on a stability ball) and standing. Results: Muscle activity and heart rate during standing periods were significantly higher than during sitting (both SIT and SIT-ACTIVE). Generalized estimating equations revealed no significant difference in any of the biomarkers between the three experimental conditions. Systolic blood pressure was lower during SIT-STAND, while stroke volume was lower during SIT-ACTIVE than during SIT. Although significant, these differences were small, approximating the day-to-day variability in blood pressure and stroke volume. Conclusions: We conclude that hourly standing interruptions during 5 h prolonged sitting or continuously sitting on a stability ball do not significantly affect postprandial cardiometabolic biomarkers in healthy young men. Trial registration: This trial is registered in the NTR trial register (NTRcode 5723).

KW - Active sitting

KW - Cortisol

KW - Glucose

KW - Insulin

KW - Postprandial

KW - Sedentary

UR - http://www.scopus.com/inward/record.url?scp=85059817637&partnerID=8YFLogxK

U2 - 10.1016/j.jsams.2018.12.016

DO - 10.1016/j.jsams.2018.12.016

M3 - Article

JO - Journal of Science and Medicine in Sport

JF - Journal of Science and Medicine in Sport

SN - 1440-2440

ER -