TY - JOUR
T1 - The effects of once- versus twice-weekly sessions on psychotherapy outcomes in depressed patients
AU - Bruijniks, Sanne J.E.
AU - Lemmens, Lotte H.J.M.
AU - Hollon, Steven D.
AU - Peeters, Frenk P.M.L.
AU - Cuijpers, Pim
AU - Arntz, Arnoud
AU - DIngemanse, Pieter
AU - Willems, Linda
AU - Van Oppen, Patricia
AU - Twisk, Jos W.R.
AU - Van Den Boogaard, Michael
AU - Spijker, Jan
AU - Bosmans, Judith
AU - Huibers, Marcus J.H.
PY - 2020/4/1
Y1 - 2020/4/1
N2 - Background It is unclear what session frequency is most effective in cognitive-behavioural therapy (CBT) and interpersonal psychotherapy (IPT) for depression.Aims Compare the effects of once weekly and twice weekly sessions of CBT and IPT for depression.Method We conducted a multicentre randomised trial from November 2014 through December 2017. We recruited 200 adults with depression across nine specialised mental health centres in the Netherlands. This study used a 2 × 2 factorial design, randomising patients to once or twice weekly sessions of CBT or IPT over 16-24 weeks, up to a maximum of 20 sessions. Main outcome measures were depression severity, measured with the Beck Depression Inventory-II at baseline, before session 1, and 2 weeks, 1, 2, 3, 4, 5 and 6 months after start of the intervention. Intention-to-treat analyses were conducted.Results Compared with patients who received weekly sessions, patients who received twice weekly sessions showed a statistically significant decrease in depressive symptoms (estimated mean difference between weekly and twice weekly sessions at month 6: 3.85 points, difference in effect size d = 0.55), lower attrition rates (n = 16 compared with n = 32) and an increased rate of response (hazard ratio 1.48, 95% CI 1.00-2.18).Conclusions In clinical practice settings, delivery of twice weekly sessions of CBT and IPT for depression is a way to improve depression treatment outcomes.
AB - Background It is unclear what session frequency is most effective in cognitive-behavioural therapy (CBT) and interpersonal psychotherapy (IPT) for depression.Aims Compare the effects of once weekly and twice weekly sessions of CBT and IPT for depression.Method We conducted a multicentre randomised trial from November 2014 through December 2017. We recruited 200 adults with depression across nine specialised mental health centres in the Netherlands. This study used a 2 × 2 factorial design, randomising patients to once or twice weekly sessions of CBT or IPT over 16-24 weeks, up to a maximum of 20 sessions. Main outcome measures were depression severity, measured with the Beck Depression Inventory-II at baseline, before session 1, and 2 weeks, 1, 2, 3, 4, 5 and 6 months after start of the intervention. Intention-to-treat analyses were conducted.Results Compared with patients who received weekly sessions, patients who received twice weekly sessions showed a statistically significant decrease in depressive symptoms (estimated mean difference between weekly and twice weekly sessions at month 6: 3.85 points, difference in effect size d = 0.55), lower attrition rates (n = 16 compared with n = 32) and an increased rate of response (hazard ratio 1.48, 95% CI 1.00-2.18).Conclusions In clinical practice settings, delivery of twice weekly sessions of CBT and IPT for depression is a way to improve depression treatment outcomes.
KW - cognitive-behavioural therapies
KW - Depressive disorders
KW - individual psychotherapy
KW - out-patient treatment
KW - randomised controlled trial
UR - http://www.scopus.com/inward/record.url?scp=85082625878&partnerID=8YFLogxK
U2 - 10.1192/bjp.2019.265
DO - 10.1192/bjp.2019.265
M3 - Article
C2 - 32029012
AN - SCOPUS:85082625878
VL - 216
SP - 222
EP - 230
JO - British Journal of Psychiatry
JF - British Journal of Psychiatry
SN - 0007-1250
IS - 4
ER -