The association of aberrant folylpolyglutamate synthetase splicing with ex vivo methotrexate resistance and clinical outcome in childhood acute lymphoblastic leukemia

Anna Wojtuszkiewicz; Yehuda G. Assaraf; Mirthe Hoekstra; Rocco Sciarrillo; Gerrit Jansen; Godefridus J. Peters; Rob Pieters; Edwin Sonneveld; Gabriele Escherich; Gertjan J. L. Kaspers; Jacqueline Cloos

doi:10.3324/haematol.2016.142794

The association of aberrant folylpolyglutamate synthetase splicing with ex vivo methotrexate resistance and clinical outcome in childhood acute lymphoblastic leukemia

Anna Wojtuszkiewicz, Yehuda G. Assaraf, Mirthe Hoekstra, Rocco Sciarrillo, Gerrit Jansen, Godefridus J. Peters, Rob Pieters, Edwin Sonneveld, Gabriele Escherich, Gertjan J. L. Kaspers, Jacqueline Cloos

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	291-294
Journal	Haematologica
Volume	101
Issue number	7
DOIs	https://doi.org/10.3324/haematol.2016.142794
Publication status	Published - Jul 2016

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10.3324/haematol.2016.142794

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Wojtuszkiewicz, A., Assaraf, Y. G., Hoekstra, M., Sciarrillo, R., Jansen, G., Peters, G. J., ... Cloos, J. (2016). The association of aberrant folylpolyglutamate synthetase splicing with ex vivo methotrexate resistance and clinical outcome in childhood acute lymphoblastic leukemia. Haematologica, 101(7), 291-294. https://doi.org/10.3324/haematol.2016.142794

Wojtuszkiewicz, Anna ; Assaraf, Yehuda G. ; Hoekstra, Mirthe ; Sciarrillo, Rocco ; Jansen, Gerrit ; Peters, Godefridus J. ; Pieters, Rob ; Sonneveld, Edwin ; Escherich, Gabriele ; Kaspers, Gertjan J. L. ; Cloos, Jacqueline. / The association of aberrant folylpolyglutamate synthetase splicing with ex vivo methotrexate resistance and clinical outcome in childhood acute lymphoblastic leukemia. In: Haematologica. 2016 ; Vol. 101, No. 7. pp. 291-294.

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title = "The association of aberrant folylpolyglutamate synthetase splicing with ex vivo methotrexate resistance and clinical outcome in childhood acute lymphoblastic leukemia",

keywords = "pediatric acute lymphoblastic leukemia, aberrant splicing, dexamethasone, folylpolyglutamate synthetase, methotrexate",

author = "Anna Wojtuszkiewicz and Assaraf, {Yehuda G.} and Mirthe Hoekstra and Rocco Sciarrillo and Gerrit Jansen and Peters, {Godefridus J.} and Rob Pieters and Edwin Sonneveld and Gabriele Escherich and Kaspers, {Gertjan J. L.} and Jacqueline Cloos",

year = "2016",

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doi = "10.3324/haematol.2016.142794",

language = "English",

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Wojtuszkiewicz, A, Assaraf, YG, Hoekstra, M, Sciarrillo, R, Jansen, G , Peters, GJ, Pieters, R, Sonneveld, E, Escherich, G, Kaspers, GJL & Cloos, J 2016, 'The association of aberrant folylpolyglutamate synthetase splicing with ex vivo methotrexate resistance and clinical outcome in childhood acute lymphoblastic leukemia', Haematologica, vol. 101, no. 7, pp. 291-294. https://doi.org/10.3324/haematol.2016.142794

The association of aberrant folylpolyglutamate synthetase splicing with ex vivo methotrexate resistance and clinical outcome in childhood acute lymphoblastic leukemia. / Wojtuszkiewicz, Anna; Assaraf, Yehuda G.; Hoekstra, Mirthe; Sciarrillo, Rocco; Jansen, Gerrit ; Peters, Godefridus J.; Pieters, Rob; Sonneveld, Edwin; Escherich, Gabriele; Kaspers, Gertjan J. L.; Cloos, Jacqueline.

In: Haematologica, Vol. 101, No. 7, 07.2016, p. 291-294.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - The association of aberrant folylpolyglutamate synthetase splicing with ex vivo methotrexate resistance and clinical outcome in childhood acute lymphoblastic leukemia

AU - Wojtuszkiewicz, Anna

AU - Assaraf, Yehuda G.

AU - Hoekstra, Mirthe

AU - Sciarrillo, Rocco

AU - Jansen, Gerrit

AU - Peters, Godefridus J.

AU - Pieters, Rob

AU - Sonneveld, Edwin

AU - Escherich, Gabriele

AU - Kaspers, Gertjan J. L.

AU - Cloos, Jacqueline

PY - 2016/7

Y1 - 2016/7

KW - pediatric acute lymphoblastic leukemia

KW - aberrant splicing

KW - dexamethasone

KW - folylpolyglutamate synthetase

KW - methotrexate

U2 - 10.3324/haematol.2016.142794

DO - 10.3324/haematol.2016.142794

M3 - Article

C2 - 27036162

VL - 101

SP - 291

EP - 294

JO - Haematologica

JF - Haematologica

SN - 0390-6078

IS - 7

ER -