The course of behavioral problems in elderly nursing home patients with dementia when treated with antipsychotics

B.C. Kleijer, R.J. van Marum, A.C. Egberts, P.A.F. Jansen, D.H.M. Frijters, E. Heerdink, M.W. Ribbe

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Abstract

BACKGROUND: Although antipsychotic treatment of behavioral problems in dementia is common, studies investigating the course of these symptoms in nursing homes are scarce. Our primary objective is therefore to describe the course of behavioral problems during antipsychotic treatment in a large sample of elderly nursing home patients with dementia. METHODS: The course of behavioral problems during antipsychotic treatment was studied by comparing the characteristics of patients before, during and after antipsychotic treatment. The study was conducted using the VURAIDB, a database with over 40,000 assessments of over 10,000 nursing home residents in the Netherlands. We used the Challenging Behavior Profile (CBP) to measure an overall behavior score. RESULTS: In total, 556 patients starting with antipsychotics were studied. Of these, 101 (18.2%) improved and 260 (46.8%) deteriorated at three months on the behavior score, compared with their scores before therapy (z = -7.955; P
Original languageUndefined/Unknown
Pages (from-to)931-940
JournalInternational Psychogeriatrics
Volume21
Issue number5
DOIs
Publication statusPublished - 2009

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