The efficacy of Xialine®in patients with xerostomia resulting from radiotherapy for head and neck cancer: A pilot-study

Anke Petra Jellema*, Hans Langendijk, Lester Bergenhenegouwen, Willy Van Der Reijden, Rene Leemans, Ludy Smeele, Berend J. Slotman

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review


Changes in subjective sensations due to xerostomia before and after administration of Xialine®, a xanthan gum-based saliva substitute, were evaluated in 30 patients with radiation-induced xerostomia using the QLQ-H&N35. Xerostomia in general decreased with both Xialine® and placebo to almost the same degree. A trend was seen for Xialine® to improve problems with speech and senses.

Original languageEnglish
Pages (from-to)157-160
Number of pages4
JournalRadiotherapy and Oncology
Issue number2
Publication statusPublished - 1 May 2001

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