Strategies to optimize respiratory muscle function in ICU patients

Willem-Jan M Schellekens, Hieronymus W H van Hees, Jonne Doorduin, Lisanne H Roesthuis, Gert Jan Scheffer, Johannes G van der Hoeven, Leo M A Heunks

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Respiratory muscle dysfunction may develop rapidly in critically ill ventilated patients and is associated with increased morbidity, length of intensive care unit stay, costs, and mortality. This review briefly discusses the pathophysiology of respiratory muscle dysfunction in intensive care unit patients and then focuses on strategies that prevent the development of muscle weakness or, if weakness has developed, how respiratory muscle function may be improved. We propose a simple strategy for how these can be implemented in clinical care.

Original languageEnglish
Article number103
JournalCritical Care
Volume20
Issue number1
DOIs
Publication statusPublished - 19 Apr 2016

Cite this

Schellekens, W-J. M., van Hees, H. W. H., Doorduin, J., Roesthuis, L. H., Scheffer, G. J., van der Hoeven, J. G., & Heunks, L. M. A. (2016). Strategies to optimize respiratory muscle function in ICU patients. Critical Care, 20(1), [103]. https://doi.org/10.1186/s13054-016-1280-y
Schellekens, Willem-Jan M ; van Hees, Hieronymus W H ; Doorduin, Jonne ; Roesthuis, Lisanne H ; Scheffer, Gert Jan ; van der Hoeven, Johannes G ; Heunks, Leo M A. / Strategies to optimize respiratory muscle function in ICU patients. In: Critical Care. 2016 ; Vol. 20, No. 1.
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Schellekens, W-JM, van Hees, HWH, Doorduin, J, Roesthuis, LH, Scheffer, GJ, van der Hoeven, JG & Heunks, LMA 2016, 'Strategies to optimize respiratory muscle function in ICU patients' Critical Care, vol. 20, no. 1, 103. https://doi.org/10.1186/s13054-016-1280-y

Strategies to optimize respiratory muscle function in ICU patients. / Schellekens, Willem-Jan M; van Hees, Hieronymus W H; Doorduin, Jonne; Roesthuis, Lisanne H; Scheffer, Gert Jan; van der Hoeven, Johannes G; Heunks, Leo M A.

In: Critical Care, Vol. 20, No. 1, 103, 19.04.2016.

Research output: Contribution to journalArticleAcademicpeer-review

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AU - Schellekens, Willem-Jan M

AU - van Hees, Hieronymus W H

AU - Doorduin, Jonne

AU - Roesthuis, Lisanne H

AU - Scheffer, Gert Jan

AU - van der Hoeven, Johannes G

AU - Heunks, Leo M A

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AB - Respiratory muscle dysfunction may develop rapidly in critically ill ventilated patients and is associated with increased morbidity, length of intensive care unit stay, costs, and mortality. This review briefly discusses the pathophysiology of respiratory muscle dysfunction in intensive care unit patients and then focuses on strategies that prevent the development of muscle weakness or, if weakness has developed, how respiratory muscle function may be improved. We propose a simple strategy for how these can be implemented in clinical care.

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KW - Time Factors

KW - Treatment Outcome

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Schellekens W-JM, van Hees HWH, Doorduin J, Roesthuis LH, Scheffer GJ, van der Hoeven JG et al. Strategies to optimize respiratory muscle function in ICU patients. Critical Care. 2016 Apr 19;20(1). 103. https://doi.org/10.1186/s13054-016-1280-y