Abstract
Background: The Dutch Audit for Carotid Interventions (DACI) registers all patients undergoing interventions for carotid artery stenosis in the Netherlands. This study describes the design of the DACI and results of patients with a symptomatic stenosis undergoing carotid endarterectomy (CEA). It aimed to evaluate variation between hospitals in process of care and (adjusted) outcomes, as well as predictors of major stroke/death after CEA. Methods: All patients with a symptomatic stenosis, who underwent CEA and were registered in the DACI between 2014 and 2016 were included in this cohort. Descriptive analyses of patient characteristics, process of care, and outcomes were performed. Casemix adjusted hospital procedural outcomes as (30 day/in hospital) mortality, stroke/death, and major stroke/death, were compared with the national mean. A multivariable logistic regression model (backward elimination at p > 0.10) was used to identify predictors of major stroke/death. Results: A total of 6459 patients, registered by 52 hospitals, were included. The majority (4,832, 75%) were treated <2 weeks after their first hospital consultation, varying from 40% to 93% between hospitals. Mortality, stroke/death, and major stroke/death were, respectively, 1.1%, 3.6%, and 1.8%. Adjusted major stroke/death rates for hospital comparison varied between 0 and 6.5%. Nine hospitals performed significantly better, none performed significantly worse. Predictors of major stroke/death were sex, age, pulmonary disease, presenting neurological symptoms, and peri-operative shunt. Conclusion: CEA in The Netherlands is associated with an overall low mortality and (major) stroke/death rate. Whereas the indicator time to intervention varied between hospitals, mortality and (major) stroke/death were not significantly distinctive enough to identify worse practices and therefore were unsuitable for hospital comparison in the Dutch setting. Additionally, predictors of major stroke/death at population level could be identified.
Original language | English |
---|---|
Pages (from-to) | 476-485 |
Number of pages | 10 |
Journal | European Journal of Vascular and Endovascular Surgery |
Volume | 56 |
Issue number | 4 |
DOIs | |
Publication status | Published - Oct 2018 |
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The Dutch Audit of Carotid Interventions : Transparency in Quality of Carotid Endarterectomy in Symptomatic Patients in the Netherlands. / the Dutch Society of Vascular Surgery; the Steering Committee of the Dutch Audit for Carotid Interventions; the Dutch Institute for Clinical Auditing.
In: European Journal of Vascular and Endovascular Surgery, Vol. 56, No. 4, 10.2018, p. 476-485.Research output: Contribution to journal › Article › Academic › peer-review
TY - JOUR
T1 - The Dutch Audit of Carotid Interventions
T2 - Transparency in Quality of Carotid Endarterectomy in Symptomatic Patients in the Netherlands
AU - Karthaus, Eleonora G.
AU - Vahl, Anco
AU - Kuhrij, Laurien S.
AU - Elsman, Bernard H.P.
AU - Geelkerken, Robert H.
AU - Wouters, Michel W.J.M.
AU - Hamming, Jaap F.
AU - de Borst, Gert J.
AU - Van den Akker, L. H.
AU - Van den Akker, P. J.
AU - Akkersdijk, G. J.
AU - Akkersdijk, G. P.
AU - Akkersdijk, W. L.
AU - van Andringa de Kempenaer, M. G.
AU - Arts, C. H.
AU - Avontuur, J. A.
AU - Baal, J. G.
AU - Bakker, O. J.
AU - Balm, R.
AU - Barendregt, W. B.
AU - Bender, M. H.
AU - Bendermacher, B. L.
AU - van den Berg, M.
AU - Berger, P.
AU - Beuk, R. J.
AU - Blankensteijn, J. D.
AU - Bleker, R. J.
AU - Bockel, J. H.
AU - Bodegom, M. E.
AU - Bogt, K. E.
AU - Boll, A. P.
AU - Booster, M. H.
AU - Borger van der Burg, B. L.
AU - de Borst, G. J.
AU - Bos- van Rossum, W. T.
AU - Bosma, J.
AU - Botman, J. M.
AU - Bouwman, L. H.
AU - Breek, J. C.
AU - Brehm, V.
AU - Brinckman, M. J.
AU - van den Broek, T. H.
AU - Brom, H. L.
AU - de Bruijn, M. T.
AU - de Bruin, J. L.
AU - Brummel, P.
AU - van Brussel, J. P.
AU - Buijk, S. E.
AU - Buimer, M. G.
AU - Burger, D. H.
AU - Buscher, H. C.
AU - den Butter, G.
AU - Cancrinus, E.
AU - Castenmiller, P. H.
AU - Cazander, G.
AU - Coveliers, H. M.
AU - Cuypers, P. H.
AU - Daemen, J. H.
AU - Dawson, I.
AU - Derom, A. F.
AU - Dijkema, A. R.
AU - Diks, J.
AU - Dinkelman, M. K.
AU - Dirven, M.
AU - Dolmans, D. E.
AU - van Doorn, R. C.
AU - van Dortmont, L. M.
AU - van der Eb, M. M.
AU - Eefting, D.
AU - van Eijck, G. J.
AU - Elshof, Jan Willem
AU - Elsman, Bernard H.P.
AU - van der Elst, A.
AU - van Engeland, M. I.
AU - van Eps, R. G.
AU - Faber, M. J.
AU - de Fijter, W. M.
AU - Fioole, B.
AU - Fritschy, W. M.
AU - Geelkerken, Robert H.
AU - van Gent, W. B.
AU - Glade, G. J.
AU - Govaert, B.
AU - Groenendijk, R. P.
AU - de Groot, H. G.
AU - van den Haak, R. F.
AU - de Haan, E. F.
AU - Hajer, G. F.
AU - Hamming, Jaap F.
AU - van Hattum, E. S.
AU - Hazenberg, C. E.
AU - Hedeman Joosten, P. P.
AU - Helleman, J. N.
AU - van der Hem, L. G.
AU - Hendriks, J. M.
AU - van Herwaarden, J. A.
AU - Heyligers, J. M.
AU - Hinnen, J. W.
AU - Hissink, R. J.
AU - Ho, G. H.
AU - den Hoed, P. T.
AU - Hoedt, M. T.
AU - van Hoek, F.
AU - Hoencamp, R.
AU - Hoffmann, W. H.
AU - Hoksbergen, A. W.
AU - Hollander, E. J.
AU - Huisman, L. C.
AU - Hulsebos, R. G.
AU - Huntjens, K. M.
AU - Idu, M. M.
AU - Jacobs, M. J.
AU - van der Jagt, M. F.
AU - Jansbeken, J. R.
AU - Janssen, R. J.
AU - Jiang, H. H.
AU - de Jong, S. C.
AU - Jongkind, V.
AU - Kapma, M. R.
AU - Keller, B. P.
AU - Khodadade Jahrome, A.
AU - Kievit, J. K.
AU - Klemm, P. L.
AU - Klinkert, P.
AU - Knippenberg, B.
AU - Koedam, N. A.
AU - Koelemaij, M. J.
AU - Kolkert, J. L.
AU - Koning, G. G.
AU - Koning, O. H.
AU - Krasznai, A. G.
AU - Krol, R. M.
AU - Kropman, R. H.
AU - Kruse, R. R.
AU - van der Laan, L.
AU - van der Laan, M. J.
AU - van Laanen, J. H.
AU - Lardenoye, J. H.
AU - Lawson, J. A.
AU - Legemate, D. A.
AU - Leijdekkers, V. J.
AU - Lemson, M. S.
AU - Lensvelt, M. M.
AU - Lijkwan, M. A.
AU - Lind, R. C.
AU - van der Linden, F. T.
AU - Liqui Lung, P. F.
AU - Loos, M. J.
AU - Loubert, M. C.
AU - Mahmoud, D. E.
AU - Manshanden, C. G.
AU - Mattens, E. C.
AU - Meerwaldt, R.
AU - Mees, B. M.
AU - Metz, R.
AU - Minnee, R. C.
AU - de Mol van Otterloo, J. C.
AU - Moll, F. L.
AU - Montauban van Swijndregt, Y. C.
AU - Morak, M. J.
AU - van de Mortel, R. H.
AU - Mulder, W.
AU - Nagesser, S. K.
AU - Naves, C. C.
AU - Nederhoed, J. H.
AU - Nevenzel-Putters, A. M.
AU - de Nie, A. J.
AU - Nieuwenhuis, D. H.
AU - Nieuwenhuizen, J.
AU - van Nieuwenhuizen, R. C.
AU - Nio, D.
AU - Oomen, A. P.
AU - Oranen, B. I.
AU - Oskam, J.
AU - Palamba, H. W.
AU - Peppelenbosch, A. G.
AU - van Petersen, A. S.
AU - Peterson, T. F.
AU - Petri, B. J.
AU - Pierie, M. E.
AU - Ploeg, A. J.
AU - Pol, R. A.
AU - Ponfoort, E. D.
AU - Poyck, P. P.
AU - Prent, A.
AU - ten Raa, S.
AU - Raymakers, J. T.
AU - Reichart, M.
AU - Reichmann, B. L.
AU - Reijnen, M. M.
AU - Rijbroek, A.
AU - van Rijn, M. J.
AU - de Roo, R. A.
AU - Rouwet, E. V.
AU - Rupert, C. G.
AU - Saleem, B. R.
AU - van Sambeek, M. R.
AU - Samyn, M. G.
AU - van ‘t Sant, H. P.
AU - van Schaik, J.
AU - van Schaik, P. M.
AU - Scharn, D. M.
AU - Scheltinga, M. R.
AU - Schepers, A.
AU - Schlejen, P. M.
AU - Schlosser, F. J.
AU - Schol, F. P.
AU - Schouten, O.
AU - Schreinemacher, M. H.
AU - Schreve, M. A.
AU - Schurink, G. W.
AU - Sikkink, C. J.
AU - Siroen, M. P.
AU - te Slaa, A.
AU - Smeets, H. J.
AU - Smeets, L.
AU - de Smet, A. A.
AU - de Smit, P.
AU - Smit, P. C.
AU - Smits, T. M.
AU - Snoeijs, M. G.
AU - Sondakh, A. O.
AU - van der Steenhoven, T. J.
AU - van Sterkenburg, S. M.
AU - Stigter, D. A.
AU - Stigter, H.
AU - Strating, R. P.
AU - Stultiëns, D.
AU - Sybrandy, J. E.
AU - Teijink, J. A.
AU - Telgenkamp, B. J.
AU - Testroote, M. J.
AU - The, R. M.
AU - Thijsse, W. J.
AU - Tielliu, I. F.
AU - van Tongeren, R. B.
AU - Toorop, R. J.
AU - Tordoir, J. H.
AU - Tournoij, E.
AU - Truijers, M.
AU - Türkcan, K.
AU - Tutein Nolthenius, R. P.
AU - Ünlü,
AU - Vafi, A. A.
AU - Vahl, A. C.
AU - Veen, E. J.
AU - Veger, H. T.
AU - Veldman, M. G.
AU - Verhagen, H. J.
AU - Verhoeven, B. A.
AU - Vermeulen, C. F.
AU - Vermeulen, E. G.
AU - Vierhout, B. P.
AU - Visser, M. J.
AU - van der Vliet, J. A.
AU - Vlijmen - van Keulen, C. J.
AU - Voesten, H. G.
AU - Voorhoeve, R.
AU - Vos, A. W.
AU - de Vos, B.
AU - Vos, G. A.
AU - Vriens, B. H.
AU - Vriens, P. W.
AU - de Vries, A. C.
AU - de Vries, J. P.
AU - de Vries, M.
AU - van der Waal, C.
AU - Waasdorp, E. J.
AU - Wallis de Vries, B. M.
AU - van Walraven, L. A.
AU - van Wanroij, J. L.
AU - Warlé, M. C.
AU - van Weel, V.
AU - van Well, A. M.
AU - Welten, G. M.
AU - Welten, R. J.
AU - Wever, J. J.
AU - Wiersema, A. M.
AU - Wikkeling, O. R.
AU - Willaert, W. I.
AU - Wille, J.
AU - Willems, M. C.
AU - Willigendael, E. M.
AU - Wisselink, W.
AU - Witte, M. E.
AU - Wittens, C. H.
AU - Wolf-de Jonge, I. C.
AU - Yazar, O.
AU - Zeebregts, C. J.
AU - van Zeeland, M. L.
AU - de Borst, Gert J.
AU - Elsman, Bernard H.P.
AU - Elshof, Jan Willem
AU - Geelkerken, Robert H.
AU - Hamming, Jaap F.
AU - Vahl, Anco
AU - Willems, Martine C.
AU - the Dutch Society of Vascular Surgery
AU - the Steering Committee of the Dutch Audit for Carotid Interventions
AU - the Dutch Institute for Clinical Auditing
PY - 2018/10
Y1 - 2018/10
N2 - Background: The Dutch Audit for Carotid Interventions (DACI) registers all patients undergoing interventions for carotid artery stenosis in the Netherlands. This study describes the design of the DACI and results of patients with a symptomatic stenosis undergoing carotid endarterectomy (CEA). It aimed to evaluate variation between hospitals in process of care and (adjusted) outcomes, as well as predictors of major stroke/death after CEA. Methods: All patients with a symptomatic stenosis, who underwent CEA and were registered in the DACI between 2014 and 2016 were included in this cohort. Descriptive analyses of patient characteristics, process of care, and outcomes were performed. Casemix adjusted hospital procedural outcomes as (30 day/in hospital) mortality, stroke/death, and major stroke/death, were compared with the national mean. A multivariable logistic regression model (backward elimination at p > 0.10) was used to identify predictors of major stroke/death. Results: A total of 6459 patients, registered by 52 hospitals, were included. The majority (4,832, 75%) were treated <2 weeks after their first hospital consultation, varying from 40% to 93% between hospitals. Mortality, stroke/death, and major stroke/death were, respectively, 1.1%, 3.6%, and 1.8%. Adjusted major stroke/death rates for hospital comparison varied between 0 and 6.5%. Nine hospitals performed significantly better, none performed significantly worse. Predictors of major stroke/death were sex, age, pulmonary disease, presenting neurological symptoms, and peri-operative shunt. Conclusion: CEA in The Netherlands is associated with an overall low mortality and (major) stroke/death rate. Whereas the indicator time to intervention varied between hospitals, mortality and (major) stroke/death were not significantly distinctive enough to identify worse practices and therefore were unsuitable for hospital comparison in the Dutch setting. Additionally, predictors of major stroke/death at population level could be identified.
AB - Background: The Dutch Audit for Carotid Interventions (DACI) registers all patients undergoing interventions for carotid artery stenosis in the Netherlands. This study describes the design of the DACI and results of patients with a symptomatic stenosis undergoing carotid endarterectomy (CEA). It aimed to evaluate variation between hospitals in process of care and (adjusted) outcomes, as well as predictors of major stroke/death after CEA. Methods: All patients with a symptomatic stenosis, who underwent CEA and were registered in the DACI between 2014 and 2016 were included in this cohort. Descriptive analyses of patient characteristics, process of care, and outcomes were performed. Casemix adjusted hospital procedural outcomes as (30 day/in hospital) mortality, stroke/death, and major stroke/death, were compared with the national mean. A multivariable logistic regression model (backward elimination at p > 0.10) was used to identify predictors of major stroke/death. Results: A total of 6459 patients, registered by 52 hospitals, were included. The majority (4,832, 75%) were treated <2 weeks after their first hospital consultation, varying from 40% to 93% between hospitals. Mortality, stroke/death, and major stroke/death were, respectively, 1.1%, 3.6%, and 1.8%. Adjusted major stroke/death rates for hospital comparison varied between 0 and 6.5%. Nine hospitals performed significantly better, none performed significantly worse. Predictors of major stroke/death were sex, age, pulmonary disease, presenting neurological symptoms, and peri-operative shunt. Conclusion: CEA in The Netherlands is associated with an overall low mortality and (major) stroke/death rate. Whereas the indicator time to intervention varied between hospitals, mortality and (major) stroke/death were not significantly distinctive enough to identify worse practices and therefore were unsuitable for hospital comparison in the Dutch setting. Additionally, predictors of major stroke/death at population level could be identified.
KW - Carotid endarterectomy
KW - CEA
KW - National clinical audit
KW - Quality of care
KW - Symptomatic carotid artery stenosis
UR - http://www.scopus.com/inward/record.url?scp=85050799392&partnerID=8YFLogxK
U2 - 10.1016/j.ejvs.2018.05.030
DO - 10.1016/j.ejvs.2018.05.030
M3 - Article
C2 - 30077438
AN - SCOPUS:85050799392
SN - 1078-5884
VL - 56
SP - 476
EP - 485
JO - European Journal of Vascular and Endovascular Surgery
JF - European Journal of Vascular and Endovascular Surgery
IS - 4
ER -