The evolving role of radiotherapy in the management of small cell lung cancer

Mark V. Mishra, Alexander V. Louie, Vinai Gondi, Ben Slotman

Research output: Contribution to journalReview articleAcademicpeer-review

Abstract

Small cell lung cancer (SCLC) represents a small but significant subset of newly diagnosed lung cancers. In spite of being both chemo- and radiation-sensitive, SCLC has a high-propensity for recurrence after treatment. Although systemic therapy plays a central role in the management of patients with SCLC, many of the advances in overall survival for patients with SCLC have directly related to the use of radiation therapy. The objective of this review is to discuss the key radiation therapy clinical trials that have defined the current standard-of-care treatment for SCLC, and to review ongoing advances in radiation therapy that may further advance outcomes for patients with SCLC.
Original languageEnglish
Pages (from-to)S2545-S2554
JournalJournal of Thoracic Disease
Volume10
DOIs
Publication statusPublished - 2018

Cite this

Mishra, Mark V. ; Louie, Alexander V. ; Gondi, Vinai ; Slotman, Ben. / The evolving role of radiotherapy in the management of small cell lung cancer. In: Journal of Thoracic Disease. 2018 ; Vol. 10. pp. S2545-S2554.
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abstract = "Small cell lung cancer (SCLC) represents a small but significant subset of newly diagnosed lung cancers. In spite of being both chemo- and radiation-sensitive, SCLC has a high-propensity for recurrence after treatment. Although systemic therapy plays a central role in the management of patients with SCLC, many of the advances in overall survival for patients with SCLC have directly related to the use of radiation therapy. The objective of this review is to discuss the key radiation therapy clinical trials that have defined the current standard-of-care treatment for SCLC, and to review ongoing advances in radiation therapy that may further advance outcomes for patients with SCLC.",
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The evolving role of radiotherapy in the management of small cell lung cancer. / Mishra, Mark V.; Louie, Alexander V.; Gondi, Vinai; Slotman, Ben.

In: Journal of Thoracic Disease, Vol. 10, 2018, p. S2545-S2554.

Research output: Contribution to journalReview articleAcademicpeer-review

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AU - Slotman, Ben

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AB - Small cell lung cancer (SCLC) represents a small but significant subset of newly diagnosed lung cancers. In spite of being both chemo- and radiation-sensitive, SCLC has a high-propensity for recurrence after treatment. Although systemic therapy plays a central role in the management of patients with SCLC, many of the advances in overall survival for patients with SCLC have directly related to the use of radiation therapy. The objective of this review is to discuss the key radiation therapy clinical trials that have defined the current standard-of-care treatment for SCLC, and to review ongoing advances in radiation therapy that may further advance outcomes for patients with SCLC.

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