Survival and Neurodevelopmental Outcomes of Preterms Resuscitated With Different Oxygen Fractions

N. Boronat, M. Aguar, Denise Rook, M. Iriondo, M. Brugada, M. Cernada, A. Nunez, M. Izquierdo, E. Cubells, M. Martinez, A. Parra, H. van Goudoever, M. Vento

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Abstract

BACKGROUND AND OBJECTIVES: Stabilization of preterm infants after birth frequently requires oxygen supplementation. At present the optimal initial oxygen inspiratory fraction (FiO(2)) for preterm stabilization after birth is still under debate. We aimed to compare neurodevelopmental outcomes of extremely preterm infants at 24 months corrected age randomly assigned to be stabilized after birth with an initial FiO(2) of 0.3 versus 0.6 to 0.65 in 3 academic centers from Spain and the Netherlands. METHODS: Randomized, controlled, double-blinded, multicenter, international clinical trial enrolling preterm infants
Original languageEnglish
Pages (from-to)9
Number of pages1
JournalPediatrics
Volume138
DOIs
Publication statusPublished - 2016

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