The Mechanisms and Effects of Physical Activity on Breast Cancer

Myrte C. de Boer; Elisabeth A. Wörner; Diede Verlaan; Paul A.M. van Leeuwen

doi:10.1016/j.clbc.2017.01.006

The Mechanisms and Effects of Physical Activity on Breast Cancer

Myrte C. de Boer, Elisabeth A. Wörner, Diede Verlaan, Paul A.M. van Leeuwen^*

^*Corresponding author for this work

Research output: Contribution to journal › Review article › Academic › peer-review

Abstract

Breast cancer is the most common cancer in women. An extensive part of this health problem can be prevented by an active lifestyle. Physical activity can reduce the risk of breast cancer, reduce the rate of recurrence, and increase the survival rate of patients with breast cancer. The aim of this review was to summarize our current knowledge regarding the effects of physical activity on breast cancer risk, recurrence, and survival. Furthermore, we investigated 5 possible underlying mechanisms through which physical activity has an influence on breast cancer (ie, a reduction of sex hormones, metabolic hormones, adipokines and oxidative stress, and an improvement of the immune function). In this review, we give a complete overview of this subject.

Original language	English
Pages (from-to)	272-278
Number of pages	7
Journal	Clinical Breast Cancer
Volume	17
Issue number	4
DOIs	https://doi.org/10.1016/j.clbc.2017.01.006
Publication status	Published - 1 Jul 2017

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10.1016/j.clbc.2017.01.006

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Cite this

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title = "The Mechanisms and Effects of Physical Activity on Breast Cancer",

abstract = "Breast cancer is the most common cancer in women. An extensive part of this health problem can be prevented by an active lifestyle. Physical activity can reduce the risk of breast cancer, reduce the rate of recurrence, and increase the survival rate of patients with breast cancer. The aim of this review was to summarize our current knowledge regarding the effects of physical activity on breast cancer risk, recurrence, and survival. Furthermore, we investigated 5 possible underlying mechanisms through which physical activity has an influence on breast cancer (ie, a reduction of sex hormones, metabolic hormones, adipokines and oxidative stress, and an improvement of the immune function). In this review, we give a complete overview of this subject.",

keywords = "Breast cancer, Cancer therapy, Physical activity, Physiology, Prevention",

author = "{de Boer}, {Myrte C.} and W{\"o}rner, {Elisabeth A.} and Diede Verlaan and {van Leeuwen}, {Paul A.M.}",

year = "2017",

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journal = "Clinical Breast Cancer",

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AU - Wörner, Elisabeth A.

AU - Verlaan, Diede

AU - van Leeuwen, Paul A.M.

PY - 2017/7/1

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N2 - Breast cancer is the most common cancer in women. An extensive part of this health problem can be prevented by an active lifestyle. Physical activity can reduce the risk of breast cancer, reduce the rate of recurrence, and increase the survival rate of patients with breast cancer. The aim of this review was to summarize our current knowledge regarding the effects of physical activity on breast cancer risk, recurrence, and survival. Furthermore, we investigated 5 possible underlying mechanisms through which physical activity has an influence on breast cancer (ie, a reduction of sex hormones, metabolic hormones, adipokines and oxidative stress, and an improvement of the immune function). In this review, we give a complete overview of this subject.

AB - Breast cancer is the most common cancer in women. An extensive part of this health problem can be prevented by an active lifestyle. Physical activity can reduce the risk of breast cancer, reduce the rate of recurrence, and increase the survival rate of patients with breast cancer. The aim of this review was to summarize our current knowledge regarding the effects of physical activity on breast cancer risk, recurrence, and survival. Furthermore, we investigated 5 possible underlying mechanisms through which physical activity has an influence on breast cancer (ie, a reduction of sex hormones, metabolic hormones, adipokines and oxidative stress, and an improvement of the immune function). In this review, we give a complete overview of this subject.

KW - Breast cancer

KW - Cancer therapy

KW - Physical activity

KW - Physiology

KW - Prevention

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