Supplemental data for Blood platelets contain tumor-derived RNA biomarkers

R. Jonas A Nilsson, Leonora Balaj, Esther Hulleman, Sjoerd Van Rijn, D. Michiel Pegtel, Maudy Walraven, Anders Widmark, Winald R. Gerritsen, Henk M. Verheul, W. Peter Vandertop, David P. Noske, Johan Skog, Thomas Wurdinger

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

We report on the growth mechanism of spherical silicon nanocrystals in a remote expanding Ar plasma using a time-modulated SiH4 gas injection in the microsecond time range. Under identical time-modulation parameters, we varied the local density of the SiH4 gas by changing its stagnation pressure on the injection line over the range of 0.1–2.0 bar. We observed that nanocrystals were synthesized in a size range from ∼2 to ∼50 nm with monocrystalline morphology. Smaller nanocrystals (∼2–6 nm) with narrower size distributions and with higher number densities were synthesized with an increase of the SiH4 gas-phase density. We related this observation to the rapid depletion of the number density of the molecules, ions, and radicals in the plasma during nanocrystal growth, which can primarily occur via nucleation with no significant subsequent coagulation. In addition, in our remote plasma environment, rapid cooling of the gas in the particle growth zone from ∼1500 to ∼400 K significantly reduces the coalescence...
Original languageEnglish
Pages (from-to)17-20
Number of pages4
JournalJournal of Applied Physics
Volume5
Issue numberXxx
DOIs
Publication statusPublished - 2019

Cite this

Nilsson, R. Jonas A ; Balaj, Leonora ; Hulleman, Esther ; Van Rijn, Sjoerd ; Pegtel, D. Michiel ; Walraven, Maudy ; Widmark, Anders ; Gerritsen, Winald R. ; Verheul, Henk M. ; Vandertop, W. Peter ; Noske, David P. ; Skog, Johan ; Wurdinger, Thomas. / Supplemental data for Blood platelets contain tumor-derived RNA biomarkers. In: Journal of Applied Physics. 2019 ; Vol. 5, No. Xxx. pp. 17-20.
@article{236d5b45130d4ae1a9eeef0aba49402c,
title = "Supplemental data for Blood platelets contain tumor-derived RNA biomarkers",
abstract = "We report on the growth mechanism of spherical silicon nanocrystals in a remote expanding Ar plasma using a time-modulated SiH4 gas injection in the microsecond time range. Under identical time-modulation parameters, we varied the local density of the SiH4 gas by changing its stagnation pressure on the injection line over the range of 0.1–2.0 bar. We observed that nanocrystals were synthesized in a size range from ∼2 to ∼50 nm with monocrystalline morphology. Smaller nanocrystals (∼2–6 nm) with narrower size distributions and with higher number densities were synthesized with an increase of the SiH4 gas-phase density. We related this observation to the rapid depletion of the number density of the molecules, ions, and radicals in the plasma during nanocrystal growth, which can primarily occur via nucleation with no significant subsequent coagulation. In addition, in our remote plasma environment, rapid cooling of the gas in the particle growth zone from ∼1500 to ∼400 K significantly reduces the coalescence...",
author = "Nilsson, {R. Jonas A} and Leonora Balaj and Esther Hulleman and {Van Rijn}, Sjoerd and Pegtel, {D. Michiel} and Maudy Walraven and Anders Widmark and Gerritsen, {Winald R.} and Verheul, {Henk M.} and Vandertop, {W. Peter} and Noske, {David P.} and Johan Skog and Thomas Wurdinger",
year = "2019",
doi = "10.1182/blood-2011-03-344408.The",
language = "English",
volume = "5",
pages = "17--20",
journal = "Journal of Applied Physics",
issn = "0021-8979",
publisher = "American Institute of Physics",
number = "Xxx",

}

Supplemental data for Blood platelets contain tumor-derived RNA biomarkers. / Nilsson, R. Jonas A; Balaj, Leonora; Hulleman, Esther; Van Rijn, Sjoerd; Pegtel, D. Michiel; Walraven, Maudy; Widmark, Anders; Gerritsen, Winald R.; Verheul, Henk M.; Vandertop, W. Peter; Noske, David P.; Skog, Johan; Wurdinger, Thomas.

In: Journal of Applied Physics, Vol. 5, No. Xxx, 2019, p. 17-20.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - Supplemental data for Blood platelets contain tumor-derived RNA biomarkers

AU - Nilsson, R. Jonas A

AU - Balaj, Leonora

AU - Hulleman, Esther

AU - Van Rijn, Sjoerd

AU - Pegtel, D. Michiel

AU - Walraven, Maudy

AU - Widmark, Anders

AU - Gerritsen, Winald R.

AU - Verheul, Henk M.

AU - Vandertop, W. Peter

AU - Noske, David P.

AU - Skog, Johan

AU - Wurdinger, Thomas

PY - 2019

Y1 - 2019

N2 - We report on the growth mechanism of spherical silicon nanocrystals in a remote expanding Ar plasma using a time-modulated SiH4 gas injection in the microsecond time range. Under identical time-modulation parameters, we varied the local density of the SiH4 gas by changing its stagnation pressure on the injection line over the range of 0.1–2.0 bar. We observed that nanocrystals were synthesized in a size range from ∼2 to ∼50 nm with monocrystalline morphology. Smaller nanocrystals (∼2–6 nm) with narrower size distributions and with higher number densities were synthesized with an increase of the SiH4 gas-phase density. We related this observation to the rapid depletion of the number density of the molecules, ions, and radicals in the plasma during nanocrystal growth, which can primarily occur via nucleation with no significant subsequent coagulation. In addition, in our remote plasma environment, rapid cooling of the gas in the particle growth zone from ∼1500 to ∼400 K significantly reduces the coalescence...

AB - We report on the growth mechanism of spherical silicon nanocrystals in a remote expanding Ar plasma using a time-modulated SiH4 gas injection in the microsecond time range. Under identical time-modulation parameters, we varied the local density of the SiH4 gas by changing its stagnation pressure on the injection line over the range of 0.1–2.0 bar. We observed that nanocrystals were synthesized in a size range from ∼2 to ∼50 nm with monocrystalline morphology. Smaller nanocrystals (∼2–6 nm) with narrower size distributions and with higher number densities were synthesized with an increase of the SiH4 gas-phase density. We related this observation to the rapid depletion of the number density of the molecules, ions, and radicals in the plasma during nanocrystal growth, which can primarily occur via nucleation with no significant subsequent coagulation. In addition, in our remote plasma environment, rapid cooling of the gas in the particle growth zone from ∼1500 to ∼400 K significantly reduces the coalescence...

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SN - 0021-8979

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