The Influence of Radiotherapy on the Mechanical Properties of Silicone Breast Implants

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Abstract

Background: Silicone breast implants have been used for decades for cosmetic breast augmentation or reconstruction after mastectomy. In selected cases, postmastectomy adjuvant radiotherapy is given with the breast implants in situ. Previous clinical studies have shown that radiotherapy may lead to complications such as capsular contracture and infection and that removal of the implant may be required. Yet, the effect of radiotherapy on silicone breast implants themselves is unknown. The aim of this study was to investigate if irradiation of breast implants influences their mechanical properties. Methods: This was an ex vivo study on 32 ready-to-use silicone breast implants (Mentor and Silimed). Half of the implants of each brand were irradiated with 1 × 60 Gy, the other half were not irradiated. Tensile, mechanical hysteresis, and rheology tests were performed. Differences in mechanical properties between the irradiated and nonirradiated implants were determined. Results: No significant differences were found in tensile strength, mechanical hysteresis, and rheological properties between irradiated and nonirradiated implants. Conclusions: Breast implants' mechanical properties for these 2 brands were not significantly affected after single-dose irradiation in an ex vivo setting.
Original languageEnglish
Article numbere1772
JournalPlastic and reconstructive surgery.Global open
Volume6
Issue number7
DOIs
Publication statusPublished - 2018

Cite this

@article{a761723f8e654574a04e05b27137b1a2,
title = "The Influence of Radiotherapy on the Mechanical Properties of Silicone Breast Implants",
abstract = "Background: Silicone breast implants have been used for decades for cosmetic breast augmentation or reconstruction after mastectomy. In selected cases, postmastectomy adjuvant radiotherapy is given with the breast implants in situ. Previous clinical studies have shown that radiotherapy may lead to complications such as capsular contracture and infection and that removal of the implant may be required. Yet, the effect of radiotherapy on silicone breast implants themselves is unknown. The aim of this study was to investigate if irradiation of breast implants influences their mechanical properties. Methods: This was an ex vivo study on 32 ready-to-use silicone breast implants (Mentor and Silimed). Half of the implants of each brand were irradiated with 1 × 60 Gy, the other half were not irradiated. Tensile, mechanical hysteresis, and rheology tests were performed. Differences in mechanical properties between the irradiated and nonirradiated implants were determined. Results: No significant differences were found in tensile strength, mechanical hysteresis, and rheological properties between irradiated and nonirradiated implants. Conclusions: Breast implants' mechanical properties for these 2 brands were not significantly affected after single-dose irradiation in an ex vivo setting.",
author = "Yara Bachour and Oei, {Lisanne J.} and {van der Veen}, {Albert J.} and Vos, {Bart E.} and Andre Louis and Stan Heukelom and Ritt, {Marco J. P. F.} and Niessen, {Frank B.} and Koken, {Phil W.} and Winters, {Hay A. H.}",
year = "2018",
doi = "10.1097/GOX.0000000000001772",
language = "English",
volume = "6",
journal = "Plastic and reconstructive surgery.Global open",
issn = "2169-7574",
publisher = "Lippincott Williams and Wilkins Ltd.",
number = "7",

}

TY - JOUR

T1 - The Influence of Radiotherapy on the Mechanical Properties of Silicone Breast Implants

AU - Bachour, Yara

AU - Oei, Lisanne J.

AU - van der Veen, Albert J.

AU - Vos, Bart E.

AU - Louis, Andre

AU - Heukelom, Stan

AU - Ritt, Marco J. P. F.

AU - Niessen, Frank B.

AU - Koken, Phil W.

AU - Winters, Hay A. H.

PY - 2018

Y1 - 2018

N2 - Background: Silicone breast implants have been used for decades for cosmetic breast augmentation or reconstruction after mastectomy. In selected cases, postmastectomy adjuvant radiotherapy is given with the breast implants in situ. Previous clinical studies have shown that radiotherapy may lead to complications such as capsular contracture and infection and that removal of the implant may be required. Yet, the effect of radiotherapy on silicone breast implants themselves is unknown. The aim of this study was to investigate if irradiation of breast implants influences their mechanical properties. Methods: This was an ex vivo study on 32 ready-to-use silicone breast implants (Mentor and Silimed). Half of the implants of each brand were irradiated with 1 × 60 Gy, the other half were not irradiated. Tensile, mechanical hysteresis, and rheology tests were performed. Differences in mechanical properties between the irradiated and nonirradiated implants were determined. Results: No significant differences were found in tensile strength, mechanical hysteresis, and rheological properties between irradiated and nonirradiated implants. Conclusions: Breast implants' mechanical properties for these 2 brands were not significantly affected after single-dose irradiation in an ex vivo setting.

AB - Background: Silicone breast implants have been used for decades for cosmetic breast augmentation or reconstruction after mastectomy. In selected cases, postmastectomy adjuvant radiotherapy is given with the breast implants in situ. Previous clinical studies have shown that radiotherapy may lead to complications such as capsular contracture and infection and that removal of the implant may be required. Yet, the effect of radiotherapy on silicone breast implants themselves is unknown. The aim of this study was to investigate if irradiation of breast implants influences their mechanical properties. Methods: This was an ex vivo study on 32 ready-to-use silicone breast implants (Mentor and Silimed). Half of the implants of each brand were irradiated with 1 × 60 Gy, the other half were not irradiated. Tensile, mechanical hysteresis, and rheology tests were performed. Differences in mechanical properties between the irradiated and nonirradiated implants were determined. Results: No significant differences were found in tensile strength, mechanical hysteresis, and rheological properties between irradiated and nonirradiated implants. Conclusions: Breast implants' mechanical properties for these 2 brands were not significantly affected after single-dose irradiation in an ex vivo setting.

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UR - https://www.ncbi.nlm.nih.gov/pubmed/30175006

U2 - 10.1097/GOX.0000000000001772

DO - 10.1097/GOX.0000000000001772

M3 - Article

VL - 6

JO - Plastic and reconstructive surgery.Global open

JF - Plastic and reconstructive surgery.Global open

SN - 2169-7574

IS - 7

M1 - e1772

ER -