Subjective quality of life in psychosis: Evidence for an association with real world functioning?

Pien Leendertse, Inez Myin-Germeys, Tineke Lataster, Claudia J. P. Simons, Margreet Oorschot, Mariëlle Lardinois, Maude Schneider, Jim van Os, Ulrich Reininghaus, Berhooz Z. Alizadeh, Agna A. Bartels-Velthuis, Nico J. van Beveren, Richard Bruggeman, Wiepke Cahn, Lieuwe de Haan, Phillipe Delespaul, Carin J. Meijer, Inez Myin-Germeys, Rene S. Kahn, Frederike SchirmbeckClaudia J. P. Simons, Neeltje E. van Haren, Jim van Os, Ruud van Winkel

Research output: Contribution to journalArticleAcademicpeer-review


Subjective quality of life (SQOL) is an established patient-reported outcome in psychosis. However, current self-report measures of SQOL may be affected by recall bias and may not fully capture dynamic changes in SQOL over time. This study aimed to examine the ecological validity of self-reported and momentary assessment measures of SQOL, and their association with emotional experience, social interaction and activity in real life, in both patients with psychotic disorder (n = 56) and controls (n = 71). Self-reported QOL was assessed with the WHO-QOL, momentary QOL and real life experiences were assessed with the Experience Sampling Method (ESM). Results show that both measures were significantly associated in patients and controls, and associations with emotional experience were most relevant, momentary QOL being a stronger predictor than self-reported QOL. The association between momentary QOL and negative affect was stronger in patients than in controls. Overall, momentary QOL was more consistently associated with affect, social interaction and activity, while self-reported QOL displayed a more narrow association with mostly affect. Concluding, concurrent assessment of self-reported QOL and momentary QOL showed that momentary QOL may enhance the ecological validity of SQOL measurement. Experience sampling research may broaden our perspective on SQOL and its associations with real life functioning.
Original languageEnglish
Pages (from-to)116-123
JournalPsychiatry Research
Publication statusPublished - 2018
Externally publishedYes

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