TY - JOUR
T1 - The Mechanisms and Effects of Physical Activity on Breast Cancer
AU - de Boer, Myrte C.
AU - Wörner, Elisabeth A.
AU - Verlaan, Diede
AU - van Leeuwen, Paul A.M.
PY - 2017/7/1
Y1 - 2017/7/1
N2 - Breast cancer is the most common cancer in women. An extensive part of this health problem can be prevented by an active lifestyle. Physical activity can reduce the risk of breast cancer, reduce the rate of recurrence, and increase the survival rate of patients with breast cancer. The aim of this review was to summarize our current knowledge regarding the effects of physical activity on breast cancer risk, recurrence, and survival. Furthermore, we investigated 5 possible underlying mechanisms through which physical activity has an influence on breast cancer (ie, a reduction of sex hormones, metabolic hormones, adipokines and oxidative stress, and an improvement of the immune function). In this review, we give a complete overview of this subject.
AB - Breast cancer is the most common cancer in women. An extensive part of this health problem can be prevented by an active lifestyle. Physical activity can reduce the risk of breast cancer, reduce the rate of recurrence, and increase the survival rate of patients with breast cancer. The aim of this review was to summarize our current knowledge regarding the effects of physical activity on breast cancer risk, recurrence, and survival. Furthermore, we investigated 5 possible underlying mechanisms through which physical activity has an influence on breast cancer (ie, a reduction of sex hormones, metabolic hormones, adipokines and oxidative stress, and an improvement of the immune function). In this review, we give a complete overview of this subject.
KW - Breast cancer
KW - Cancer therapy
KW - Physical activity
KW - Physiology
KW - Prevention
UR - http://www.scopus.com/inward/record.url?scp=85013149602&partnerID=8YFLogxK
U2 - 10.1016/j.clbc.2017.01.006
DO - 10.1016/j.clbc.2017.01.006
M3 - Review article
C2 - 28233686
AN - SCOPUS:85013149602
VL - 17
SP - 272
EP - 278
JO - Clinical Breast Cancer
JF - Clinical Breast Cancer
SN - 1526-8209
IS - 4
ER -