TY - JOUR
T1 - The EHA research Roadmap
T2 - Immune-based therapies for hematological malignancies
AU - Einsele, Hermann
AU - Briones, Javier
AU - Ciceri, Fabio
AU - Cadenas, Irene García
AU - Falkenburg, Fred
AU - Bolaños, Natacha
AU - Heemskerk, H. M.Mirjam
AU - Houot, Roch
AU - Hudecek, Michael
AU - Locatelli, Franco
AU - Morgan, Kate
AU - Morris, Emma C.
AU - O’Dwyer, Michael
AU - Sierra, Jordi Gil
AU - van den Brink, Marcel
AU - van de Loosdrecht, Arjan A.
N1 - Funding Information:
HE is involved in consultation for Janssen, BMS/Celgene, Amgen, Novartis, Takeda, and received royalties of payments from Janssen, BMS/Celgene, Amgen, Novartis, Takeda, GSK, and Sanofi. JB received honoraria from Roche, Takeda, Celgene, Novartis, and Gilead, Consulting for Takeda, Jansen, Celgene, and Gilead/Kyte, research grants from Celgene, and Roche, and travel and accommodation expenses from Roche, Takeda, Celgene, Janssen, and Gilead. HMH received research grant from Miltenyi Biotech. RH received honoraria from Bristol-Myers Squibb, MSD, Gilead, Kite, Roche, Novartis, Janssen, and Celgene. MH is an inventor on patent applications and granted patents related to CAR-T cell therapy and a speaker honoraria from Celgene/BMS, Novartis, and Kite/Gilead. FL is involved in consulting for Bellicum Pharmaceutical, AMGEN, Neovii, Novartis, and Sanofi, and received Speaker fees from Miltenyi, Bellicum Pharmaceuticals, AMGEN, Medac, Neovii, Gilead, Takeda, BluebirdBio, Sobi, and Jazz Pharmaceutical. ECM is involved in consulting for Quell Therapeutics Ltd, GSK, and Orchard Therapeutics and a Founder shareholder of Quell Therapeutics Ltd. MOD is involved in consulting for ONK Therapeutics, Janssen, and Abbvie, research grants from BMS, and Janssen, and received fees from Equity ONK Therapeutics. MvdB received horonaria or consulting for Seres Therapeutics, WindMIL Therapeutics, Merck & Co, Inc., Magenta Therapeutics, Frazier Healthcare Partners, Nektar Therapeutics, Notch Therapeutics, Forty Seven Inc., Priothera, Ceramedix, Lygenesis, Pluto Therapeutics, Novartis (Spouse), Kite, Pharmaceuticals (Spouse), and Beigene (Spouse), royalties from Wolters Kluwer, IP Licensing with Seres Therapeutics, and Juno Therapeutics, research grants from Seres Therapeutics and stock options from Series Therapeutics, Notch Therapeutics, and Pluto Therapeutics. All the other authors have no conflicts of interest to disclose.
Publisher Copyright:
Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the European Hematology Association.
PY - 2021
Y1 - 2021
N2 - In 2016, the European Hematology Association (EHA) published the EHA Roadmap for European Hematology Research1 aiming to highlight achievements in the diagnostics and treatment of blood disorders, and to better inform European policy makers and other stakeholders about the urgent clinical and scientific needs and priorities in the field of hematology. Each section was coordinated by 1–2 section editors who were leading international experts in the field. In the 5 years that have followed, advances in the field of hematology have been plentiful. As such, EHA is pleased to present an updated Research Roadmap, now including 11 sections, each of which will be published separately. The updated EHA Research Roadmap identifies the most urgent priorities in hematology research and clinical science, therefore supporting a more informed, focused, and ideally a more funded future for European Hematology Research. the 11 EHA Research Roadmap sections include normal hematopoiesis; malignant lymphoid diseases; malignant myeloid diseases; anemias and related diseases; platelet disorders; blood coagulation and hemostatic disorders; transfusion medicine; infections in hematology; hematopoietic stem cell transplantation; CAR-T and Other cell-based immune therapies; and gene therapy.
AB - In 2016, the European Hematology Association (EHA) published the EHA Roadmap for European Hematology Research1 aiming to highlight achievements in the diagnostics and treatment of blood disorders, and to better inform European policy makers and other stakeholders about the urgent clinical and scientific needs and priorities in the field of hematology. Each section was coordinated by 1–2 section editors who were leading international experts in the field. In the 5 years that have followed, advances in the field of hematology have been plentiful. As such, EHA is pleased to present an updated Research Roadmap, now including 11 sections, each of which will be published separately. The updated EHA Research Roadmap identifies the most urgent priorities in hematology research and clinical science, therefore supporting a more informed, focused, and ideally a more funded future for European Hematology Research. the 11 EHA Research Roadmap sections include normal hematopoiesis; malignant lymphoid diseases; malignant myeloid diseases; anemias and related diseases; platelet disorders; blood coagulation and hemostatic disorders; transfusion medicine; infections in hematology; hematopoietic stem cell transplantation; CAR-T and Other cell-based immune therapies; and gene therapy.
UR - http://www.scopus.com/inward/record.url?scp=85118171102&partnerID=8YFLogxK
U2 - 10.1097/HS9.0000000000000642
DO - 10.1097/HS9.0000000000000642
M3 - Review article
C2 - 34522844
JO - HemaSphere
JF - HemaSphere
SN - 2572-9241
M1 - e642
ER -