De Greulich&Pyle-atlas voor het bepalen van de skeletleeftijd nog steeds bruikbaar in een hedendaagse Nederlandse blanke populatie

Translated title of the contribution: The Greulich&Pyle atlas for determining the skeletal age can still be used in a contemporary Dutch white population

R. R. Van Rijn*, M. H. Lequin, S. G.F. Robben, W. C.J. Hop, C. Van Kuijk

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review


Objective. To validate the use of the Greulich&Pyle atlas for determining skeletal age in a healthy contemporary Dutch white population. Design. Diagnostic evaluation study. Methods. In 278 Dutch white boys (mean age: 12.6 years; range: 5.0-19.5), and 294 Dutch white girls (mean age: 12.2 years; range: 5.2-19.9) radiographs of the left hand were scored by two investigators according to the Greulich&Pyle atlas. Participants and their parents or guardians gave informed consent. Results. The intra-observer coefficient of variation of duplicate assessment of skeletal age for the investigators was 2.4% and 1.5% respectively. There were no significant systematic differences between both observers with respect to variability and the agreement between the two was good. There was a strong significant correlation between skeletal and calendar age: rgirls = 0.974 and rboys = 0-979 (both p < 0.001). On average calendar age slightly preceded skeletal age by 1.7 months in girls and 3.3 months in boys (both p < 0.001). Conclusion. The Greulich&Pyle atlas still appears to be applicable in a contemporary Dutch white population.

Original languageDutch
Pages (from-to)701-704
Number of pages4
JournalNederlands Tijdschrift voor Geneeskunde
Issue number15
Publication statusPublished - 12 Apr 2003

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