Successful fibrinolytic therapy for massive pulmonary embolism during pregnancy

H. M. Oudemans-van Straaten, C. P. Stoutenbeek, S. Van Der Lans, M. F. Schutte

Research output: Contribution to journalArticleAcademicpeer-review


A case of massive pulmonary embolism with shock during the 27th week of pregnancy was treated successfully with streptokinase infusion into the pulmonary artery, mechanical ventilation and circulatory support. Lysis of the emboli was monitored by the difference between arterial and end-tidal PCO2. Although the fibrinolytic therapy induced bleeding in the mother, it caused no harm to the foetus which was delivered successfully at full-term.

Original languageEnglish
Pages (from-to)77-79
Number of pages3
JournalClinical Intensive Care
Issue number2
Publication statusPublished - 1 Jan 1990

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